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SCID/beige mice Related Publications

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Abelson, S., Shamai, Y., Berger, L., Shouval, R., Skorecki, K., & Tzukerman, M. (2012). Intratumoral heterogeneity in the self-renewal and tumorigenic differentiation of ovarian cancer. Stem Cells (Dayton, Ohio), 30(3), 415-424. doi:10.1002/stem.1029 [doi] Read Publication

Agu, C. A., Klein, R., Schwab, S., Konig-Schuster, M., Kodajova, P., Ausserlechner, M., . . . Hohenadl, C. (2006). The cytotoxic activity of the bacteriophage lambda-holin protein reduces tumour growth rates in mammary cancer cell xenograft models. The Journal of Gene Medicine, 8(2), 229-241. doi:10.1002/jgm.833 [doi] Read Publication

Ahmadian Baghbaderani, B., Tian, X., Scotty Cadet, J., Shah, K., Walde, A., Tran, H., . . . Fellner, T. (2016). A newly defined and xeno-free culture medium supports every-other-day medium replacement in the generation and long-term cultivation of human pluripotent stem cells. PloS One, 11(9), e0161229. doi:10.1371/journal.pone.0161229 [doi] Read Publication

Amendola, D., Nardella, M., Guglielmi, L., Cerquetti, L., Carico, E., Alesi, V., . . . Bucci, B. (2014). Human placenta-derived neurospheres are susceptible to transformation after extensive in vitro expansion. Stem Cell Research & Therapy, 5(2), 55. doi:10.1186/scrt444 [doi] Read Publication

Andersen, C. L., Sikora, M. J., Boisen, M. M., Ma, T., Christie, A., Tseng, G., . . . Oesterreich, S. (2017). Active estrogen receptor-alpha signaling in ovarian cancer models and clinical specimens. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(14), 3802-3812. doi:10.1158/1078-0432.CCR-16-1501 [doi] Read Publication

Berger, L., Shamai, Y., Skorecki, K. L., & Tzukerman, M. (2016). Tumor specific recruitment and reprogramming of mesenchymal stem cells in tumorigenesis. Stem Cells (Dayton, Ohio), 34(4), 1011-1026. doi:10.1002/stem.2269 [doi] Read Publication

Blouw, B., Patel, M., Iizuka, S., Abdullah, C., You, W. K., Huang, X., . . . Courtneidge, S. A. (2015). The invadopodia scaffold protein Tks5 is required for the growth of human breast cancer cells in vitro and in vivo. PloS One, 10(3), e0121003. doi:10.1371/journal.pone.0121003 [doi] Read Publication

Blum, B., & Benvenisty, N. (2007). Clonal analysis of human embryonic stem cell differentiation into teratomas. Stem Cells (Dayton, Ohio), 25(8), 1924-1930. doi:2007-0073 [pii] Read Publication

Butler, K. A., Hou, X., Becker, M. A., Zanfagnin, V., Enderica-Gonzalez, S., Visscher, D., . . . Weroha, S. J. (2017). Prevention of human lymphoproliferative tumor formation in ovarian cancer patient-derived xenografts. Neoplasia (New York, N.Y.), 19(8), 628-636. doi:S1476-5586(17)30079-9 [pii] Read Publication

Capello, M., Ferri-Borgogno, S., Riganti, C., Chattaragada, M. S., Principe, M., Roux, C., . . . Novelli, F. (2016). Targeting the warburg effect in cancer cells through ENO1 knockdown rescues oxidative phosphorylation and induces growth arrest. Oncotarget, 7(5), 5598-5612. doi:10.18632/oncotarget.6798 [doi] Read Publication

Debeb, B. G., Lacerda, L., Anfossi, S., Diagaradjane, P., Chu, K., Bambhroliya, A., . . . Woodward, W. A. (2016). miR-141-mediated regulation of brain metastasis from breast cancer. Journal of the National Cancer Institute, 108(8), 10.1093/jnci/djw026. Print 2016 Aug. doi:10.1093/jnci/djw026 [doi] Read Publication

