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General studies

Li, Fu; Ulrich, Michelle L; Shih, Vincent Feng-Sheng; Cochran, Julia H; Hunter, Joshua H; Westendorf, Lori; Neale, Jason; Benjamin, Dennis R;, Mouse Strains Influence Clearance and Efficacy of Antibody and Antibody-Drug Conjugate Via Fc-Fc?R Interaction, Molecular cancer therapeutics Vol.18, 2019

Imaging

Gill H, Seipert R, Carroll VM, Gouasmat A, Yin J, Ogasawara A, de Jong I, Phan MM, Wang X, Yang J, Ilovich O, Marik J, Williams SP, The Production, Quality Control, and Characterization of ZED8, a CD8-Specific, AAPS J. 2020 Jan 3;22(2):22.

Immunology

Liu, Z., Gunasekaran, K., Wang, W., Razinkov, V., Sekirov, L., Leng, E., . . . Yan, W. (2014)., Asymmetrical fc engineering greatly enhances antibody-dependent cellular cytotoxicity (ADCC) effector function and stability of the modified antibodies., The Journal of Biological Chemistry, 289(6), 3571-3590. doi:10.1074/jbc.M113.513366 [doi]
Fang, R., Ismail, N., & Walker, D. H. (2012)., Contribution of NK cells to the innate phase of host protection against an intracellular bacterium targeting systemic endothelium., The American Journal of Pathology, 181(1), 185-195. doi:10.1016/j.ajpath.2012.03.020 [doi]
Wallach-Dayan, S. B., Elkayam, L., Golan-Gerstl, R., Konikov, J., Zisman, P., Dayan, M. R., . . . Breuer, R. (2015), Cutting edge: FasL(+) immune cells promote resolution of fibrosis., Journal of Autoimmunity, 59, 67-76. doi:10.1016/j.jaut.2015.02.006 [doi]
Rogovskyy, A. S., Casselli, T., Tourand, Y., Jones, C. R., Owen, J. P., Mason, K. L., . . . Bankhead, T. (2015)., Evaluation of the importance of VlsE antigenic variation for the enzootic cycle of borrelia burgdorferi., PloS One, 10(4), e0124268. doi:10.1371/journal.pone.0124268 [doi]
Hossain, M., Qadri, S. M., & Liu, L. (2012)., Inhibition of nitric oxide synthesis enhances leukocyte rolling and adhesion in human microvasculature, Journal of Inflammation (London, England), 9(1), 28-9255-9-28. doi:10.1186/1476-9255-9-28 [doi]
Jones, R. J., Iempridee, T., Wang, X., Lee, H. C., Mertz, J. E., Kenney, S. C., . . . Orlowski, R. Z. (2016)., Lenalidomide, thalidomide, and pomalidomide reactivate the epstein-barr virus lytic cycle through phosphoinositide 3-kinase signaling and ikaros expression., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(19), 4901-4912. doi:1078-0432.CCR-15-2242 [pii]
Burette M, Allombert J, Lambou K, Maarifi G, Nisole S, Di Russo Case E, Blanchet FP, Hassen-Khodja C, Cabantous S, Samuel J, Martinez E, Bonazzi M., Modulation of innate immune signaling by a Coxiella burnetii eukaryotic-like effector protein, Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13708-13718. doi: 10.1073/pnas.1914892117. Epub 2020 Jun 1.
Gill, S., Vasey, A. E., De Souza, A., Baker, J., Smith, A. T., Kohrt, H. E., . . . Negrin, R. S. (2012)., Rapid development of exhaustion and down-regulation of eomesodermin limit the antitumor activity of adoptively transferred murine natural killer cells, Blood, 119(24), 5758-5768. doi:10.1182/blood-2012-03-415364 [doi]
Wintrob, Z. A., Oppong, E. K., Foster, M., Martorana, M., Tse, Y. C., Zhong, L., . . . Ceacareanu, A. C. (2014), Sexual dimorphism, weight gain and glucose intolerance in a B- and T-cell deficient mouse model., Cytokine, 67(2), 102-106. doi:10.1016/j.cyto.2014.02.011 [doi]
Manthey, Carl L; Moore, Beverley A; Chen, Yanqing; Loza, Matthew J; Yao, Xiang; Liu, Hao; Belkowski, Stanley M; Raymond-Parks, Holly; Dunford, Paul J; Leon, Francisco; Towne, Jennifer E; Plevy, Scott E;, The CSF-1-receptor inhibitor, JNJ-40346527 (PRV-6527), reduced inflammatory macrophage recruitment to the intestinal mucosa and suppressed murine T cell mediated colitis., PloS one Vol.14, 2019
Rosario, M., Liu, B., Kong, L., Collins, L. I., Schneider, S. E., Chen, X., . . . Fehniger, T. A. (2016)., The IL-15-based ALT-803 complex enhances FcgammaRIIIa-triggered NK cell responses and in vivo clearance of B cell lymphomas., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(3), 596-608. doi:10.1158/1078-0432.CCR-15-1419 [doi]
Felder, Mildred; Kapur, Arvinder; Rakhmilevich, Alexander L; Qu, Xiaoyi; Sondel, Paul M; Gillies, Stephen D; Connor, Joseph; Patankar, Manish S, UC16 suppresses human and murine innate immune responses., Gynecologic oncology Vol.152, 2019

