Strain:

129S2/SvHsd

Produced in:

U.K.

Research use:

Production of targeted mutations due to the availability of several lines of embryonic stem cells, Ovary transplant and ova transfer studies

Strain:

HsdSage:LE-5HT3a^{tm1(T2A-Cre)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes

Strain:

A/JOlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

General studies, Behavior, Teratogenesis, Carcinogenesis

Strain:

ACI/SegHsd

Produced in:

U.S.

Research use:

Carcinogenesis, Estrogen-induced pituitary growth, Transplant immunology

Strain:

HsdSage:SD-Ahr^tm1Sage

Produced in:

U.S.

Research use:

Xenobiotic sensor, Cytochrome p450 pathways, Drug metabolism, Cholestasis, Hepatotoxicity

Strain:

HsdSage:SD-SNCA^{tm1(SNCA-A53T)Sage}

Produced in:

U.S.

Research use:

Parkinson's disease, Dopaminergic cell toxicity

Strain:

HsdSage:SD-SCNA^tm1Sage

Produced in:

U.S.

Research use:

Parkinson's disease, Dopaminergic cell toxicity

Strain:

HsdSage:SD-ApoE^tm1Sage

Produced in:

U.S.

Research use:

Alzheimer's disease, Neurodegenerative diseases

Strain:

Hsd:Athymic Nude-Foxn1^nu

Produced in:

U.S., U.K., Israel, France

Research use:

Sentinel model - Heterozygous Hsd:Athymic Nude-Foxn1nu/Foxn1+

Strain:

Hsd:RH-Foxn1^rnu

Produced in:

U.S., France

Strain:

NOD.CB17-Prkdc^scid IL2rg^tm1/BcgenHsd

Produced in:

France

Research use:

Infectious disease, Humanization applications

Strain:

B6C3F1/Hsd, B6C3F1/OlaHsd

Produced in:

U.S., The Netherlands

Research use:

Toxicology, Carcinogenicity, Embryo donors

Strain:

B6CBAF1/OlaHsd

Produced in:

The Netherlands

Strain:

B6D2F1/Hsd, B6D2F1/JRccHsd

Produced in:

U.S., The Netherlands, Israel

Research use:

Behavior, Tumorigenicity, Bioassay of nutrients, drugs,  and hormones

Strain:

BALB/cAnNHsd, BALB/cOlaHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

General purpose

Strain:

BALB/cOlaHsd-Foxn1^nu

Produced in:

U.K., Israel, France

Research use:

Autoimmune disease, Antibody production, Sentinel model - Heterozygous BALB/cOlaHsd-Foxn1nu/Foxn1+

Strain:

HsdSage:SD-Abcg2^tm1Sage

Produced in:

U.S.

Research use:

ADMET, DMPK efflux assay, Formulation blood brain barrier efflux, Drug-drug interactions, Tissue distribution, Efficacy assay

Strain:

HsdSage:SD-Bdnf^tm1Sage

Produced in:

U.S.

Research use:

Alzheimer's disease, Depression, Huntington's disease, Memory loss, Nerve growth and development, Pain, Post-traumatic stress disorder, Schizophrenia

Strain:

Hre:Beagle

Produced in:

U.S.

Strain:

BN/RijHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

General Studies, Allergic Respiratory Disease, Nephrology, Leukemia

Strain:

HsdSage:SD-Abcb11^tm1Sage

Produced in:

U.S.

