Strain:

HsdSage:LE-5HT3a^{tm1(T2A-Cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Cre Tool for conditional expression or deletion in 5HT3a+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Ahr^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-SNCA^{tm1(SNCA-A53T)Sage}

Produced in:

U.S.

Research use:

Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Strain:

HsdSage:SD-SCNA^tm1Sage

Produced in:

U.S.

Research use:

Dopaminergic cell toxicity, Neuroscience, Parkinson's disease

Strain:

HsdSage:SD-ApoE^tm1Sage

Produced in:

U.S.

Research use:

Atherosclerosis, Neuroscience, Alzheimer's disease, Cardiovascular, Neurodegenerative diseases, Neuroscience

Strain:

HsdSage:SD-App^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Alzheimer's disease, Dementia, Memory loss, Neurodegeneration, Neuroscience, Synaptic formation and repair

Strain:

HsdSage:SD-Abcg2^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Aging, Immunotherapy, Oncology, Stem cells, Tissue distribution, Tumor growth, DMPK efflux assay, Drug-drug interactions, Drug metabolism, Drug transporter, Efficacy assay, Formulation blood brain barrier efflux, Neuroscience, Tissue distribution

Strain:

HsdSage:SD-Bdnf^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Neuroscience, Alzheimer's disease, Depression, Huntington's disease, Memory loss, Nerve growth and development, Neuroscience, Pain, Post-traumatic stress disorder, Schizophrenia

Strain:

HsdSage:SD-Abcb11^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Drug-drug interactions, Drug-induced cholestasis (DIC), Drug metabolism, Drug transporter

Strain:

HsdSage:SD-Cacna1c^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neurodegeneration, Social behavior, Alzheimer's disease, Autism (ASD), Dementia, Memory loss, Neuroscience, Synaptic formation and repair

Strain:

HsdSage:LE-CAMKIIA^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Cre Tool for conditional expression or deletion in CamKIIa+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-NR1I3^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cytochrome p450 pathways, Cholestasis, Hepatotoxicity, Drug metabolism, Xenobiotic

Strain:

HsdSage:SD-Cftr^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Lung Disease, Chloride transport, Cystic Fibrosis, Lung Disease, Thiocyanide transport

Strain:

HsdSage:SD-CHD8^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neuroscience

Strain:

HsdSage:SD-Chrna7^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Epilepsy, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Strain:

HsdSage:SD-Cntnap2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Cell adhesion, Language disorders, Synaptic Plasticity

Strain:

HsdSage:SD-Cox1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:SD-Cox2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:SD-Disc1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Bipolar disorder, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Strain:

HsdSage:SD-Slc6a3^{tm1(Dat-cre)Sage}

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Cre Tool for conditional expession or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage: LE-Slc6a3^{tm1(Dat-cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expession or deletion in dopaminergic neurons, DREDD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage:SD-Faah^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Analgesia, Cannabinoids, Neuroscience, Nociception, Pain

Strain:

HsdSage: SD-Fmr1-/null^tm1Sage, HsdSage:SD-Fmr1+/-^tm1Sage, HsdSage:SD-Fmr1^tm1Sage

Produced in:

U.S.

Research use:

Autism, Fragile x syndrome, Neuroscience, Autism (ASD), Fragile X syndrome, Neuroscience

Strain:

HsdSage:SD-Gabrb3^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Epilepsy, Neuroscience, Prader-Willi syndrome

Strain:

HsdSage:SD-ApoE2^{tm1(hApoE2)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

Strain:

HsdSage:SD-ApoE3^{tm1(hApoE3)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Dopaminergic cell toxicity, Neuroscience

Strain:

HsdSage:SD-ApoE4^{tm1(hApoE4)Sage}

Produced in:

U.S.

Research use:

Alzheimer's disease, Alzheimer's disease, Neurodegenerative diseases, Neuroscience

Strain:

HsdSage:SD-Ldlr^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cardiovascular, Artery disease, Atherogenesis, Atherosclerosis- Cholesterol transportation, Hypertension, Insulin resistant, Lipoprotein, Metabolism (Triglyceride - Cholesterol), Obesity, Type II diabetes

Strain:

HsdSage:SD-Lep^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Artery disease, Atherogenesis, Atherosclerosis, Cardiovascular, Diabetes, HypertensionInsulin resistance, Lipoprotein/Cholesterol transportation, Metabolism (Triglyceride/Cholesterol), Obesity, Type II diabetes

Strain:

HsdSage:SD-Lgals1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:LE-Lrrk1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Strain:

HsdSage:LE-Lrrk1/Lrrk2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuronal apoptosis, Neuroscience, Parkinson's disease

Strain:

HsdSage:LE-Lrrk^tm1Sage

Produced in:

U.S.

Research use:

Neuroscience, Neuronal apoptosis, Parkinson's disease

Strain:

HsdSage:SD-Mdr1a^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mdr1a^tm1SageMdr1b^tm1Sage

Produced in:

U.S.

