Strain:

129S2/SvHsd

Produced in:

U.K.

Research use:

Ovary transplant and ova transfer studies, Production of targeted mutations due to the availability of several lines of embryonic stem cells

Strain:

HsdSage:LE-5HT3a^{tm1(T2A-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in 5HT3a+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

A/JOlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Behavior, Carcinogenesis, General studies, Teratogenesis

Strain:

ACI/SegHsd

Produced in:

U.S.

Research use:

Carcinogenesis, Estrogen-induced pituitary growth, Transplant immunology

Strain:

HsdSage:SD-Ahr^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-SNCA^{tm1(SNCA-A53T)Sage}

Produced in:

U.S.

Research use:

Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Strain:

HsdSage:SD-SCNA^tm1Sage

Produced in:

U.S.

Research use:

Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Strain:

HsdSage:SD-ApoE^tm1Sage

Produced in:

U.S.

Research use:

Atherosclerosis, Neuroscience, Alzheimer's disease, Cardiovascular, Neurodegenerative diseases, Neuroscience

Strain:

HsdSage:SD-App^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Alzheimer's disease, Dementia, Memory loss, Neurodegeneration, Neuroscience, Synaptic formation and repair

Strain:

Hsd:Athymic Nude-Foxn1^nu, Hsd:Athymic Nude-Foxn1^nu/Foxn1⁺

Produced in:

U.S., U.K., Israel, France

Research use:

Autoimmune disease, Gene therapy, General studies, Immunology, Oncology, Transplantation, Tumor growth, Sentinel model - Heterozygous Hsd:Athymic Nude-Foxn1^nu/Foxn1⁺

Strain:

Hsd:RH-Foxn1^rnu, Hsd:RH-Foxn1^rnu/Foxn1⁺

Produced in:

U.S., France

Research use:

General studies, Immunology, Oncology, Transplantation, Sentinel model – Heterozygous Hsd:RH-Foxn1^rnu/Foxn1⁺

Strain:

NOD.CB17-Prkdc^scid IL2rg^tm1/BcgenHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Chemoresistance, Immunotherapy, Oncology, Stem cells, Tumor growth, Humanization applications, Infectious disease

Strain:

B6C3F1/Hsd, B6C3F1/OlaHsd

Produced in:

U.S., The Netherlands

Research use:

Carcinogenicity, Embryo donors, Toxicology

Strain:

B6CBAF1/OlaHsd

Produced in:

The Netherlands

Strain:

B6D2F1/Hsd, B6D2F1/JRccHsd

Produced in:

U.S., The Netherlands, Israel

Research use:

Behavior, Bioassay of nutrients, drugs, and hormones, Tumorigenicity

Strain:

BALB/cAnNHsd, BALB/cOlaHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Aging, Cardiovascular, COVID-19, General studies, Infectious disease, Monoclonal antibodies, Oncology, Pharmacology, Teratology, Toxicology, Transplantation, General purpose

Strain:

BALB/cOlaHsd-Foxn1^nu, BALB/cOlaHsd-Foxn1^nu/Foxn1⁺

Produced in:

U.K., Israel, France

Research use:

Imaging, Immunology, Oncology, Transplantation, Tumor growth, Antibody production, Autoimmune disease, Sentinel model - Heterozygous BALB/cOlaHsd-Foxn1^nu/Foxn1⁺

Strain:

HsdSage:SD-Abcg2^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Aging, Immunotherapy, Oncology, Stem cells, Tissue distribution, Tumor growth, DMPK efflux assay, Drug-drug interactions, Drug metabolism, Drug transporter, Efficacy assay, Formulation blood brain barrier efflux, Neuroscience, Tissue distribution

Strain:

HsdSage:SD-Bdnf^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Neuroscience, Alzheimer's disease, Depression, Huntington's disease, Memory loss, Nerve growth and development, Neuroscience, Pain, Post-traumatic stress disorder, Schizophrenia

Strain:

HsdHre:Beagle

Produced in:

U.S.