Research use:

Drug-drug interactions, Cholestasis, Drug-induced cholestasis (DIC), Transporter assays

Strain:

C3H/HeNHsd

Produced in:

U.S., The Netherlands, Israel

Research use:

Immunology, General studies, Ocular disease

Strain:

C57BL/6JRccHsd Aged

Produced in:

The Netherlands

Research use:

Metabolism, Cardiovascular, Memory, Osteoarthritis, Neoplasia, Immune response, Longevity, Vision and hearing, Motor skills, Renal degeneration, Age-associated pathology, Neurobiology, Reproductive senescence

Strain:

C57BL/6BrdCrHsd-Tyr^c

Produced in:

U.S., France

Research use:

Source of albino C57BL/6 embryos for chimera generation, Ovarian transfer

Strain:

C57BL/6JOlaHsd, C57BL/6JRccHsd, C57BL/6NHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Background for induced and genetically-modified models, Diet-induced obesity, Superovulation, Behavior and learning disabilities, Drug addiction

Strain:

C57BL/KaLwRijHsd

Produced in:

The Netherlands

Strain:

HsdSage:LE-CAMKIIA^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes

Strain:

HsdSage:SD-NR1I3^tm1Sage

Produced in:

U.S.

Research use:

Xenobiotic sensor, Cytochrome p450 pathways, Cholestasis, Hepatotoxicity, sDrug metabolism

Strain:

CB6F1/Hsd, CB6F1/OlaHsd

Produced in:

U.S., The Netherlands, Israel

Research use:

Immunology, Behavior, Infection, Reproductive Biology

Strain:

CBA/JCrHsd

Produced in:

U.S.

Research use:

Immunology, General purpose, Only approved mouse strain for use in the Local Lymph Node Assay, a refined alternative research method for evaluating the allergic contact dermatitis potential of chemicals and compounds

Strain:

CBA/CaOlaHsd

Produced in:

U.K., The Netherlands

Strain:

HsdHli:CD1-Foxn1^nu

Produced in:

Israel

Research use:

Immunology, Autoimmune disease, Antibody production

Strain:

CD2F1/Hsd

Produced in:

U.S.

Research use:

Carcinogenesis, Pharmacology

Strain:

HsdSage:SD-Cftr^tm1Sage

Produced in:

U.S.

Research use:

Chloride transport, Cystic Fibrosis, Thiocyanide transport

Strain:

HsdSage:SD-Cntnap2^tm1Sage

Produced in:

U.S.

Research use:

Autism Spectrum Disorders, Cell adhesion, Language disorders, Synaptic Plasticity

Strain:

Hsd:Cotton Rat

Produced in:

U.S.

Research use:

Adenoviral vector-based gene therap, Herpes Simplex, Parainfluenza Type 3, Polio, Measles, Monkeypox, Human metapneumovirus, Mycobacterium tuberculosis

Strain:

CrlHli:CD-1

Produced in:

Israel

Strain:

CSJLF1/HliHsd

Produced in:

Israel

Strain:

M. fascicularis

Produced in:

U.S.

Strain:

DA/OlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Oncology, Transplantation, Cardiovascular Experimental allergic encephalomyelitis, Induced rheumatoid arthritis

Strain:

SR/JrHsd, SS/JrHsd

Produced in:

U.S.

Research use:

Salt-sensitive hypertension, Heart failure, Stroke, Nephropathy

Strain:

DBA/1OlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Immunology, Adjuvant-induced arthritis, Inflammation

Strain:

DBA/2JRccHsd, DBA/2NHsd, DBA/2OlaHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Progressive hearing loss, Audiogenic seizures

Strain:

BKS.Cg-+Lepr^db/+Lepr^db/OlaHsd

Produced in:

U.S., The Netherlands

Research use:

Peripheral neuropathy, Immunodeficiency

Strain:

HsdSage:SD-Slc6a3^{tm1(Dat-cre)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes, DREDD

Strain:

HsdDhl:DH

Produced in:

The Netherlands

Research use:

Immunology, Auditory Studies

Strain:

Haz: (DB) SPF

Produced in:

U.S.

Strain:

F344/NHsd Aged

Produced in:

U.S.

Research use:

Metabolism, Cardiovascular, Memory, Osteoarthritis, Neoplasia, Immune response, Longevity, Vision and hearing, Motor skills, Renal degeneration, Age-associated pathology, Neurobiology, Reproductive senescence

Strain:

F344/NHsd

Produced in:

U.S.

