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    5Ht3a-Cre knockin rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Cre Tool for conditional expression or deletion in 5HT3a+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

    AHR knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

    Alpha-Synuclein A53T SNCA knockin rats

    Produced in:

    U.S.

    Research use:

    Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

    Alpha-Synuclein-SNCA knockout rats

    Produced in:

    U.S.

    Research use:

    Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

    ApoE knockout rats

    Produced in:

    U.S.

    Research use:

    Atherosclerosis, Neuroscience, Alzheimer's disease, Cardiovascular, Neurodegenerative diseases, Neuroscience

    App knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Alzheimer's disease, Dementia, Memory loss, Neurodegeneration, Neuroscience, Synaptic formation and repair

    Bcrp knockout rats

    Produced in:

    U.S.

    Research use:

    ADMET, Aging, Immunotherapy, Oncology, Stem cells, Tissue distribution, Tumor growth, DMPK efflux assay, Drug-drug interactions, Drug metabolism, Drug transporter, Efficacy assay, Formulation blood brain barrier efflux, Neuroscience, Tissue distribution

    BDNF knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Neuroscience, Alzheimer's disease, Depression, Huntington's disease, Memory loss, Nerve growth and development, Neuroscience, Pain, Post-traumatic stress disorder, Schizophrenia

    BSEP knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Cholestasis, Drug-drug interactions, Drug-induced cholestasis (DIC), Drug metabolism, Drug transporter

    Cacna1c knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neurodegeneration, Social behavior, Alzheimer's disease, Autism (ASD), Dementia, Memory loss, Neuroscience, Synaptic formation and repair

    CamKIIa-Cre knockin rats

    Produced in:

    U.S.

    Research use:

    Cre Tool for conditional expression or deletion in CamKIIa+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

    CAR knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Cytochrome p450 pathways, Cholestasis, Hepatotoxicity, Drug metabolism, Xenobiotic

    CFTR knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Lung Disease, Chloride transport, Cystic Fibrosis, Lung Disease, Thiocyanide transport

    CHD8 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Autism (ASD), Neuroscience

    Chrna7 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Epilepsy, Neuronal growth and transport studies, Neuroscience, Schizophrenia

    Cntnap2 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Autism, Neuroscience, Cell adhesion, Language disorders, Synaptic Plasticity

    Cox1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Asthma, Colitis, Crohn's disease, Immunology, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vascular defects

    Cox2 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

    Disc1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Bipolar disorder, Neuronal growth and transport studies, Neuroscience, Schizophrenia

    Dopamine Transporter DAT-Cre knockin rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neuroscience, Cre Tool for conditional expession or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

    Dopamine Transporter DAT-Cre knockin rats

    Produced in:

    U.S.

    Research use:

    Neuroscience, Cre Tool for conditional expession or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

    Faah knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Analgesia, Cannabinoids, Neuroscience, Nociception, Pain

    Fmr1 knockout rats

    Produced in:

    U.S.

    Research use:

    Autism, Fragile x syndrome, Neuroscience, Autism (ASD), Fragile X syndrome, Neuroscience

    Gabrb3 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Autism (ASD), Epilepsy, Neuroscience, Prader-Willi syndrome

    hApoE2 knockin rats

    Produced in:

    U.S.

    Research use:

    Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

    hApoE3 knockin rats

    Produced in:

    U.S.

    Research use:

    Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

    hApoE4 knockin rats

    Produced in:

    U.S.

    Research use:

    Alzheimer's disease, Alzheimer's disease, Neurodegenerative diseases, Neuroscience

    Ldlr knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis- Cholesterol transportation, Hypertension, Insulin resistant, Lipoprotein, Metabolism (Triglyceride - Cholesterol), Obesity, Type II diabetes

    Leptin knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Artery disease, Atherogenesis, Atherosclerosis, Cardiovascular, Diabetes, HypertensionInsulin resistance, Lipoprotein/Cholesterol transportation, Metabolism (Triglyceride/Cholesterol), Obesity, Type II diabetes

    Lgals1 (Gal1) knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

    Lrrk1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neuronal apoptosis, Neuroscience, Parkinson's disease

    Lrrk1-Lrrk2 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neuronal apoptosis, Neuroscience, Parkinson's disease

    Lrrk2 knockout rats

    Produced in:

    U.S.

    Research use:

    Neuroscience, Neuronal apoptosis, Parkinson's disease

    Mdr1a knockout rats

    Produced in:

    U.S.

    Research use:

    ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

    Mdr1a-1b knockout rats

    Produced in:

    U.S.

    Research use:

    Drug-drug interactions, ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

    Mdr1a-Bcrp knockout rats

    Produced in:

    U.S.

    Research use:

    ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

    MeCP2 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neuroscience, Rett syndrome, Autism (ASD), Cognition, Neuroscience, Rett Syndrome

    Met knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Autism (ASD), Autoimmune disorders, Neuroscience, Synaptic Plasticity

    mGluR5 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neuroscience, Anxiety, Autism (ASD), Cognition, Fragile X syndrome, Pain, Schizophrenia

    Mrp1 knockout rats

    Produced in:

    U.S.