Research use:

Cellular therapies, General studies, Ocular studies, Pharmacology, Toxicology

Strain:

BN/RijHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, General studies, Oncology, Transplantation, Allergic Respiratory Disease, Leukemia, Nephrology

Strain:

HsdSage:SD-Abcb11^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Drug-drug interactions, Drug-induced cholestasis (DIC), Drug metabolism, Drug transporter

Strain:

C3H/HeNHsd

Produced in:

U.S., The Netherlands, Israel

Research use:

General studies, Immunology, Ocular disease

Strain:

C57BL/6JRccHsd Aged

Produced in:

The Netherlands

Research use:

Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Osteoarthritis, Neoplasia, Neurobiology, Renal degeneration, Reproductive senescence, Vision and hearing

Strain:

C57BL/6BrdCrHsd-Tyr^c

Produced in:

U.S., U.K., France

Research use:

Ovarian transfer, Source of albino C57BL/6 embryos for chimera generation

Strain:

C57BL/6JOlaHsd, C57BL/6JRccHsd, C57BL/6NHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Aging, Alcoholism, Alpha Synuclein, Behavior, Behavioral and learning disabilities, Cardiovascular, COVID-19, Diabetes type 2, Diet induced obesity, General studies, Genetically modified, Immunology, Neuroscience, Oncology, Toxicology, Vaccines, Background for induced and genetically-modified models, Behavior and learning disabilities, Diet-induced obesity, Drug addiction, Superovulation

Strain:

C57BL/KaLwRijHsd

Produced in:

The Netherlands

Strain:

HsdSage:SD-Cacna1c^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neurodegeneration, Social behavior, Alzheimer's disease, Autism (ASD), Dementia, Memory loss, Neuroscience, Synaptic formation and repair

Strain:

HsdSage:LE-CAMKIIA^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Cre Tool for conditional expression or deletion in CamKIIa+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-NR1I3^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cytochrome p450 pathways, Cholestasis, Hepatotoxicity, Drug metabolism, Xenobiotic

Strain:

CB6F1/Hsd, CB6F1/OlaHsd

Produced in:

U.S., The Netherlands, Israel

Research use:

Behavior, Immunology, Infection, Reproductive Biology

Strain:

CBA/JCrHsd

Produced in:

U.S.

Research use:

General purpose, Immunology, Only approved mouse strain for use in the Local Lymph Node Assay, a refined alternative research method for evaluating the allergic contact dermatitis potential of chemicals and compounds

Strain:

CBA/CaOlaHsd

Produced in:

U.K., The Netherlands

Strain:

CrlHli:CD-1

Produced in:

Israel

Research use:

General studies

Strain:

HsdHli:CD1-Foxn1^nu, HsdHli:CD1-Foxn1^nu/Foxn1⁺

Produced in:

Israel

Research use:

General studies, Oncology, Surgical, Transplantation, Tumor growth, Antibody production, Autoimmune disease, Immunology

Strain:

CD2F1/Hsd

Produced in:

U.S.

Research use:

Carcinogenesis, Pharmacology

Strain:

HsdSage:SD-Cftr^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Lung Disease, Chloride transport, Cystic Fibrosis, Lung Disease, Thiocyanide transport

Strain:

HsdSage:SD-CHD8^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neuroscience

Strain:

HsdSage:SD-Chrna7^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Epilepsy, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Strain:

HsdSage:SD-Cntnap2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Cell adhesion, Language disorders, Synaptic Plasticity

Strain:

Hsd:Cotton Rat

Produced in:

U.S.

Research use:

Infectious disease, Adenoviral vector-based gene therap, Herpes Simplex, Human metapneumovirus, Measles, Monkeypox, Mycobacterium tuberculosis, Parainfluenza Type 3, Polio

Strain:

HsdSage:SD-Cox1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:SD-Cox2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

CSJLF1/HliHsd

Produced in:

Israel

Strain:

M. fascicularis

Produced in:

U.S.

