Envigo has a dedicated group specializing in biotransformation studies, which is underpinned by broad experience and a comprehensive knowledge in chromatographic analysis and mammalian biotransformation pathways; this includes scientists whose primary specialism is in the structural elucidation of unknowns using mass spectrometry.
- Radiochromatography with flow-through or stop-flow detection
- Off-line fraction collection into wellplates and detection using TopCount
- Thermo Q-Exactive Focus with ThermoScientific Ultimate 3000
- AB Sciex QTrap 4000 with Agilent 1200
Our scientists have extensive experience in the analysis and characterization of small and large molecules and their metabolites from radiolabelled and non-radiolabelled studies, mostly unsupported by availability of corresponding reference compounds.