Elsner, L., Muppala, V., Gehrmann, M., Lozano, J., Malzahn, D., Bickeboller, H., . . . Dressel, R. (2007). The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands. Journal of Immunology (Baltimore, Md.: 1950), 179(8), 5523-5533. doi:179/8/5523 [pii] Read Publication

Kamarajugadda, S., Stemboroski, L., Cai, Q., Simpson, N. E., Nayak, S., Tan, M., & Lu, J. (2012). Glucose oxidation modulates anoikis and tumor metastasis. Molecular and Cellular Biology, 32(10), 1893-1907. doi:10.1128/MCB.06248-11 [doi] Read Publication

Kanabur, P., Guo, S., Simonds, G. R., Kelly, D. F., Gourdie, R. G., Verbridge, S. S., & Sheng, Z. (2016). Patient-derived glioblastoma stem cells respond differentially to targeted therapies. Oncotarget, 7(52), 86406-86419. doi:10.18632/oncotarget.13415 [doi] Read Publication

Kim, S. E., Zhang, L., Ma, K., Riegman, M., Chen, F., Ingold, I., . . . Overholtzer, M. (2016). Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth. Nature Nanotechnology, 11(11), 977-985. doi:10.1038/nnano.2016.164 [doi] Read Publication

Nehil, M., Paquette, J., Tokuyasu, T., & McCormick, F. (2014). High mobility group box 1 promotes tumor cell migration through epigenetic silencing of semaphorin 3A. Oncogene, 33(44), 5151-5162. doi:10.1038/onc.2013.459 [doi] Read Publication

Orian-Rousseau, V., Mink, S., Mengwasser, J., HogenEsch, H., Guo, F., Thies, W. G., . . . Ponta, H. (2005). Genes upregulated in a metastasizing human colon carcinoma cell line. International Journal of Cancer.Journal International Du Cancer, 113(5), 699-705. doi:10.1002/ijc.20644 [doi] Read Publication

Rhodes, L. V., Muir, S. E., Elliott, S., Guillot, L. M., Antoon, J. W., Penfornis, P., . . . Burow, M. E. (2010). Adult human mesenchymal stem cells enhance breast tumorigenesis and promote hormone independence. Breast Cancer Research and Treatment, 121(2), 293-300. doi:10.1007/s10549-009-0458-2 [doi] Read Publication

Tzukerman, M., Rosenberg, T., Reiter, I., Ben-Eliezer, S., Denkberg, G., Coleman, R., . . . Skorecki, K. (2006). The influence of a human embryonic stem cell-derived microenvironment on targeting of human solid tumor xenografts. Cancer Research, 66(7), 3792-3801. doi:66/7/3792 [pii] Read Publication

Urbinati, G., Ali, H. M., Rousseau, Q., Chapuis, H., Desmaele, D., Couvreur, P., & Massaad-Massade, L. (2015). Antineoplastic effects of siRNA against TMPRSS2-ERG junction oncogene in prostate cancer. PloS One, 10(5), e0125277. doi:10.1371/journal.pone.0125277 [doi] Read Publication

Wolfe, A. R., Debeb, B. G., Lacerda, L., Larson, R., Bambhroliya, A., Huang, X., . . . Woodward, W. A. (2015). Simvastatin prevents triple-negative breast cancer metastasis in pre-clinical models through regulation of FOXO3a. Breast Cancer Research and Treatment, 154(3), 495-508. doi:10.1007/s10549-015-3645-3 [doi] Read Publication

Abelson, S., Shamai, Y., Berger, L., Skorecki, K., & Tzukerman, M. (2013). Niche-dependent gene expression profile of intratumoral heterogeneous ovarian cancer stem cell populations. PloS One, 8(12), e83651. doi:10.1371/journal.pone.0083651 [doi] Read Publication

Abrams, T., Connor, A., Fanton, C., Cohen, S. B., Huber, T., Miller, K., . . . Schleyer, S. C. (2018). Preclinical antitumor activity of a novel anti-c-KIT antibody-drug conjugate against mutant and wild-type c-KIT-positive solid tumors. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 24(17), 4297-4308. doi:10.1158/1078-0432.CCR-17-3795 [doi] Read Publication