Research use:

Cellular therapies, COVID-19, Diabetes, General studies, Immunology, Infectious disease, Neuroscience, Obesity, Pharmacology, Toxicology

Strain:

DA/OlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Cardiovascular Experimental allergic encephalomyelitis, Induced rheumatoid arthritis, Oncology, Transplantation

Strain:

SR/JrHsd, SS/JrHsd

Produced in:

U.S.

Research use:

Heart failure, Nephropathy, Salt-sensitive hypertension, Stroke

Strain:

DBA/1OlaHsd

Produced in:

U.S., U.K., The Netherlands

Research use:

Adjuvant-induced arthritis, Immunology, Inflammation

Strain:

DBA/2JRccHsd, DBA/2NHsd, DBA/2OlaHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Audiogenic seizures, Progressive hearing loss

Strain:

BKS.Cg-+Lepr^db/+Lepr^db/OlaHsd, BKS.Cg-Dock7^m+/+Lepr^db/OlaHsd, BKS.Cg-Dock7^m +/Dock7^m+/OlaHsd, BKS.Cg-(Lean)/OlaHsd

Produced in:

U.S., The Netherlands

Research use:

General studies, Immunology, Obesity, Immunodeficiency, Peripheral neuropathy

Strain:

HsdSage:SD-Disc1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Bipolar disorder, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Strain:

HsdSage:SD-Slc6a3^{tm1(Dat-cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expession or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage: LE-Slc6a3^{tm1(Dat-cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expession or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdDhl:DH

Produced in:

The Netherlands

Research use:

Auditory Studies, Immunology

Strain:

HsdHaz:(DB) SPF

Produced in:

U.S.

Research use:

General studies, Immunology, Neuroscience, Pharmacology, Teratology, Toxicology

Strain:

HsdSage:SD-Faah^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Analgesia, Cannabinoids, Neuroscience, Nociception, Pain

Strain:

F344/NHsd Aged

Produced in:

U.S.

Research use:

Aging, Allergic encephalomyelitis, Autoimmune disease, Carcinogenicity, General studies, Oncology, Ophthalmology, Toxicology, Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Neoplasia, Neurobiology, Osteoarthritis, Renal degeneration, Reproductive senescence, Vision and hearing

Strain:

F344/NHsd

Produced in:

U.S.

Research use:

Aging, Allergic encephalomyelitis, Autoimmune disease, Carcinogenicity, General studies, Oncology, Ophthalmology, Toxicology

Strain:

HsdSage: SD-Fmr1-/null^tm1Sage, HsdSage:SD-Fmr1+/-^tm1Sage, HsdSage:SD-Fmr1^tm1Sage

Produced in:

U.S.

Research use:

Autism, Fragile x syndrome, Neuroscience, Autism (ASD), Fragile X syndrome, Neuroscience

Strain:

FVB/NHan^®Hsd, FVB/NHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Transgenic model development

Strain:

HsdSage:SD-Gabrb3^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Epilepsy, Neuroscience, Prader-Willi syndrome

Strain:

HsdHan^®:AURA

Produced in:

U.S.

Research use:

Behavior, Carcinogenicity, COVID-19, General studies, Infectious disease, Metabolism, Oncology, Toxicology, Hibernation, Hypercholesterolemia, Syrian Hamster Embryo (SHE) Cell Transformation Assay

Strain:

HsdSage:SD-ApoE2^{tm1(hApoE2)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

Strain:

HsdSage:SD-ApoE3^{tm1(hApoE3)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

Strain:

HsdSage:SD-ApoE4^{tm1(hApoE4)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Alzheimer's disease, Neurodegenerative diseases, Neuroscience

Strain:

HsdHot:Holtzman^® SD^®

Produced in:

U.S.