    Research use:

    ADMET, Drug metabolism, Drug resistance, Drug transporter, Studying excretion pathways in cancer

    Mrp2 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Tissue distribution, DMPKPK/PDFormulation, Drug transporter, Dubin-Johnson syndrome, Efficacy Drug-drug interactions, Efflux assays, Tissue distribution

    Neurexin1-Nrxn1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Autism, Neuroscience, Schizophrenia, Synaptic Plasticity

    Neuroligin 3 (Nlgn3) knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neuroscience, Asperger's syndrome, Autism (ASD), Synaptic Plasticity

    Oat1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

    Oat3 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

    Oct1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

    Oct2 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

    Oprm1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Addiction, Analgesia, Neuroscience, Nociception, Pain

    p53 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Autoimmune disease, Cancer, Hematopoiesis, Infectious disease, Oncology, Vaccine development, Xenografts

    p75NTR knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neuroscience, Analgesia, Neuronal apoptosis, Nociception, Pain

    Park2 Parkin knockout rats

    Produced in:

    U.S.

    Research use:

    Neuroscience, Dopaminergic cell toxicity, Parkinson's disease

    Park7 DJ-1 knockout rats

    Produced in:

    U.S.

    Research use:

    Neuroscience, Dopaminergic cell toxicity, Parkinson's disease

    Parvalbumin-Cre knockin rats

    Produced in:

    U.S.

    Research use:

    Neuroscience, Cre Tool for conditional expession or deletion in PV+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

    Pde4b knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Bipolar disorder, Neuronal growth and transport studies, Neuroscience, Schizophrenia

    Pink1 knockout rats (Park6)

    Produced in:

    U.S.

    Research use:

    Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction, Parkinson's disease

    Ppara knockout rats

    Produced in:

    U.S.

    Research use:

    ADMET, Autoimmune disorders, Cell proliferation, Drug metabolism, Diabetes, Immunology, Inflammation, Lipid metabolism, Obesity, Wound healing, Xenobiotic

    Prkdc knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Immunology, Cancer metastasis, Oncology, Tumor cell growth, Xenograft

    Pten knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Autism, Cancer, Neuroscience, Oncology

    PXR knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

    PXR-CAR knockout rats

    Produced in:

    U.S.

    Research use:

    ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

    PXR/CAR/AHR knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

    Rag1 knockout rats (Fischer 344)

    Produced in:

    U.S. Cryopreserved

    Research use:

    Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Xenograft

    Rag1 knockout rats (Sprague Dawley)

    Produced in:

    U.S. Cryopreserved

    Research use:

    Cancer metastasis, Hematopoieses, Immunology, Inflammation/Autoimmune disorders, Infectious disease, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

    Rag2 knockout rats (Fischer 344)

    Produced in:

    U.S. Cryopreserved

    Research use:

    Cancer metastasis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

    Rag2 knockout rats (Sprague Dawley)

    Produced in:

    U.S. Cryopreserved

    Research use:

    Infectious disease, Oncology, Vaccines, Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Hematopoieses, Thrombosis/Cardiac fibrosis, Vascular defects, Xenograft

    Rbfox1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Autism (ASD), Neurodegenerative Disorders, Neuroscience

    Sst-Cre knockin rats

    Produced in:

    U.S.

    Research use:

    Cre Tool for conditional expession or deletion in SST+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

    Tbx21 (T-beta) knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

    tdTomato reporter knockin rats

    Produced in:

    U.S.

    Research use:

    Neuroscience, Tomato fluorescence, Expression of td, Optogenetics, Tomato fluorescence when Cre-recombinase is introduced

    Tph2-Cre knockin rats

    Produced in:

    U.S.

    Research use:

    Cre Tool for conditional expession or deletion in Tph2+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

    Trpv1 knockout rats

    Produced in:

    U.S. Cryopreserved

    Research use:

    Neuroscience, Analgesia, Cannabinoids, Nociception, Pain, Thermoregulation

    Tyrosine Hydroxylase TH-Cre knockin rats

    Produced in:

    U.S.

    Research use:

    Neuroscience, Cre Tool for conditional expession or deletion in Th+ neurons, DREADD, Expression/knockout of floxed genes, Optogenetics

    Vgat-Cre knockin rats

    Produced in:

    U.S.

    Research use:

    Cre Tool for conditional expession or deletion in VGAT+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

    VIP-Cre knockin rats

    Produced in:

    U.S.

    Research use:

    Cre Tool for conditional expession or deletion in VIP+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

    Jamie<br>Naden, PhD, Scientist

    Meet Jamie
    Naden, PhD

    Scientist

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    Paul<br>Knepley, DVM, Attending Veterinarian

    Meet Paul
    Knepley, DVM

    Attending Veterinarian

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