CLOSE ×

    Cardiovascular

    Brooks SD, Hileman SM, Chantler PD, Milde SA, Lemaster KA, Frisbee SJ, Shoemaker JK, Jackson DN, Frisbee JC., Protection from vascular dysfunction in female rats with chronic stress and depressive symptoms, Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H1070-H1084. doi: 10.1152/ajpheart.00647.2017. Epub 2018 Feb 16.

    Diabetes type 2

    Agrawal, R., Zhuang, Y., Cummings, B. P., Stanhope, K. L., Graham, J. L., Havel, P. J., & Gomez-Pinilla, F. (2014)., Deterioration of plasticity and metabolic homeostasis in the brain of the UCD-T2DM rat model of naturally occurring type-2 diabetes., Biochimica Et Biophysica Acta, 1842(9), 1313-1323. doi:10.1016/j.bbadis.2014.05.007 [doi]

    General studies

    Mittwede, P. N., Xiang, L., Lu, S., Clemmer, J. S., & Hester, R. L. (2013)., A novel experimental model of orthopedic trauma with acute kidney injury in obese zucker rats., Physiological Reports, 1(5), e00097. doi:10.1002/phy2.97 [doi]
    do Carmo, J. M., da Silva, A. A., Rushing, J. S., & Hall, J. E. (2012)., Activation of the central melanocortin system contributes to the increased arterial pressure in obese zucker rats., American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 302(5), R561-7. doi:10.1152/ajpregu.00392.2011 [doi]
    Carrier, B., Wen, S., Zigouras, S., Browne, R. W., Li, Z., Patel, M. S., . . . Rideout, T. C. (2014)., Alpha-lipoic acid reduces LDL-particle number and PCSK9 concentrations in high-fat fed obese zucker rats., PloS One, 9(3), e90863. doi:10.1371/journal.pone.0090863 [doi]
    Li, Z., Dungan, C. M., Carrier, B., Rideout, T. C., & Williamson, D. L. (2014)., Alpha-lipoic acid supplementation reduces mTORC1 signaling in skeletal muscle from high fat fed, obese zucker rats., Lipids, 49(12), 1193-1201. doi:10.1007/s11745-014-3964-x [doi]
    Lin, D. C., Zhang, J., Zhuang, R., Li, F., Nguyen, K., Chen, M., . . . Luo, J. (2011)., AMG 837: A novel GPR40/FFA1 agonist that enhances insulin secretion and lowers glucose levels in rodents., PloS One, 6(11), e27270. doi:10.1371/journal.pone.0027270 [doi]
    Habegger, K. M., Hoffman, N. J., Ridenour, C. M., Brozinick, J. T., & Elmendorf, J. S. (2012)., AMPK enhances insulin-stimulated GLUT4 regulation via lowering membrane cholesterol., Endocrinology, 153(5), 2130-2141. doi:10.1210/en.2011-2099 [doi]
    Prasannarong, M., Santos, F. R., & Henriksen, E. J. (2012)., ANG-(1-7) reduces ANG II-induced insulin resistance by enhancing akt phosphorylation via a mas receptor-dependent mechanism in rat skeletal muscle., Biochemical and Biophysical Research Communications, 426(3), 369-373. doi:10.1016/j.bbrc.2012.08.093 [doi]
    Slyvka, Y., Wang, Z., Yee, J., Inman, S. R., & Nowak, F. V. (2011)., Antioxidant diet, gender and age affect renal expression of nitric oxide synthases in obese diabetic rats., Nitric Oxide : Biology and Chemistry / Official Journal of the Nitric Oxide Society, 24(1), 50-60. doi:10.1016/j.niox.2010.11.004 [doi]
    Johnson, F. K., Peyton, K. J., Liu, X. M., Azam, M. A., Shebib, A. R., Johnson, R. A., & Durante, W. (2015)., Arginase promotes endothelial dysfunction and hypertension in obese rats., Obesity (Silver Spring, Md.), 23(2), 383-390. doi:10.1002/oby.20969 [doi]
    Clemmer, J. S., Xiang, L., Lu, S., Mittwede, P. N., & Hester, R. L. (2014)., beta2-adrenergic regulation of stress hyperglycemia following hemorrhage in the obese zucker rat., Physiological Reports, 2(12), 10.14814/phy2.12215. Print 2014 Dec 1. doi:10.14814/phy2.12215 [doi]