Research use:

General studies, Neurology, Oncology, Reproduction, Teratology, Toxicology

Strain:

Hsd:ICR (CD-1^®)

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Aging, COVID-19, General studies, Infectious disease, Oncology, Teratology, Toxicology, Vaccines

Strain:

HsdSage:SD-Ldlr^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis- Cholesterol transportation, Hypertension, Insulin resistant, Lipoprotein, Metabolism (Triglyceride - Cholesterol), Obesity, Type II diabetes

Strain:

HsdSage:SD-Lep^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Artery disease, Atherogenesis, Atherosclerosis, Cardiovascular, Diabetes, HypertensionInsulin resistance, Lipoprotein/Cholesterol transportation, Metabolism (Triglyceride/Cholesterol), Obesity, Type II diabetes

Strain:

LEW/Han^®Hsd, LEW/SsNHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

General studies, Immunology, Oncology, Transplantation, Adjuvant-induced arthritis, Experimental allergic encephalomyelitis

Strain:

HsdSage:SD-Lgals1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdOla:LH

Produced in:

U.K., The Netherlands

Research use:

Behavior

Strain:

HsdBlu:LE

Produced in:

U.S.

Research use:

Behavior, Diet induced obesity, Diet/Obesity, General studies, Metabolism, Nutrition

Strain:

HsdSage:LE-Lrrk1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Strain:

HsdSage:LE-Lrrk1/Lrrk2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Strain:

HsdSage:LE-Lrrk^tm1Sage

Produced in:

U.S.

Research use:

Neuroscience, Neuronal apoptosis, Parkinson's disease

Strain:

HsdSage:SD-Mdr1a^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mdr1a^tm1SageMdr1b^tm1Sage

Produced in:

U.S.

Research use:

Drug-drug interactions, ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mdr1a^tm1SageAbcg2^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mecp2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Rett syndrome, Autism (ASD), Cognition, Neuroscience, Rett Syndrome

Strain:

HsdSage:SD-Met^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Autoimmune disorders, Neuroscience, Synaptic Plasticity

Strain:

HsdSage:SD-Grm5^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Anxiety, Autism (ASD), Cognition, Fragile X syndrome, Pain, Schizophrenia

Strain:

HsdSage:SD-Abcc1a^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Drug metabolism, Drug resistance, Drug transporter, Studying excretion pathways in cancer

Strain:

HsdSage:SD-Abcc2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Tissue distribution, DMPKPK/PDFormulation, Drug transporter, Dubin-Johnson syndrome, Efficacy Drug-drug interactions, Efflux assays, Tissue distribution

Strain:

Hsd:ND4

Produced in:

U.S.

Research use:

Infectious disease, Pain and neuroscience, Retinal ischemia research, Toxicology

Strain:

HsdSage:SD-Nrxn1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Schizophrenia, Synaptic Plasticity

Strain:

HsdSage:SD-Nlgn3^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Asperger's syndrome, Autism (ASD), Synaptic Plasticity

Strain:

HsdHra:(NZW) SPF, Hsdlf:NZW, HsdOkd:NZW

Produced in:

U.S., U.K., Israel

Research use:

Antibody production, Atherosclerosis, Behavioral and learning disabilities, Biomedical research, Cardiovascular, General studies, Immunology, Oncology, Ophthalmology, Osteology, Pharmacology, Surgical, Teratology, Toxicology, Dermatology, Renal Studies

Strain:

NIH/OlaHsd

Produced in:

U.K.

Research use:

General purpose studies

Strain:

Hsd:NIHS

Produced in:

U.S., U.K.

Research use:

General studies

Strain:

HsdCpb:NMRI-Foxn1^nu, HsdCpb:NMRI-Foxn1^nu/Foxn1⁺

Produced in:

France

Research use:

Oncology, Tumor growth, Antibody production, Autoimmune disease, Immunology, Transplantation

Strain:

HsdWin:NMRI

Produced in:

The Netherlands

Research use:

General studies, Immunology, Transplantation

Strain:

NOD.CB17-Prkdc^scid/NCrHsd

Produced in:

U.S., Israel, France

Research use:

Immunology, Oncology, Transplantation, Tumor growth

Strain:

Hsd:NSA(CF-1^®)

Produced in:

U.S.