Strain:

HsdSage: SD-Fmr1-/null^tm1Sage, HsdSage:SD-Fmr1+/-^tm1Sage, HsdSage:SD-Fmr1^tm1Sage

Produced in:

U.S.

Research use:

Autism, Fragile X syndrome

Strain:

FVB/NHan^®Hsd, FVB/NHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Transgenic model development

Strain:

HsdHan^®:AURA

Produced in:

U.S.

Research use:

Syrian Hamster Embryo (SHE) Cell Transformation Assay, Hypercholesterolemia, Hibernation

Strain:

HsdSage:SD-ApoE2^{tm1(hApoE2)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Dopaminergic cell toxicity

Strain:

HsdSage:SD-ApoE3^{tm1(hApoE3)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Dopaminergic cell toxicity

Strain:

HsdSage:SD-ApoE4^{tm1(hApoE4)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Neurodegenerative diseases

Strain:

HsdHot:Holtzman^® SD^®

Produced in:

U.S.

Research use:

Oncology, Teratology, General studies, Toxicology, Neurology, Reproduction

Strain:

Hsd:ICR (CD-1^®)

Produced in:

U.S., U.K., The Netherlands, Israel

Strain:

HsdSage:SD-Ldlr^tm1Sage

Produced in:

U.S.

Research use:

Atherosclerosis, Hypertension, Insulin resistant, Atherogenesis, Lipoprotein - Cholesterol transportation, Metabolism (Triglyceride - Cholesterol), ObesityType 2 diabetes

Strain:

LEW/Han^®Hsd, LEW/SsNHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Adjuvant-induced arthritis, Experimental allergic encephalomyelitis

Strain:

HsdOla:LH

Produced in:

U.K., The Netherlands

Research use:

Behavior

Strain:

HsdBlu:LE

Produced in:

U.S.

Research use:

Nutrition, Diet-induced obesity

Strain:

HsdSage:LE-Lrrk1^tm1Sage

Produced in:

U.S.

Research use:

Parkinson's disease, Neuronal apoptosis

Strain:

HsdSage:LE-Lrrk1/Lrrk2^tm1Sage

Produced in:

U.S.

Research use:

Parkinson's disease, Neuronal apoptosis

Strain:

HsdSage:LE-Lrrk^tm1Sage

Produced in:

U.S.

Research use:

Parkinson's disease, Neuronal apoptosis

Strain:

HsdSage:SD-Mdr1a^tm1Sage

Produced in:

U.S.

Research use:

DMPK assay, PK-PD efflux assay, Neurotoxicology, Formulation drug-drug interactions, Drug resistance, Blood brain barrier efflux, Efficacy

Strain:

HsdSage:SD-Mdr1a^tm1SageMdr1b^tm1Sage

Produced in:

U.S.

Research use:

DMPK assay, PK-PD efflux assay, Neurotoxicology, Formulation drug-drug interactions, Drug resistance, Blood brain barrier efflux, Efficacy

Strain:

HsdSage:SD-Mdr1a^tm1SageAbcg2^tm1Sage

Produced in:

U.S.

Research use:

DMPK assay, PK-PD efflux assay, Neurotoxicology, Formulation drug-drug interactions, Drug resistance, Blood brain barrier efflux, Efficacy

Strain:

HsdSage:SD-Mecp2^tm1Sage

Produced in:

U.S.

Research use:

Autism, Cognition, Rett syndrome

Strain:

HsdSage:SD-Grm5^tm1Sage

Produced in:

U.S.

Research use:

Autism, Fragile X syndrome, Anxiety, Cognition, Pain, Schizophrenia

Strain:

HsdSage:SD-Abcc1a^tm1Sage

Produced in:

U.S.

Research use:

Drug resistance, Drug transport, Studying excretion pathways in cancer

Strain:

HsdSage:SD-Abcc2^tm1Sage

Produced in:

U.S.