    Butcher, J. T., Goodwill, A. G., Stanley, S. C., & Frisbee, J. C. (2013)., Blunted temporal activity of microvascular perfusion heterogeneity in metabolic syndrome: A new attractor for peripheral vascular disease?, American Journal of Physiology.Heart and Circulatory Physiology, 304(4), H547-58. doi:10.1152/ajpheart.00805.2012 [doi]
    Fink, A. M., Topchiy, I., Ragozzino, M., Amodeo, D. A., Waxman, J. A., Radulovacki, M. G., & Carley, D. W. (2014)., Brown norway and zucker lean rats demonstrate circadian variation in ventilation and sleep apnea., Sleep, 37(4), 715-721. doi:10.5665/sleep.3576 [doi]
    Noratto, G. D., Garcia-Mazcorro, J. F., Markel, M., Martino, H. S., Minamoto, Y., Steiner, J. M., . . . Mertens-Talcott, S. U. (2014)., Carbohydrate-free peach (prunus persica) and plum (prunus salicina) [corrected] juice affects fecal microbial ecology in an obese animal model., PloS One, 9(7), e101723. doi:10.1371/journal.pone.0101723 [doi]
    Chantler, P. D., Shrader, C. D., Tabone, L. E., d'Audiffret, A. C., Huseynova, K., Brooks, S. D., . . . Frisbee, J. C. (2015)., Cerebral cortical microvascular rarefaction in metabolic syndrome is dependent on insulin resistance and loss of nitric oxide bioavailability., Microcirculation (New York, N.Y.: 1994), 22(6), 435-445. doi:10.1111/micc.12209 [doi]
    Zhang, Q., Celestino, J., Schmandt, R., McCampbell, A. S., Urbauer, D. L., Meyer, L. A., . . . Lu, K. H. (2013)., Chemopreventive effects of metformin on obesity-associated endometrial proliferation., American Journal of Obstetrics and Gynecology, 209(1), 24.e1-24.e12. doi:10.1016/j.ajog.2013.03.008 [doi]
    Marchionne, E. M., Diamond-Stanic, M. K., Prasonnarong, M., & Henriksen, E. J. (2012)., Chronic renin inhibition with aliskiren improves glucose tolerance, insulin sensitivity, and skeletal muscle glucose transport activity in obese zucker rats., American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 302(1), R137-42. doi:10.1152/ajpregu.00448.2011 [doi]
    Rideout, T. C., Carrier, B., Wen, S., Raslawsky, A., Browne, R. W., & Harding, S. V. (2015)., Complementary cholesterol-lowering response of a Phytosterol/alpha-lipoic acid combination in obese zucker rats., Journal of Dietary Supplements, doi:10.3109/19390211.2015.1008616 [doi]
    DeClercq, V., Taylor, C. G., Wigle, J., Wright, B., Tworek, L., & Zahradka, P. (2012)., Conjugated linoleic acid improves blood pressure by increasing adiponectin and endothelial nitric oxide synthase activity., The Journal of Nutritional Biochemistry, 23(5), 487-493. doi:10.1016/j.jnutbio.2011.02.003 [doi]
    Noratto, G., Martino, H. S., Simbo, S., Byrne, D., & Mertens-Talcott, S. U. (2015)., Consumption of polyphenol-rich peach and plum juice prevents risk factors for obesity-related metabolic disorders and cardiovascular disease in zucker rats., The Journal of Nutritional Biochemistry, 26(6), 633-641. doi:10.1016/j.jnutbio.2014.12.014 [doi]
    Townsend, E. A., Beloate, L. N., Huskinson, S. L., Roma, P. G., & Freeman, K. B. (2015)., Corn oil, but not cocaine, is a more effective reinforcer in obese than in lean zucker rats., Physiology & Behavior, 143, 136-141. doi:10.1016/j.physbeh.2015.03.002 [doi]
    Baranowski, M., Enns, J., Blewett, H., Yakandawala, U., Zahradka, P., & Taylor, C. G. (2012)., Dietary flaxseed oil reduces adipocyte size, adipose monocyte chemoattractant protein-1 levels and T-cell infiltration in obese, insulin-resistant rats., Cytokine, 59(2), 382-391. doi:10.1016/j.cyto.2012.04.004 [doi]
