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Lewis inbred rat

LOCATION

Characteristics / Husbandry

  • Coat: Albino
  • Docile disposition
  • Litter average: 7.5
  • Haplotype: RT1l
  • Inbred recipient for several congenic strains
  • Increased levels of serum thyroxine, insulin, and growth hormone
  • Susceptible to induction of autoimmune disease
Oncology
Behaviour
General Studies
Arthritis
Transplantation
Immunology
Adjuvant-induced arthritis
Experimental allergic encephalomyelitis
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Inbreeding of the Lewis rat is begun by Dr. Margaret Lewis from a Wistar stock. In 1924, at F20 to Aptekman and Bogdon. In 1958, at F31 to Silvers, who distributed this strain subsequently.

LEW/SsNHsd rats were descended from a nucleus colony obtained from the National Institutes of Health, Bethesda, Maryland USA. Harlan became Envigo in 2015.

Order Code: 017

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