Envigo is a global company that is committed to helping customers realize the full potential of their products and research which contribute to enhancing the lives of people and animals, as well as protecting the environment. The value of animals in this critical research is essential for advancing our understanding of the body in health and disease and for developing new medicines and other compounds. Without animal research, we would not be able to produce the life-changing medicines that enhance and save lives across the world.

    Envigo only works with animals in research when there is no alternative method available or where research is mandated by legal or regulatory requirements. Animal research is currently mandated to:

    • Demonstrate the safety and efficacy of new medicines, for people and animals
    • Evaluate the safety of chemicals to humans, animals and the environment

    In carrying out animal research for our customers at Envigo we follow the principles of the 3Rs - Replacement, Reduction and Refinement. We ensure the 3Rs are considered at all levels of the company. This means we work with alternatives to animals whenever we can, we aim to carry out studies with the fewest number of animals possible, and we take measures to minimize any pain or distress before, during, and after experimental procedures.

    As well as research on animals, we use a range of other approaches and methods for research such as cell cultures, in vitro techniques, computer modelling, bioinformatics, high-throughput screening and clinical trials in people. We only work with animals when there is no other way of performing that research; in fact, legislation in many countries state that animal research is not permitted if an alternative non-animal method is available. In addition, we are working to develop alternative techniques that replace and reduce our need to work with animals in research.

    At Envigo, animal welfare is a top priority. We adopt a humane and compassionate approach, actively fostering a culture of care towards our animals and aim to operate to the highest professional standards. Animals that are well cared for allow us to produce better science and more reliable data. We have a company-wide animal welfare policy that defines and drives the standards for our animal care and welfare throughout Envigo.

    Tina<br>Koban, Associate Director of Behavioral Sciences

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    Associate Director of Behavioral Sciences

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    Helmut<br>Ehall, DVM, PhD, Senior Vice President, Veterinary Sciences

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    Ehall, DVM, PhD

    Senior Vice President, Veterinary Sciences

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