Adepoju, L. J., & Geiger, J. D. (2010). Antitumor activity of polyuridylic acid in human soft tissue and bone sarcomas. The Journal of Surgical Research, 164(1), e107-14. doi:10.1016/j.jss.2010.05.038 [doi] Read Publication

Bailey, K. M., Cornnell, H. H., Ibrahim-Hashim, A., Wojtkowiak, J. W., Hart, C. P., Zhang, X., . . . Gillies, R. J. (2014). Evaluation of the "steal" phenomenon on the efficacy of hypoxia activated prodrug TH-302 in pancreatic cancer. PloS One, 9(12), e113586. doi:10.1371/journal.pone.0113586 [doi] Read Publication

Bartalucci, N., Tozzi, L., Bogani, C., Martinelli, S., Rotunno, G., Villeval, J. L., & Vannucchi, A. M. (2013). Co-targeting the PI3K/mTOR and JAK2 signalling pathways produces synergistic activity against myeloproliferative neoplasms. Journal of Cellular and Molecular Medicine, 17(11), 1385-1396. doi:10.1111/jcmm.12162 [doi] Read Publication

Cody, J. J., Rivera, A. A., Lyons, G. R., Yang, S. W., Wang, M., Ashley, J. W., . . . Douglas, J. T. (2013). Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model. Laboratory Investigation; a Journal of Technical Methods and Pathology, 93(3), 268-278. doi:10.1038/labinvest.2012.179 [doi] Read Publication

Czardybon, W., Windak, R., Golas, A., Galezowski, M., Sabiniarz, A., Dolata, I., . . . Brzozka, K. (2018). A novel, dual pan-PIM/FLT3 inhibitor SEL24 exhibits broad therapeutic potential in acute myeloid leukemia. Oncotarget, 9(24), 16917-16931. doi:10.18632/oncotarget.24747 [doi] Read Publication

Davila-Gonzalez, D., Choi, D. S., Rosato, R. R., Granados-Principal, S. M., Kuhn, J. G., Li, W. F., . . . Chang, J. C. (2018). Pharmacological inhibition of NOS activates ASK1/JNK pathway augmenting docetaxel-mediated apoptosis in triple-negative breast cancer. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 24(5), 1152-1162. doi:10.1158/1078-0432.CCR-17-1437 [doi] Read Publication

Debeb, B. G., Lacerda, L., Xu, W., Larson, R., Solley, T., Atkinson, R., . . . Woodward, W. A. (2012). Histone deacetylase inhibitors stimulate dedifferentiation of human breast cancer cells through WNT/beta-catenin signaling. Stem Cells (Dayton, Ohio), 30(11), 2366-2377. doi:10.1002/stem.1219 [doi] Read Publication

Ding, H., Peterson, K. L., Correia, C., Koh, B., Schneider, P. A., Nowakowski, G. S., & Kaufmann, S. H. (2017). Histone deacetylase inhibitors interrupt HSP90*RASGRP1 and HSP90*CRAF interactions to upregulate BIM and circumvent drug resistance in lymphoma cells. Leukemia, 31(7), 1593-1602. doi:10.1038/leu.2016.357 [doi] Read Publication

Egberts, J. H., Cloosters, V., Noack, A., Schniewind, B., Thon, L., Klose, S., . . . Trauzold, A. (2008). Anti-tumor necrosis factor therapy inhibits pancreatic tumor growth and metastasis. Cancer Research, 68(5), 1443-1450. doi:10.1158/0008-5472.CAN-07-5704 [doi] Read Publication

Egberts, J. H., Schniewind, B., Patzold, M., Kettler, B., Tepel, J., Kalthoff, H., & Trauzold, A. (2008). Dexamethasone reduces tumor recurrence and metastasis after pancreatic tumor resection in SCID mice. Cancer Biology & Therapy, 7(7), 1044-1050. doi:6099 [pii] Read Publication

Egberts, J. H., Schniewind, B., Sipos, B., Hinz, S., Kalthoff, H., & Tepel, J. (2007). Superiority of extended neoadjuvant chemotherapy with gemcitabine in pancreatic cancer: A comparative analysis in a clinically adapted orthotopic xenotransplantation model in SCID beige mice. Cancer Biology & Therapy, 6(8), 1227-1232. doi:4414 [pii] Read Publication