Research use:

General studies, Surgical, Infectious disease, Toxicology

Strain:

NZB/OlaHsd

Produced in:

U.K.

Research use:

Auto-immune haemolytic-anaemia

Strain:

NZBNZWF1/OlaHsd

Produced in:

U.K.

Research use:

Develops systemic lupus erythematosis

Strain:

NZW/OlaHsd

Produced in:

U.K.

Research use:

Hybrids between NZB/OlaHsd and NZW/OlaHsd develop systemic lupus erythematosis

Strain:

HsdSage:SD-Slc22a6^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a8^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Oprm1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Addiction, Analgesia, Neuroscience, Nociception, Pain

Strain:

HsdSage:SD-Tp53^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autoimmune disease, Cancer, Hematopoiesis, Infectious disease, Oncology, Vaccine development, Xenografts

Strain:

HsdSage:SD-Ngfr^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Neuronal apoptosis, Nociception, Pain

Strain:

HsdSage:LE-Park2^tm1Sage

Produced in:

U.S.

Research use:

Neuroscience, Dopaminergic cell toxicity, Parkinson's disease

Strain:

HsdSage:LE-Park7^tm1Sage

Produced in:

U.S.

Research use:

Neuroscience, Dopaminergic cell toxicity, Parkinson's disease

Strain:

HsdSage:LE-Pvalb^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expession or deletion in PV+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Pde4b^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Bipolar disorder, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Strain:

HsdSage:LE-Pink1^tm1Sage

Produced in:

U.S.

Research use:

Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction, Parkinson's disease

Strain:

HsdSage:SD-Ppara^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Autoimmune disorders, Cell proliferation, Drug metabolism, Diabetes, Immunology, Inflammation, Lipid metabolism, Obesity, Wound healing, Xenobiotic

Strain:

HsdSage:SD-Prkdc^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Immunology, Cancer metastasis, Oncology, Tumor cell growth, Xenograft

Strain:

HsdSage:SD-Pten^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Cancer, Neuroscience, Oncology

Strain:

HsdSage:SD-Nr1i2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-Nr1i2^tm1SageNr1i3^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-NR1i2/NR1i3/AHR^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

F344-Rag1^tm1Sage/SageHsd

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Xenograft

Strain:

HsdSage:SD-Rag1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Hematopoieses, Immunology, Inflammation/Autoimmune disorders, Infectious disease, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Strain:

F344-Rag2^tm1Sage/SageHsd

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Strain:

HsdSage:SD-Rag2^tm1sage

Produced in:

U.S. Cryopreserved

Research use:

Infectious disease, Oncology, Vaccines, Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Hematopoieses, Thrombosis/Cardiac fibrosis, Vascular defects, Xenograft

Strain:

B6;129-Rag2^tm1FwaII2rg^tm1Rsky/DwlHsd

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Imaging, Immunology, Immunotherapy, Neuropathology, Oncology, Stem cells, Tumor growth, Cancer cell transplantation, Infectious disease

Strain:

HsdSage:SD-Rbfox1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neurodegenerative Disorders, Neuroscience

Strain:

M. mulatta

Produced in:

U.S.

Research use:

COVID-19, Diabetes, Immunology, Infectious disease, Neuroscience, Obesity, Pharmacology, Toxicology, Transplantation

Strain:

HsdHu:SABRA-M

Produced in:

Israel

Research use:

Behavior, General studies, Toxicology

Strain:

HsdHu:SABRA-R

Produced in:

Israel

Research use:

General studies, Pain, Toxicology

Strain:

SAMP8/TaHsd, SAMR1/TaHsd (control)

Produced in:

The Netherlands

Research use:

Accelerated senescence studies, Age-dependent disorders, Brain atrophy, Deficits in learning and memory, Emotional disorders Aging process, Geriatric pathogenesis, Hearing impairment, Hyperinflation of the lungs, Senile amyloidosis (apolipoprotein A-II), Senile osteoporosis