    Hakkak, R., Al-Dwairi, A., Fuchs, G. J., Korourian, S., & Simmen, F. A. (2012)., Dietary soy protein induces hepatic lipogenic enzyme gene expression while suppressing hepatosteatosis in obese female zucker rats bearing DMBA-initiated mammary tumors., Genes & Nutrition, 7(4), 549-558. doi:10.1007/s12263-012-0294-6 [doi]
    Butcher, J. T., Goodwill, A. G., Stanley, S. C., & Frisbee, J. C. (2013)., Differential impact of dilator stimuli on increased myogenic activation of cerebral and skeletal muscle resistance arterioles in obese zucker rats., Microcirculation (New York, N.Y.: 1994), 20(7), 579-589. doi:10.1111/micc.12056 [doi]
    Diaz-Villasenor, A., Granados, O., Gonzalez-Palacios, B., Tovar-Palacio, C., Torre-Villalvazo, I., Olivares-Garcia, V., . . . Tovar, A. R. (2013)., Differential modulation of the functionality of white adipose tissue of obese zucker (fa/fa) rats by the type of protein and the amount and type of fat., The Journal of Nutritional Biochemistry, 24(11), 1798-1809. doi:10.1016/j.jnutbio.2013.03.007 [doi]
    Frisbee, J. C., Goodwill, A. G., Frisbee, S. J., Butcher, J. T., Brock, R. W., Olfert, I. M., . . . Chantler, P. D. (2014)., Distinct temporal phases of microvascular rarefaction in skeletal muscle of obese zucker rats., American Journal of Physiology.Heart and Circulatory Physiology, 307(12), H1714-28. doi:10.1152/ajpheart.00605.2014 [doi]
    Peterson, J. M., Mart, R., & Bond, C. E. (2014)., Effect of obesity and exercise on the expression of the novel myokines, myonectin and fibronectin type III domain containing 5., Peerj, 2, e605. doi:10.7717/peerj.605 [doi]
    Bhutta, H. Y., Rajpal, N., White, W., Freudenberg, J. M., Liu, Y., Way, J., . . . Chen, L. (2015)., Effect of roux-en-Y gastric bypass surgery on bile acid metabolism in normal and obese diabetic rats., PloS One, 10(3), e0122273. doi:10.1371/journal.pone.0122273 [doi]
    Casey, J. M., Banz, W. J., Krul, E. S., Butteiger, D. N., Goldstein, D. A., & Davis, J. E. (2013)., Effect of stearidonic acid-enriched soybean oil on fatty acid profile and metabolic parameters in lean and obese zucker rats., Lipids in Health and Disease, 12, 147-511X-12-147. doi:10.1186/1476-511X-12-147 [doi]
    Disanzo, B. L., & You, T. (2014)., Effects of exercise training on indicators of adipose tissue angiogenesis and hypoxia in obese rats., Metabolism: Clinical and Experimental, 63(4), 452-455. doi:10.1016/j.metabol.2013.12.004 [doi]
    Bruijnzeel, A. W., Corrie, L. W., Rogers, J. A., & Yamada, H. (2011)., Effects of insulin and leptin in the ventral tegmental area and arcuate hypothalamic nucleus on food intake and brain reward function in female rats., Behavioural Brain Research, 219(2), 254-264. doi:10.1016/j.bbr.2011.01.020 [doi]
    Murthy, S. N., Pankey, E. A., Banka, A. A., Badejo, A. M.,Jr, Wekerle, R., Vilija, V., . . . Fonseca, V. A. (2012)., Effects of insulin detemir on balloon catheter injured carotid artery in zucker fatty rats., Journal of Diabetes and its Complications, 26(6), 470-475. doi:10.1016/j.jdiacomp.2012.05.019 [doi]
    Feresin, R. G., Johnson, S. A., Elam, M. L., Jo, E., Arjmandi, B. H., & Hakkak, R. (2014)., Effects of obesity on bone mass and quality in ovariectomized female zucker rats., Journal of Obesity, 2014, 690123. doi:10.1155/2014/690123 [doi]
    Wickramasekara, S. I., Zandkarimi, F., Morre, J., Kirkwood, J., Legette, L., Jiang, Y., . . . Maier, C. S. (2013), Electrospray quadrupole travelling wave ion mobility time-of-flight mass spectrometry for the detection of plasma metabolome changes caused by xanthohumol in obese zucker (fa/fa) rats., Metabolites, 3(3), 701-717. doi:10.3390/metabo3030701 [doi]