Gatto, F., Redaelli, D., Salvade, A., Marzorati, S., Sacchetti, B., Ferina, C., . . . Serafini, M. (2012). Hurler disease bone marrow stromal cells exhibit altered ability to support osteoclast formation. Stem Cells and Development, 21(9), 1466-1477. doi:10.1089/scd.2011.0555 [doi] Read Publication

Gill, S. E., Zhang, Q., Keeney, G. L., Cliby, W. A., & Weroha, S. J. (2017). Investigation of factors affecting the efficacy of 3C23K, a human monoclonal antibody targeting MISIIR. Oncotarget, 8(49), 85214-85223. doi:10.18632/oncotarget.19620 [doi] Read Publication

Glaser, G., Weroha, S. J., Becker, M. A., Hou, X., Enderica-Gonzalez, S., Harrington, S. C., & Haluska, P. (2015). Conventional chemotherapy and oncogenic pathway targeting in ovarian carcinosarcoma using a patient-derived tumorgraft. PloS One, 10(5), e0126867. doi:10.1371/journal.pone.0126867 [doi] Read Publication

Goswami, M. T., Reka, A. K., Kurapati, H., Kaza, V., Chen, J., Standiford, T. J., & Keshamouni, V. G. (2015). Regulation of complement-dependent cytotoxicity by TGF-beta-induced epithelial-mesenchymal transition. Oncogene, doi:10.1038/onc.2015.258 [doi] Read Publication

Hiriyan, J., Shivarudraiah, P., Gavara, G., Annamalai, P., Natesan, S., Sambasivam, G., & Sukumaran, S. K. (2015). Discovery of PAT-1102, a novel, potent and orally active histone deacetylase inhibitor with antitumor activity in cancer mouse models. Anticancer Research, 35(1), 229-237. doi:35/1/229 [pii] Read Publication

Hong, S. H., Youbi, S. E., Hong, S. P., Kallakury, B., Monroe, P., Erkizan, H. V., . . . Toretsky, J. A. (2014). Pharmacokinetic modeling optimizes inhibition of the 'undruggable' EWS-FLI1 transcription factor in ewing sarcoma. Oncotarget, 5(2), 338-350. doi:1495 [pii] Read Publication

Huang, K. L., Li, S., Mertins, P., Cao, S., Gunawardena, H. P., Ruggles, K. V., . . . Ding, L. (2017). Proteogenomic integration reveals therapeutic targets in breast cancer xenografts. Nature Communications, 8, 14864. doi:10.1038/ncomms14864 [doi] Read Publication

Ingallina, C., Costa, P. M., Ghirga, F., Klippstein, R., Wang, J. T., Berardozzi, S., . . . Al-Jamal, K. T. (2017). Polymeric glabrescione B nanocapsules for passive targeting of hedgehog-dependent tumor therapy in vitro. Nanomedicine (London, England), 12(7), 711-728. doi:10.2217/nnm-2016-0388 [doi] Read Publication

Katz, E., Skorecki, K., & Tzukerman, M. (2009). Niche-dependent tumorigenic capacity of malignant ovarian ascites-derived cancer cell subpopulations. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 15(1), 70-80. doi:10.1158/1078-0432.CCR-08-1233 [doi] Read Publication

Kelly, R. K., Olson, D. L., Sun, Y., Wen, D., Wortham, K. A., Antognetti, G., . . . Sanicola, M. (2011). An antibody-cytotoxic conjugate, BIIB015, is a new targeted therapy for cripto positive tumours. European Journal of Cancer (Oxford, England : 1990), 47(11), 1736-1746. doi:10.1016/j.ejca.2011.02.023 [doi] Read Publication

Key, J., Aryal, S., Gentile, F., Ananta, J. S., Zhong, M., Landis, M. D., & Decuzzi, P. (2013). Engineering discoidal polymeric nanoconstructs with enhanced magneto-optical properties for tumor imaging. Biomaterials, 34(21), 5402-5410. doi:10.1016/j.biomaterials.2013.03.078 [doi] Read Publication

