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NMRI nude mice


LOCATIONS

Characteristics / Husbandry

  • Coat: Albino
  • Litter Average: 7
  • The nu allele on chromosome 11 is an autosomal recessive mutation
  • Dysfunctional rudimentary thymus
  • Phenotypically hairless (sparse, intermittent hair growth possible)
  • T-cell deficient
  • B-cells function normal
  • No generation of cytotoxic effector cells
  • No graft versus host response
  • Foxn1nu/Foxn1+ heterogygotes do not show partial expression of the nu phenotype
Oncology
Tumor Cell Growth
Transplantation
Immunology
Autoimmune disease
Antibody production
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Derived from a nucleus colony obtained from the Laboratory Animals Centre, Carshalton, UK. To TNO-CPB (now Envigo) in 1972.

Order Code: 889/890

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