Research use:

Tissue distribution, DMPKPK/PDFormulation, Dubin-Johnson syndrome, Efficacy Drug-drug interactions, Efflux assays

Strain:

Hsd:ND4

Produced in:

U.S.

Research use:

Toxicology, Infectious disease, Retinal ischemia research, Pain and neuroscience

Strain:

HsdSage:SD-Nrxn1^tm1Sage

Produced in:

U.S.

Research use:

Autism, Schizophrenia, Synaptic Plasticity

Strain:

HsdSage:SD-Nlgn3^tm1Sage

Produced in:

U.S.

Research use:

Autism, Asperger's syndrome, Synaptic Plasticity

Strain:

Hra: (NZW) SPF, Hsdlf:NZW, HsdOkd:NZW

Produced in:

U.S., U.K., Israel

Research use:

Dermatology, Ophthalmology, Biomedical Research, Atherosclerosis, Osteology, Studies, Renal Studies

Strain:

NIH/OlaHsd

Produced in:

U.K.

Strain:

Hsd:NIHS

Produced in:

U.S., U.K.

Research use:

General purpose studies

Strain:

HsdCpb:NMRI-Foxn1^nu

Produced in:

France

Research use:

Transplantation, Immunology, Autoimmune disease, Antibody production

Strain:

HsdWin:NMRI

Produced in:

The Netherlands

Strain:

NOD.CB17-Prkdc^scid/NCrHsd

Produced in:

U.S., Israel, France

Strain:

Hsd:NSA(CF-1^®)

Produced in:

U.S.

Research use:

Toxicology, Infectious disease

Strain:

NZB/OlaHsd

Produced in:

U.K.

Strain:

NZBNZWF1/OlaHsd

Produced in:

U.K.

Strain:

NZW/OlaHsd

Produced in:

U.K.

Strain:

B6.V-Lep^ob/OlaHsd

Produced in:

U.K.

Research use:

Gerontology

Strain:

HsdSage:SD-Slc22a1^tm1Sage

Produced in:

U.S.

Research use:

Drug-drug interactions, Drug metabolism, Drug transport, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a2^tm1Sage

Produced in:

U.S.

Research use:

Drug-drug interactions, Drug metabolism, Drug transport, Hepatotoxicity

Strain:

HsdSage:SD-Oprm1^tm1Sage

Produced in:

U.S.

Research use:

Addiction, Analgesia, Nociception, Pain

Strain:

HsdSage:SD-Ngfr^tm1Sage

Produced in:

U.S.

Research use:

Neuronal apoptosis, Analgesia, Nociception, Pain

Strain:

HsdSage:LE-Park2^tm1Sage

Produced in:

U.S.

Research use:

Parkinson's disease, Dopaminergic cell toxicity

Strain:

HsdSage:LE-Park7^tm1Sage

Produced in:

U.S.

Research use:

Parkinson's disease, Dopaminergic cell toxicity

Strain:

HsdSage:LE-Pvalb^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes

Strain:

HsdSage:LE-Pink1^tm1Sage

Produced in:

U.S.

Research use:

Parkinson's disease, Stress-induced neurological dysfunction

Strain:

HsdSage:SD-Ppara^tm1Sage

Produced in:

U.S.

Research use:

Obesity, Diabetes, Inflammation, Autoimmune disorders, Cell proliferation, Lipid metabolism, Wound healing

Strain:

HsdSage:SD-Prkdc^tm1Sage

Produced in:

U.S.

Research use:

Tumor cell growth, Xenograft, Cancer metastasis

Strain:

HsdSage:SD-Nr1i2^tm1Sage

Produced in:

U.S.

Research use:

Xenobiotic sensor, Cytochrome p450 pathways, Drug metabolism, Cholestasis, Hepatotoxicity

Strain:

HsdSage:SD-Nr1i2^tm1SageNr1i3^tm1Sage

Produced in:

U.S.

Research use:

Xenobiotic sensor, Cytochrome p450 pathways, Drug metabolism, Cholestasis, Hepatotoxicity

Strain:

HsdSage:SD-Rag2^tm1sage

Produced in:

U.S.