Kurdow, R., Boehle, A. S., Haye, S., Boenicke, L., Schniewind, B., Dohrmann, P., & Kalthoff, H. (2002). Ganciclovir prodrug therapy is effective in a murine xenotransplant model of human lung cancer. The Annals of Thoracic Surgery, 73(3), 905-910. Read Publication

Le Moigne, R., Aftab, B. T., Djakovic, S., Dhimolea, E., Valle, E., Murnane, M., . . . Rolfe, M. (2017). The p97 inhibitor CB-5083 is a unique disrupter of protein homeostasis in models of multiple myeloma. Molecular Cancer Therapeutics, 16(11), 2375-2386. doi:10.1158/1535-7163.MCT-17-0233 [doi] Read Publication

Lee, F. Y., Smykla, R., Johnston, K., Menard, K., McGlinchey, K., Peterson, R. W., . . . Kramer, R. (2009). Preclinical efficacy spectrum and pharmacokinetics of ixabepilone. Cancer Chemotherapy and Pharmacology, 63(2), 201-212. doi:10.1007/s00280-008-0727-5 [doi] Read Publication

Li, X., Wu, J. B., Li, Q., Shigemura, K., Chung, L. W., & Huang, W. C. (2016). SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-myc in prostate cancer. Oncotarget, 7(11), 12869-12884. doi:10.18632/oncotarget.7331 [doi] Read Publication

Lipnik, K., Greco, O., Scott, S., Knapp, E., Mayrhofer, E., Rosenfellner, D., . . . Hohenadl, C. (2006). Hypoxia- and radiation-inducible, breast cell-specific targeting of retroviral vectors. Virology, 349(1), 121-133. doi:S0042-6822(05)00851-2 [pii] Read Publication

Miron, T., Wilchek, M., Shvidel, L., Berrebi, A., & Arditti, F. D. (2012). S-allyl derivatives of 6-mercaptopurine are highly potent drugs against human B-CLL through synergism between 6-mercaptopurine and allicin. Leukemia Research, 36(12), 1536-1540. doi:10.1016/j.leukres.2012.08.023 [doi] Read Publication

Natoni, A., Smith, T. A. G., Keane, N., McEllistrim, C., Connolly, C., Jha, A., . . . O'Dwyer, M. E. (2017). E-selectin ligands recognised by HECA452 induce drug resistance in myeloma, which is overcome by the E-selectin antagonist, GMI-1271. Leukemia, 31(12), 2642-2651. doi:10.1038/leu.2017.123 [doi] Read Publication

Naumann, C. M., Sperveslage, J., Hamann, M. F., Leuschner, I., Weder, L., Al-Najar, A. A., . . . Kalthoff, H. (2012). Establishment and characterization of primary cell lines of squamous cell carcinoma of the penis and its metastasis. The Journal of Urology, 187(6), 2236-2242. doi:10.1016/j.juro.2012.01.035 [doi] Read Publication

Pesakhov, S., Nachliely, M., Barvish, Z., Aqaqe, N., Schwartzman, B., Voronov, E., . . . Danilenko, M. (2016). Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid. Oncotarget, 7(22), 31847-31861. doi:10.18632/oncotarget.7240 [doi] Read Publication

Potter, D. S., Galvin, M., Brown, S., Lallo, A., Hodgkinson, C. L., Blackhall, F., . . . Dive, C. (2016). Inhibition of PI3K/BMX cell survival pathway sensitizes to BH3 mimetics in SCLC. Molecular Cancer Therapeutics, 15(6), 1248-1260. doi:10.1158/1535-7163.MCT-15-0885 [doi] Read Publication

Rakhmilevich, A. L., Buhtoiarov, I. N., Malkovsky, M., & Sondel, P. M. (2008). CD40 ligation in vivo can induce T cell independent antitumor effects even against immunogenic tumors. Cancer Immunology, Immunotherapy : CII, 57(8), 1151-1160. doi:10.1007/s00262-007-0447-4 [doi] Read Publication

Reka, A. K., Kurapati, H., Narala, V. R., Bommer, G., Chen, J., Standiford, T. J., & Keshamouni, V. G. (2010). Peroxisome proliferator-activated receptor-gamma activation inhibits tumor metastasis by antagonizing Smad3-mediated epithelial-mesenchymal transition. Molecular Cancer Therapeutics, 9(12), 3221-3232. doi:10.1158/1535-7163.MCT-10-0570 [doi] Read Publication