Research use:

Drug-drug interactions, ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mdr1a^tm1SageAbcg2^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Blood brain barrier efflux, DMPK assay, Drug metabolism, Drug resistance, Drug transporter, Efficacy, Formulation drug-drug interactions, Neurotoxicology, PK-PD efflux assay

Strain:

HsdSage:SD-Mecp2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Rett syndrome, Autism (ASD), Cognition, Neuroscience, Rett Syndrome

Strain:

HsdSage:SD-Met^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Autoimmune disorders, Neuroscience, Synaptic Plasticity

Strain:

HsdSage:SD-Grm5^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Anxiety, Autism (ASD), Cognition, Fragile X syndrome, Pain, Schizophrenia

Strain:

HsdSage:SD-Abcc1a^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Drug metabolism, Drug resistance, Drug transporter, Studying excretion pathways in cancer

Strain:

HsdSage:SD-Abcc2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Tissue distribution, DMPKPK/PDFormulation, Drug transporter, Dubin-Johnson syndrome, Efficacy Drug-drug interactions, Efflux assays, Tissue distribution

Strain:

HsdSage:SD-Nrxn1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Neuroscience, Schizophrenia, Synaptic Plasticity

Strain:

HsdSage:SD-Nlgn3^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Asperger's syndrome, Autism (ASD), Synaptic Plasticity

Strain:

HsdSage:SD-Slc22a6^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a8^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Slc22a2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Drug-drug interactions, Drug metabolism, Drug transporter, Hepatotoxicity

Strain:

HsdSage:SD-Oprm1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Addiction, Analgesia, Neuroscience, Nociception, Pain

Strain:

HsdSage:SD-Tp53^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autoimmune disease, Cancer, Hematopoiesis, Infectious disease, Oncology, Vaccine development, Xenografts

Strain:

HsdSage:SD-Ngfr^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Neuronal apoptosis, Nociception, Pain

Strain:

HsdSage:LE-Park2^tm1Sage

Produced in:

U.S.

Research use:

Neuroscience, Dopaminergic cell toxicity, Parkinson's disease

Strain:

HsdSage:LE-Park7^tm1Sage

Produced in:

U.S.

Research use:

Neuroscience, Dopaminergic cell toxicity, Parkinson's disease

Strain:

HsdSage:LE-Pvalb^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expession or deletion in PV+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Pde4b^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Bipolar disorder, Neuronal growth and transport studies, Neuroscience, Schizophrenia

Strain:

HsdSage:LE-Pink1^tm1Sage

Produced in:

U.S.

Research use:

Neuroscience, Parkinson's disease, Stress-induced neurological dysfunction, Parkinson's disease

Strain:

HsdSage:SD-Ppara^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Autoimmune disorders, Cell proliferation, Drug metabolism, Diabetes, Immunology, Inflammation, Lipid metabolism, Obesity, Wound healing, Xenobiotic

Strain:

HsdSage:SD-Prkdc^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Immunology, Cancer metastasis, Oncology, Tumor cell growth, Xenograft

Strain:

HsdSage:SD-Pten^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism, Cancer, Neuroscience, Oncology

Strain:

HsdSage:SD-Nr1i2^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-Nr1i2^tm1SageNr1i3^tm1Sage

Produced in:

U.S.

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

HsdSage:SD-NR1i2/NR1i3/AHR^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

ADMET, Cholestasis, Cytochrome p450 pathways, Drug metabolism, Hepatotoxicity, Xenobiotic

Strain:

F344-Rag1^tm1Sage/SageHsd

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Xenograft

Strain:

HsdSage:SD-Rag1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Hematopoieses, Immunology, Inflammation/Autoimmune disorders, Infectious disease, Oncology, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Strain:

F344-Rag2^tm1Sage/SageHsd

Produced in:

U.S. Cryopreserved

Research use:

Cancer metastasis, Inflammation/Autoimmune disorders, Thrombosis/Cardiac fibrosis, Vaccine development, Vascular defects, Xenograft

Strain:

HsdSage:SD-Rag2^tm1sage

Produced in:

U.S. Cryopreserved

Research use:

Infectious disease, Oncology, Vaccines, Cancer metastasis, Immunology, Inflammation/Autoimmune disorders, Hematopoieses, Thrombosis/Cardiac fibrosis, Vascular defects, Xenograft

Strain:

HsdSage:SD-Rbfox1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Autism (ASD), Neurodegenerative Disorders, Neuroscience

Strain:

HsdSage: LE-SSt.Cre^tm1Sage

Produced in:

U.S.

Research use:

Cre Tool for conditional expession or deletion in SST+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Tbx21^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Asthma, Colitis, Crohn's disease, Immunology, Inflammation/Autoimmune disorders, Multiple sclerosis, Oncology, Platelet defects/Platelet aggregation, Renal dysplasia, Rheumatoid arthritis, Thrombosis/Cardiac fibrosis, Vascular defects

Strain:

HsdSage:LE-Rosa26^{tm1(tdTomato)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Tomato fluorescence, Expression of td, Optogenetics, Tomato fluorescence when Cre-recombinase is introduced

Strain:

HsdSage:LE-Tph2^{tm1(T2A-Cre)Sage}

Produced in:

U.S.

Research use:

Cre Tool for conditional expession or deletion in Tph2+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:SD-Trpv1^tm1Sage

Produced in:

U.S. Cryopreserved

Research use:

Neuroscience, Analgesia, Cannabinoids, Nociception, Pain, Thermoregulation

Strain:

HsdSage:SD-TH^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Neuroscience, Cre Tool for conditional expession or deletion in Th+ neurons, DREADD, Expression/knockout of floxed genes, Optogenetics

Strain:

HsdSage:LE-VGAT^{tm1(IRES-Cre)Sage}

Produced in:

U.S.

Research use:

Cre Tool for conditional expession or deletion in VGAT+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics

Strain:

HsdSage:LE-VIP^{tm1(T2A-Cre)Sage}

Produced in:

U.S.

Research use:

Cre Tool for conditional expession or deletion in VIP+ neurons, Expression/knockout of floxed genes, Neuroscience, Optogenetics