    Muhammad, A. B., Lokhandwala, M. F., & Banday, A. A. (2011)., Exercise reduces oxidative stress but does not alleviate hyperinsulinemia or renal dopamine D1 receptor dysfunction in obese rats., American Journal of Physiology.Renal Physiology, 300(1), F98-104. doi:10.1152/ajprenal.00386.2010 [doi]
    Blackler, R., Syer, S., Bolla, M., Ongini, E., & Wallace, J. L. (2012)., Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence., PloS One, 7(4), e35196. doi:10.1371/journal.pone.0035196 [doi]
    Palacios-Gonzalez, B., Zarain-Herzberg, A., Flores-Galicia, I., Noriega, L. G., Aleman-Escondrillas, G., Zarinan, T., . . . Tovar, A. R. (2014)., Genistein stimulates fatty acid oxidation in a leptin receptor-independent manner through the JAK2-mediated phosphorylation and activation of AMPK in skeletal muscle., Biochimica Et Biophysica Acta, 1841(1), 132-140. doi:10.1016/j.bbalip.2013.08.018 [doi]
    Samuel, P., Ali, Q., Sabuhi, R., Wu, Y., & Hussain, T. (2012)., High na intake increases renal angiotensin II levels and reduces expression of the ACE2-AT(2)R-MasR axis in obese zucker rats., American Journal of Physiology.Renal Physiology, 303(3), F412-9. doi:10.1152/ajprenal.00097.2012 [doi]
    Gomez-Solis, A., Reyes-Esparza, J., Garcia-Vazquez, F., Alvarez-Ayala, E., & Rodriguez-Fragoso, L. (2014)., Immuno-modulator metallo-peptide reduces inflammatory state in obese zucker fa/fa rats., International Journal of Biomedical Science : IJBS, 10(3), 172-181.
    Xiang, L., Clemmer, J. S., Lu, S., & Mittwede, P. N. (2013)., Impaired blood pressure compensation following hemorrhage in conscious obese zucker rats., Life Sciences, 93(5-6), 214-219. doi:10.1016/j.lfs.2013.06.006 [doi]
    Xiang, L., Lu, S., Fuller, W., Aneja, A., Russell, G. V., Jones, L. B., & Hester, R. (2012)., Impaired blood pressure recovery to hemorrhage in obese zucker rats with orthopedic trauma. American Journal of Physiology., Heart and Circulatory Physiology, 302(1), H340-8. doi:10.1152/ajpheart.00439.2011 [doi]
    Boomhower, S. R., Rasmussen, E. B., & Doherty, T. S. (2013), Impulsive-choice patterns for food in genetically lean and obese zucker rats., Behavioural Brain Research, 241, 214-221. doi:10.1016/j.bbr.2012.12.013 [doi]
    Zhang, Y., Chen, W., Li, R., Li, Y., Ge, Y., & Chen, G. (2011)., Insulin-regulated srebp-1c and Pck1 mRNA expression in primary hepatocytes from zucker fatty but not lean rats is affected by feeding conditions., PloS One, 6(6), e21342. doi:10.1371/journal.pone.0021342 [doi]
    Ciriello, J., & Moreau, J. M. (2012)., Leptin signaling in the nucleus of the solitary tract alters the cardiovascular responses to activation of the chemoreceptor reflex., American Journal of Physiology.Regulatory, Integrative and Comparative Physiology, 303(7), R727-36. doi:10.1152/ajpregu.00068.2012 [doi]
    Blanc, V., & Davidson, N. O. (2011)., Mouse and other rodent models of C to U RNA editing., Methods in Molecular Biology (Clifton, N.J.), 718, 121-135. doi:10.1007/978-1-61779-018-8_7 [doi]
    Rasmussen, E. B., & Hillman, C. (2011)., Naloxone and rimonabant reduce the reinforcing properties of exercise in rats., Experimental and Clinical Psychopharmacology, 19(6), 389-400. doi:10.1037/a0024142 [doi]
    Buckley, J. L., & Rasmussen, E. B. (2012)., Obese and lean zucker rats demonstrate differential sensitivity to rates of food reinforcement in a choice procedure., Physiology & Behavior, 108, 19-27. doi:10.1016/j.physbeh.2012.10.001 [doi]