Oncology

Jeffrey, S. C., Burke, P. J., Lyon, R. P., Meyer, D. W., Sussman, D., Anderson, M., . . . Senter, P. D. (2013)., A potent anti-CD70 antibody-drug conjugate combining a dimeric pyrrolobenzodiazepine drug with site-specific conjugation technology., Bioconjugate Chemistry, 24(7), 1256-1263. doi:10.1021/bc400217g [doi]
Thomas A, Samykutty A, Gomez-Gutierrez JG, Yin W, Egger ME, McNally M, Chuong P, MacCuaig WM, Albeituni S, Zeiderman M, Li M, Edil BH, Grizzle WE, McMasters KM, McNally LR., Actively Targeted Nanodelivery of Echinomycin Induces Autophagy-Mediated Death in Chemoresistant Pancreatic Cancer In Vivo, Cancers (Basel). 2020 Aug 14;12(8):2279. doi: 10.3390/cancers12082279.
Mahasreshti, P. J., Navarro, J. G., Kataram, M., Wang, M. H., Carey, D., Siegal, G. P., . . . Curiel, D. T. (2001), Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 7(7), 2057-2066.
Sutherland, M. K., Yu, C., Lewis, T. S., Miyamoto, J. B., Morris-Tilden, C. A., Jonas, M., . . . Law, C. L. (2009)., Anti-leukemic activity of lintuzumab (SGN-33) in preclinical models of acute myeloid leukemia., Mabs, 1(5), 481-490. doi:9288 [pii]
Abuqayyas, L., & Balthasar, J. P. (2012)., Application of PBPK modeling to predict monoclonal antibody disposition in plasma and tissues in mouse models of human colorectal cancer., Journal of Pharmacokinetics and Pharmacodynamics, 39(6), 683-710. doi:10.1007/s10928-012-9279-8 [doi]
Do, T. V., Hirst, J., Hyter, S., Roby, K. F., & Godwin, A. K. (2017)., Aurora A kinase regulates non-homologous end-joining and poly(ADP-ribose) polymerase function in ovarian carcinoma cells., Oncotarget, 8(31), 50376-50392. doi:10.18632/oncotarget.18970 [doi]
Zhang, L., Nomie, K., Zhang, H., Bell, T., Pham, L., Kadri, S., . . . Wang, M. (2017), B-cell lymphoma patient-derived xenograft models enable drug discovery and are a platform for personalized therapy., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 23(15), 4212-4223. doi:10.1158/1078-0432.CCR-16-2703 [doi]
Zhang, C. C., Pavlicek, A., Zhang, Q., Lira, M. E., Painter, C. L., Yan, Z., . . . Christensen, J. G. (2012)., Biomarker and pharmacologic evaluation of the gamma-secretase inhibitor PF-03084014 in breast cancer models., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(18), 5008-5019. doi:10.1158/1078-0432.CCR-12-1379 [doi]
Francisco, J. A., Cerveny, C. G., Meyer, D. L., Mixan, B. J., Klussman, K., Chace, D. F., . . . Wahl, A. F. (2003)., cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity., Blood, 102(4), 1458-1465. doi:10.1182/blood-2003-01-0039 [doi]
Bhatta, Puspanjali; Dhukhwa, Asmita; Sheehan, Kelly; Al Aameri, Raheem F H; Borse, Vikrant; Ghosh, Sumana; Sheth, Sandeep; Mamillapalli, Chaitanya; Rybak, Leonard; Ramkumar, Vickram; Mukherjea, Debashree;, Capsaicin Protects Against Cisplatin Ototoxicity by Changing the STAT3/STAT1 Ratio and Activating Cannabinoid (CB2) Receptors in the Cochlea., Scientific reports Vol.9, 2019
McKnight BN, Kim S, Boerner JL, Viola NT., Cetuximab PET delineated changes in cellular distribution of EGFR upon dasatinib treatment in triple negative breast cancer, Breast Cancer Res. 2020 Apr 15;22(1):37. doi: 10.1186/s13058-020-01270-1.
Kryeziu, K., Pirker, C., Englinger, B., van Schoonhoven, S., Spitzwieser, M., Mohr, T., . . . Heffeter, P. (2016), Chronic arsenic trioxide exposure leads to enhanced aggressiveness via met oncogene addiction in cancer cells, Oncotarget, 7(19), 27379-27393. doi:10.18632/oncotarget.8415 [doi]
