In vitro safety assessment

Before you go to regulators and go to market, you need confidence that your products do no harm. At Envigo, we have more than 20 years of experience conducting in vitro safety testing and offer a comprehensive service for in vitro safety assessment of crop protection products. Additionally, should your project require it, we staff a dedicated chemical registration services group offering specialists in weight of evidence (WOE) studies, in silico evaluation and in vitro testing requirements.

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  • In vitro skin irritation (OECD 439) - EPISKIN human skin model
  • In vitro skin corrosivity (OECD 431) - EpiDerm™ human skin model
  • Eye irritation (OECD 437) - bovine corneal opacity and permeability test (BCOP)
  • Phototoxicity (OECD 432) - 3T3 NRU
  • In vitro dermal absorption (OECD 428)
  • Cytotoxicity - neutral red uptake, elution or agar overlay
  • In vitro screening assays (EPA Tier I) for endocrine disruptors
  • Direct peptide reactivity assay (DPRA) – skin sensitization

Envigo has scientists with 20+ years of experience of in vitro safety testing. Our scientists have been involved in ECVAM and ICVAM development of in vitro alternative tests and in vitro endocrine disruptor screens. Members of our team have worldwide experience and participate in international development trials coordinated by FRAME, ECVAM and ICVAM. Our experts are members of the in vitro toxicology society (IVTS) and in vitro testing industrial platform (IVTIP). The team is supported by our dedicated Envigo Regulatory Affairs Group and Chemical Registration specialists.

Meet Hyacinth Chin Sue, Expert Consultant

Meet David Arrowsmith, Regulatory Specialist

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