    Washington, M. C., Park, K. H., & Sayegh, A. I. (2014)., Obese and lean zucker rats respond similarly to intraperitoneal administration of gastrin-releasing peptides., Peptides, 58, 36-41. doi:10.1016/j.peptides.2014.04.020 [doi]
    Thanos, P. K., Robison, L. S., Robinson, J. K., Michaelides, M., Wang, G. J., & Volkow, N. D. (2013)., Obese rats with deficient leptin signaling exhibit heightened sensitivity to olfactory food cues., Synapse (New York, N.Y.), 67(4), 171-178. doi:10.1002/syn.21627 [doi]
    Uthus, E. O., & Picklo MJ, S. (2011)., Obesity reduces methionine sulphoxide reductase activity in visceral adipose tissue., Free Radical Research, 45(9), 1052-1060. doi:10.3109/10715762.2011.591793 [doi]
    Gupta, D., Leahy, A. A., Monga, N., Peshavaria, M., Jetton, T. L., & Leahy, J. L. (2013)., Peroxisome proliferator-activated receptor gamma (PPARgamma) and its target genes are downstream effectors of FoxO1 protein in islet beta-cells: Mechanism of beta-cell compensation and failure., The Journal of Biological Chemistry, 288(35), 25440-25449. doi:10.1074/jbc.M113.486852 [doi]
    Reyes-Esparza, J., Mendoza-Rivera, B., De la Cruz-Cordero, R., Duarte-Vazquez, M. A., Rosado, J. L., & Rodriguez-Fragoso, L. (2014)., Pharmacokinetic and pharmacological effects of beta-hydroxyphosphocarnitine in animal models., Pharmacology, 94(1-2), 90-98. doi:10.1159/000366205 [doi]
    Reyes-Esparza, J., Mendoza-Rivera, B., De la Cruz-Cordero, R., Rosado, J. L., Duarte-Vazquez, M. A., Solis, M. G., . . . Rodriguez-Fragoso, L. (2013)., Pharmacological evaluation of a beta-hydroxyphosphonate analogue of l-carnitine in obese zucker fa/fa rats., Basic & Clinical Pharmacology & Toxicology, 112(4), 222-228. doi:10.1111/bcpt.12019 [doi]
    Schade, K. N., Baranwal, A., Liang, C., Mirbolooki, M. R., & Mukherjee, J. (2015)., Preliminary evaluation of beta3-adrenoceptor agonist-induced 18F-FDG metabolic activity of brown adipose tissue in obese zucker rat., Nuclear Medicine and Biology, 42(8), 691-694. doi:10.1016/j.nucmedbio.2015.04.003 [doi]
    Tovar-Palacio, C., Tovar, A. R., Torres, N., Cruz, C., Hernandez-Pando, R., Salas-Garrido, G., . . . Correa-Rotter, R. (2011)., Proinflammatory gene expression and renal lipogenesis are modulated by dietary protein content in obese zucker fa/fa rats., American Journal of Physiology.Renal Physiology, 300(1), F263-71. doi:10.1152/ajprenal.00171.2010 [doi]
    Lobato, N. S., Filgueira, F. P., Prakash, R., Giachini, F. R., Ergul, A., Carvalho, M. H., . . . Fortes, Z. B. (2013)., Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese zucker rats., PloS One, 8(5), e63449. doi:10.1371/journal.pone.0063449 [doi]
    Jiao, J., Bae, E. J., Bandyopadhyay, G., Oliver, J., Marathe, C., Chen, M., . . . Saberi, M. (2013), Restoration of euglycemia after duodenal bypass surgery is reliant on central and peripheral inputs in zucker fa/fa rats., Diabetes, 62(4), 1074-1083. doi:10.2337/db12-0681 [doi]
    Rasmussen, E. B., Reilly, W., Buckley, J., & Boomhower, S. R. (2012)., Rimonabant reduces the essential value of food in the genetically obese zucker rat: An exponential demand analysis., Physiology & Behavior, 105(3), 734-741. doi:10.1016/j.physbeh.2011.10.009 [doi]
    Buckley, J. L., & Rasmussen, E. B. (2014)., Rimonabant's reductive effects on high densities of food reinforcement, but not palatability, in lean and obese zucker rats., Psychopharmacology, 231(10), 2159-2170. doi:10.1007/s00213-013-3366-4 [doi]