Rzymski, T., Mikula, M., Zylkiewicz, E., Dreas, A., Wiklik, K., Golas, A., . . . Brzozka, K. (2017). SEL120-34A is a novel CDK8 inhibitor active in AML cells with high levels of serine phosphorylation of STAT1 and STAT5 transactivation domains. Oncotarget, 8(20), 33779-33795. doi:10.18632/oncotarget.16810 [doi] Read Publication

Schott, A. F., Landis, M. D., Dontu, G., Griffith, K. A., Layman, R. M., Krop, I., . . . Chang, J. C. (2013). Preclinical and clinical studies of gamma secretase inhibitors with docetaxel on human breast tumors. Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 19(6), 1512-1524. doi:10.1158/1078-0432.CCR-11-3326 [doi] Read Publication

Sobot, D., Mura, S., Rouquette, M., Vukosavljevic, B., Cayre, F., Buchy, E., . . . Couvreur, P. (2017). Circulating lipoproteins: A trojan horse guiding squalenoylated drugs to LDL-accumulating cancer cells. Molecular Therapy : The Journal of the American Society of Gene Therapy, 25(7), 1596-1605. doi:S1525-0016(17)30234-4 [pii] Read Publication

Speyer, C. L., Bukhsh, M. A., Jafry, W. S., Sexton, R. E., Bandyopadhyay, S., & Gorski, D. H. (2017). Riluzole synergizes with paclitaxel to inhibit cell growth and induce apoptosis in triple-negative breast cancer. Breast Cancer Research and Treatment, 166(2), 407-419. doi:10.1007/s10549-017-4435-x [doi] Read Publication

Stangl, S., Wortmann, A., Guertler, U., & Multhoff, G. (2006). Control of metastasized pancreatic carcinomas in SCID/beige mice with human IL-2/TKD-activated NK cells. Journal of Immunology (Baltimore, Md.: 1950), 176(10), 6270-6276. doi:176/10/6270 [pii] Read Publication

Stein, U., Walther, W., Arlt, F., Schwabe, H., Smith, J., Fichtner, I., . . . Schlag, P. M. (2009). MACC1, a newly identified key regulator of HGF-MET signaling, predicts colon cancer metastasis. Nature Medicine, 15(1), 59-67. doi:10.1038/nm.1889 [doi] Read Publication

Sukowati, C. H., Anfuso, B., Croce, L. S., & Tiribelli, C. (2015). The role of multipotent cancer associated fibroblasts in hepatocarcinogenesis. BMC Cancer, 15, 188-015-1196-y. doi:10.1186/s12885-015-1196-y [doi] Read Publication

Urbinati, G., Ali, H. M., Rousseau, Q., Chapuis, H., Desmaele, D., Couvreur, P., & Massaad-Massade, L. (2015). Antineoplastic effects of siRNA against TMPRSS2-ERG junction oncogene in prostate cancer. PloS One, 10(5), e0125277. doi:10.1371/journal.pone.0125277 [doi] Read Publication

Vallejo-Diaz, J., Olazabal-Moran, M., Cariaga-Martinez, A. E., Pajares, M. J., Flores, J. M., Pio, R., . . . Carrera, A. C. (2016). Targeted depletion of PIK3R2 induces regression of lung squamous cell carcinoma. Oncotarget, 7(51), 85063-85078. doi:10.18632/oncotarget.13195 [doi] Read Publication

van Brussel, A. S., Adams, A., Vermeulen, J. F., Oliveira, S., van der Wall, E., Mali, W. P., . . . van Bergen En Henegouwen, P. M. (2013). Molecular imaging with a fluorescent antibody targeting carbonic anhydrase IX can successfully detect hypoxic ductal carcinoma in situ of the breast. Breast Cancer Research and Treatment, 140(2), 263-272. doi:10.1007/s10549-013-2635-6 [doi] Read Publication

van de Ven, A. L., Abdollahi, B., Martinez, C. J., Burey, L. A., Landis, M. D., Chang, J. C., . . . Frieboes, H. B. (2013). Modeling of nanotherapeutics delivery based on tumor perfusion. New Journal of Physics, 15, 55004. doi:10.1088/1367-2630/15/5/055004 [doi] Read Publication

