Availability: Cryopreserved as a mix of Heterozygous & WT embryos
This model contains a monoallelic deletion of the phosphatase and tensin homolog gene (Pten). Pten mutations have been linked with autism, making this model useful for the study of autism spectrum disorders.
The Pten Knockout Rat model was originally created at SAGE Labs, Inc. in St. Louis, MO and distributed out of the Boyertown, PA facility. The line continues to be maintained through the original SAGE Labs animal inventory acquired by Envigo.