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Envigo offers a large collection of pre-developed genetically engineered ADME/Tox rat models including advanced disease research rat models including drug metabolism and transport and xenobiotic senor models to name a few. Envigo is a leader in molecular and phenotypic services featuring extensive scientific expertise in customized study and assay design, numerous in life and end point measurements, and study flexibility with comprehensive scientific project management.

We are consistently and reliably available to partner with you on a scientific and personal level to design, execute, and deliver exactly what you need to achieve and exceed your research and development goals.

 

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Genetically engineered models (GEMs)

Rat Model Specific Disease/Biological Function Therapeutic Area
Bcrp KO
BSEP KO
CAR KO
Mdr1a KO
Mdr1a/1b KO
Mdr1a-Bcrp KO
Mrp1 KO
Mrp2 KO
Oat1 KO
Oat3 KO
Oct1 KO
Oct2 KO
Drug metabolism, Transporter ADMET
Ppara KO Diabetes, Drug metabolism, Obesity, Xenobiotic ADMET, Immunology
PXR KO
PXR/CAR KO
PXR/CAR/AHR KO
Drug metabolism, Xenobiotic ADMET
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