Vermeulen, J. F., van Brussel, A. S., Adams, A., Mali, W. P., van der Wall, E., van Diest, P. J., & Derksen, P. W. (2013). Near-infrared fluorescence molecular imaging of ductal carcinoma in situ with CD44v6-specific antibodies in mice: A preclinical study. Molecular Imaging and Biology : MIB : The Official Publication of the Academy of Molecular Imaging, 15(3), 290-298. doi:10.1007/s11307-012-0605-8 [doi] Read Publication

von Forstner, C., Egberts, J. H., Ammerpohl, O., Niedzielska, D., Buchert, R., Mikecz, P., . . . Brenner, W. (2008). Gene expression patterns and tumor uptake of 18F-FDG, 18F-FLT, and 18F-FEC in PET/MRI of an orthotopic mouse xenotransplantation model of pancreatic cancer. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 49(8), 1362-1370. doi:10.2967/jnumed.107.050021 [doi] Read Publication

von Karstedt, S., Conti, A., Nobis, M., Montinaro, A., Hartwig, T., Lemke, J., . . . Walczak, H. (2015). Cancer cell-autonomous TRAIL-R signaling promotes KRAS-driven cancer progression, invasion, and metastasis. Cancer Cell, 27(4), 561-573. doi:10.1016/j.ccell.2015.02.014 [doi] Read Publication

Xu, W., Lacerda, L., Debeb, B. G., Atkinson, R. L., Solley, T. N., Li, L., . . . Woodward, W. A. (2013). The antihelmintic drug pyrvinium pamoate targets aggressive breast cancer. PloS One, 8(8), e71508. doi:10.1371/journal.pone.0071508 [doi] Read Publication

Zhang, X. D., Baladandayuthapani, V., Lin, H., Mulligan, G., Li, B., Esseltine, D. W., . . . Orlowski, R. Z. (2016). Tight junction protein 1 modulates proteasome capacity and proteasome inhibitor sensitivity in multiple myeloma via EGFR/JAK1/STAT3 signaling. Cancer Cell, 29(5), 639-652. doi:S1535-6108(16)30109-X [pii] Read Publication

Zhao, N., Cao, J., Xu, L., Tang, Q., Dobrolecki, L. E., Lv, X., . . . Chen, X. (2018). Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer. The Journal of Clinical Investigation, 128(4), 1283-1299. doi:10.1172/JCI95873 [doi] Read Publication

Abu-Tayeh, H., Weidenfeld, K., Zhilin-Roth, A., Schif-Zuck, S., Thaler, S., Cotarelo, C., . . . Barkan, D. (2016). 'Normalizing' the malignant phenotype of luminal breast cancer cells via alpha(v)beta(3)-integrin. Cell Death & Disease, 7(12), e2491. doi:10.1038/cddis.2016.387 [doi] Read Publication

Boehle, A. S., Dohrmann, P., Leuschner, I., Kalthoff, H., & Henne-Bruns, D. (2000). An improved orthotopic xenotransplant procedure for human lung cancer in SCID bg mice. The Annals of Thoracic Surgery, 69(4), 1010-1015. doi:S0003-4975(00)01090-0 [pii] Read Publication

Brandt, L. P., Albers, J., Hejhal, T., Catalano, A., Wild, P. J., & Frew, I. J. (2017). Oncogenic HrasG12V expression plus knockdown of Cdkn2a using ecotropic lentiviral vectors induces high-grade endometrial stromal sarcoma. PloS One, 12(10), e0186102. doi:10.1371/journal.pone.0186102 [doi] Read Publication

Davis, D. R., Zhang, Y., Smith, R. R., Cheng, K., Terrovitis, J., Malliaras, K., . . . Marban, E. (2009). Validation of the cardiosphere method to culture cardiac progenitor cells from myocardial tissue. PloS One, 4(9), e7195. doi:10.1371/journal.pone.0007195 [doi] Read Publication

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