    Hakkak, R., Zeng, H., Dhakal, I. B., & Korourian, S. (2015)., Short- and long-term soy diet versus casein protects liver steatosis independent of the arginine content., Journal of Medicinal Food, doi:10.1089/jmf.2015.0002 [doi]
    Jin, J., Machado, E. R., Yu, H., Zhang, X., Lu, Z., Li, Y., . . . Huang, Y. (2014)., Simvastatin inhibits LPS-induced alveolar bone loss during metabolic syndrome., Journal of Dental Research, 93(3), 294-299. doi:10.1177/0022034513516980 [doi]
    Davis, D. D., Ruiz, A. L., Yanes, L. L., Iliescu, R., Yuan, K., Moulana, M., . . . Reckelhoff, J. F. (2012)., Testosterone supplementation in male obese zucker rats reduces body weight and improves insulin sensitivity but increases blood pressure., Hypertension, 59(3), 726-731. doi:10.1161/HYPERTENSIONAHA.111.180943 [doi]
    Li, Y., Zhang, Y., Li, R., Chen, W., Howell, M., Zhang, R., & Chen, G. (2012)., The hepatic Raldh1 expression is elevated in zucker fatty rats and its over-expression introduced the retinal-induced srebp-1c expression in INS-1 cells., PloS One, 7(9), e45210. doi:10.1371/journal.pone.0045210 [doi]
    Prasannarong, M., Santos, F. R., Hooshmand, P., Hooshmand, P., Giovannini, F. J., & Henriksen, E. J. (2014)., The lipid peroxidation end-product and oxidant 4-hydroxynonenal induces insulin resistance in rat slow-twitch skeletal muscle., Archives of Physiology and Biochemistry, 120(1), 22-28. doi:10.3109/13813455.2013.834937 [doi]
    Ochman, A. R., Lipinski, C. A., Handler, J. A., Reaume, A. G., & Saporito, M. S. (2012)., The lyn kinase activator MLR-1023 is a novel insulin receptor potentiator that elicits a rapid-onset and durable improvement in glucose homeostasis in animal models of type 2 diabetes., The Journal of Pharmacology and Experimental Therapeutics, 342(1), 23-32. doi:10.1124/jpet.112.192187 [doi]
    Zhan, Y., Shi, H., Caligiuri, S. P., Wu, Y., Declercq, V., Taylor, C. G., . . . Aukema, H. M. (2015)., Trans-10,cis-12-conjugated linoleic acid worsens renal pathology and alters cyclooxygenase derived oxylipins in obesity-associated nephropathy., The Journal of Nutritional Biochemistry, 26(2), 130-137. doi:10.1016/j.jnutbio.2014.09.011 [doi]
    Chen, W., Howell, M. L., Li, Y., Li, R., & Chen, G. (2014), Vitamin A and feeding statuses modulate the insulin-regulated gene expression in zucker lean and fatty primary rat hepatocytes., PloS One, 9(8), e100868. doi:10.1371/journal.pone.0100868 [doi]
    Legette, L. L., Luna, A. Y., Reed, R. L., Miranda, C. L., Bobe, G., Proteau, R. R., & Stevens, J. F. (2013)., Xanthohumol lowers body weight and fasting plasma glucose in obese male zucker fa/fa rats., Phytochemistry, 91, 236-241. doi:10.1016/j.phytochem.2012.04.018 [doi]

    Obesity

    Ali, Q., Patel, S., & Hussain, T. (2015)., Angiotensin AT2 receptor agonist prevents salt-sensitive hypertension in obese zucker rats., American Journal of Physiology.Renal Physiology, 308(12), F1379-85. doi:10.1152/ajprenal.00002.2015 [doi]
    Ali, Q., Wu, Y., & Hussain, T. (2013)., Chronic AT2 receptor activation increases renal ACE2 activity, attenuates AT1 receptor function and blood pressure in obese zucker rats., Kidney International, 84(5), 931-939. doi:10.1038/ki.2013.193 [doi]

    Surgical

    Brooks SD, Hileman SM, Chantler PD, Milde SA, Lemaster KA, Frisbee SJ, Shoemaker JK, Jackson DN, Frisbee JC., Protection from vascular dysfunction in female rats with chronic stress and depressive symptoms, Am J Physiol Heart Circ Physiol. 2018 May 1;314(5):H1070-H1084. doi: 10.1152/ajpheart.00647.2017. Epub 2018 Feb 16.