Strain:

C.B-17/IcrHan^®Hsd-Prkdc^scid, C.B-17/IcrHsd-Prkdc^scid

Produced in:

U.S., U.K., Israel, France

Research use:

General studies, Imaging, Immunology, Oncology, Transplantation, Tumor growth

Strain:

C.B-17/IcrHsd-Prkdc^scidLyst^bg-J

Produced in:

U.S., Israel, France

Research use:

Gene therapy, General studies, Immunology, Oncology, Transplantation, Tumor growth, Teratology

Strain:

NOD.Cg-Prkdc^scidHr^hr/NCrHsd

Produced in:

France Cryopreserved

Research use:

Oncology, Humanization applications, Imaging applications, Xenograft transplantation

Strain:

SJL/JCrHsd

Produced in:

U.S., The Netherlands, Israel

Research use:

Behavior, Immunology

Strain:

SHR/NHsd

Produced in:

U.S., U.K.

Research use:

Hypertension, Surgical, Insulin resistant

Strain:

Hsd:Sprague Dawley^® SD^® Aged

Produced in:

U.S.

Research use:

Age-associated pathology, Cardiovascular, Immune response, Longevity, Memory, Metabolism, Motor skills, Neoplasia, Neurobiology, Osteoarthritis, Renal degeneration, Reproductive senescence, Vision and hearing

Strain:

Hsd:Sprague Dawley^® SD^®

Produced in:

U.S., U.K., The Netherlands, Israel

Research use:

Aging, Cardiovascular, COVID-19, Diabetes induced obesity, Diet induced obesity, General studies, Immunology, Infectious disease, Neuroscience, Nutrition, Oncology, Preclincial (PK/PD), Reproductive, Surgical, Teratology, Toxicology

Strain:

HsdSage: LE-SSt.Cre^tm1Sage

Produced in:

U.S.

Research use:

Cre Tool for conditional expession or deletion in SST+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Tbx21^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:LE-Rosa26^{tm1(tdTomato)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Tomato fluorescence, Expression of td, Optogenetics, Tomato fluorescence when Cre-recombinase is introduced

Strain:

HsdOla:TO

Produced in:

U.K.

Research use:

General purpose

Strain:

HsdSage:LE-Tph2^{tm1(T2A-Cre)Sage}

Produced in:

U.S.

Research use:

Cre Tool for conditional expession or deletion in Tph2+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Trpv1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Cannabinoids, Nociception, Pain, Thermoregulation

Strain:

HsdSage:SD-TH^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expession or deletion in Th+ neurons, DREADD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage:LE-VGAT^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Cre Tool for conditional expession or deletion in VGAT+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:LE-VIP^{tm1(T2A-Cre)Sage}

Produced in:

U.S.

Research use:

Cre Tool for conditional expession or deletion in VIP+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

WF/NHsd

Produced in:

U.S.

Research use:

Oncology, Immunology, Leukemia, Transplantation

Strain:

RccHan^®:WIST

Produced in:

U.S., U.K., The Netherlands

Research use:

Aging, General studies, Oncology, Preclincial (PK/PD), Surgical, Teratology, Toxicology

Strain:

WKY/NHsd

Produced in:

U.S., U.K.

Research use:

Immunology, Inbred, normotensive control for SHR rat

Strain:

Hsd:WI

Produced in:

U.S.

Research use:

General studies, Aging, Nutrition, Oncology, Teratology

Strain:

HsdCpb:WU

Produced in:

The Netherlands

Research use:

Aging, General purpose model, Nutrition, Oncology, Teratology

Strain:

HsdHlr:ZUCKER-Lepr^fa, HsdHlr:ZUCKER-Lepr^fa/Lepr⁺-(Lean), HsdHlr:ZUCKER-Lepr⁺-(Lean)

Produced in:

U.S.

Research use:

Cardiovascular, Diabetes type 2, General studies, Obesity, Surgical