BALB/c nude mice


Characteristics / Husbandry

  • Coat: Albino
  • The nu allele on chromosome 11 is an autosomal recessive mutation
  • Dysfunctional rudimentary thymus
  • Phenotypically hairless (sparse, intermittent hair growth possible)
  • T-cell deficient
  • B-cells function normal
  • No generation of cytotoxic effector cells
  • No graft versus host response
  • Foxn1nu/Foxn1+ heterogygotes do not show partial expression of the nu phenotype
Tumor Cell Growth
Autoimmune disease
Antibody production
Sentinel model - Heterozygous BALB/cOlaHsd-Foxn1nu/Foxn1+
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Institute of Animal Genetics, Edinburgh to Laboratory Animals Centre, Carshalton, to GD Searle, High Wycombe, to Olac (now Envigo) in 1978.

Order Code: 165(nu)/886(nu/+)

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