Research use:

Xenograft, Cancer metastasis, Inflammation - Autoimmune disorders, Thrombosis - Cardiac fibrosis, Vascular defects, Hematopoieses

Strain:

B6;129-Rag2^tm1FwaII2rg^tm1Rsky/DwlHsd

Produced in:

U.S., U.K., Israel, France

Research use:

Infectious disease, Cancer cell transplantation

Strain:

M. mulatta

Produced in:

U.S.

Strain:

HsdHu:SABRA-M

Produced in:

Israel

Strain:

HsdHu:SABRA-R

Produced in:

Israel

Strain:

SAMP8/TaHsd, SAMR1/TaHsd (control)

Produced in:

The Netherlands

Research use:

Geriatric pathogenesis, Senile amyloidosis (apolipoprotein A-II), Hearing impairment, Emotional disorders Aging process, Age-dependent disorders, Senile osteoporosis, Hyperinflation of the lungs, Deficits in learning and memory, Brain atrophy, Accelerated senescence studies

Strain:

C.B-17/IcrHan^®Hsd-Prkdc^scid, C.B-17/IcrHsd-Prkdc^scid

Produced in:

U.S., U.K., Israel, France

Strain:

C.B-17/IcrHsd-Prkdc^scidLyst^bg-J

Produced in:

U.S., Israel, France

Research use:

Teratology

Strain:

NOD.Cg-Prkdc^scidHr^hr/NCrHsd

Produced in:

France

Research use:

Xenograft transplantation, Imaging applications, Humanization applications

Strain:

SJL/JCrHsd

Produced in:

U.S., The Netherlands, Israel

Research use:

Immunology, Behavior

Strain:

SHR/NHsd

Produced in:

U.S., U.K.

Research use:

Hypertension, Insulin resistant

Strain:

Hsd:Sprague Dawley^® SD^® Aged

Produced in:

U.S.

Research use:

Metabolism, Cardiovascular, Memory, Osteoarthritis, Neoplasia, Immune response, Longevity, Vision and hearing, Motor skills, Renal degeneration, Age-associated pathology, Neurobiology, Reproductive senescence

Strain:

Hsd:Sprague Dawley^® SD^®

Produced in:

U.S., U.K., The Netherlands, Israel

Strain:

LEH-SST-cre^tm1sage

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes

Strain:

HsdSage:LE-Rosa26^{tm1(tdTomato)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression of td, Tomato fluorescence when Cre-recombinase is introduced

Strain:

HsdOla:TO

Produced in:

U.K.

Research use:

General purpose

Strain:

HsdSage:LE-Tph2^{tm1(T2A-Cre)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes

Strain:

HsdSage:SD-Trpv1^tm1Sage

Produced in:

U.S.

Research use:

Analgesia, Cannabinoids, Nociception, Pain, Thermoregulation

Strain:

HsdSage:SD-TH^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes, DREADD

Strain:

HsdSage:LE-VGAT^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes

Strain:

HsdSage:LE-VIP^{tm1(T2A-Cre)Sage}

Produced in:

U.S.

Research use:

Optogenetics, Expression/knockout of floxed genes

Strain:

WF/NHsd

Produced in:

U.S.

Research use:

Transplantation, Immunology, Leukemia

Strain:

RccHan^®:WIST

Produced in:

U.S., U.K., The Netherlands

Strain:

WKY/NHsd

Produced in:

U.S., U.K.

Research use:

Immunology, Inbred, normotensive control for SHR rat

Strain:

Hsd:WI

Produced in:

U.S.

Research use:

Oncology, Teratology, Nutrition, Aging

Strain:

HsdCpb:WU

Produced in:

The Netherlands

Research use:

Oncology, Teratology, Nutrition, Aging, General purpose model

Strain:

HsdHlr:ZUCKER-Lepr^fa

Produced in:

U.S.