Cocco, E., Shapiro, E. M., Gasparrini, S., Lopez, S., Schwab, C. L., Bellone, S., . . . Santin, A. D. (2015)., Clostridium perfringens enterotoxin C-terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy-resistant ovarian cancer, International Journal of Cancer, 137(11), 2618-2629. doi:10.1002/ijc.29632 [doi]
Balkin, E. R., Liu, D., Jia, F., Ruthengael, V. C., Shaffer, S. M., Miller, W. H., & Lewis, M. R. (2014)., Comparative biodistributions and dosimetry of [(1)(7)(7)lu]DOTA-anti-bcl-2-PNA-tyr(3)-octreotate and [(1)(7)(7)lu]DOTA-tyr(3)-octreotate in a mouse model of B-cell lymphoma/leukemia., Nuclear Medicine and Biology, 41(1), 36-42. doi:10.1016/j.nucmedbio.2013.10.006 [doi]
Glaser, G., Weroha, S. J., Becker, M. A., Hou, X., Enderica-Gonzalez, S., Harrington, S. C., & Haluska, P. (2015)., Conventional chemotherapy and oncogenic pathway targeting in ovarian carcinosarcoma using a patient-derived tumorgraft, PloS One, 10(5), e0126867. doi:10.1371/journal.pone.0126867 [doi]
Jia, F., Balaji, B. S., Gallazzi, F., & Lewis, M. R. (2015)., Copper-64-labeled anti-bcl-2 PNA-peptide conjugates selectively localize to bcl-2-positive tumors in mouse models of B-cell lymphoma., Nuclear Medicine and Biology, doi:S0969-8051(15)00094-3 [pii]
Aregueta-Robles, U., Fajardo-Ramirez, O. R., Villela, L., Gutierrez-Uribe, J. A., Hernandez-Hernandez, J., Lopez-Sanchez, R. D. C., . . . Serna-Saldivar, S. (2018)., Cytotoxic activity of a black bean (phaseolus vulgaris L.) extract and its flavonoid fraction in both in vitro and in vivo models of lymphoma., Revista De Investigacion Clinica; Organo Del Hospital De Enfermedades De La Nutricion, 70(1), 32-39. doi:10.24875/RIC.17002395 [doi]
Hamblett, K. J., Senter, P. D., Chace, D. F., Sun, M. M., Lenox, J., Cerveny, C. G., . . . Francisco, J. A. (2004)., Effects of drug loading on the antitumor activity of a monoclonal antibody drug conjugate., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 10(20), 7063-7070. doi:10/20/7063 [pii]
Romani, C., Cocco, E., Bignotti, E., Moratto, D., Bugatti, A., Todeschini, P., . . . Mitola, S. (2015), Evaluation of a novel human IgG1 anti-claudin3 antibody that specifically recognizes its aberrantly localized antigen in ovarian cancer cells and that is suitable for selective drug delivery, Oncotarget, 6(33), 34617-34628. doi:10.18632/oncotarget.5315 [doi]
Dingli, D., Diaz, R. M., Bergert, E. R., O'Connor, M. K., Morris, J. C., & Russell, S. J. (2003)., Genetically targeted radiotherapy for multiple myeloma, Blood, 102(2), 489-496. doi:10.1182/blood-2002-11-3390 [doi]
Han, Chanhee; Perrone, Emanuele; Zeybek, Burak; Bellone, Stefania; Tymon-Rosario, Joan; Altwerger, Gary; Menderes, Gulden; Feinberg, Jacqueline; Haines, Kaitlin; Muller Karger, Mariana Espinal; Bianchi, Anna; Zammataro, Luca; Manzano, Aranzazu; Bonazzoli, Elena; Manara, Paola; Buza, Natalia; Hui, Pei; Ratner, Elena; Silasi, Dan-Arin; Huang, Gloria S; Azodi, Masoud; Schwartz, Peter E; Lopez, Salvatore; Santin, Alessandro D, In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinoma., Gynecologic oncology Vol.10, 2019
Zhang, L., Pham, L. V., Newberry, K. J., Ou, Z., Liang, R., Qian, J., . . . Wang, M. (2013)., In vitro and in vivo therapeutic efficacy of carfilzomib in mantle cell lymphoma: Targeting the immunoproteasome., Molecular Cancer Therapeutics, 12(11), 2494-2504. doi:10.1158/1535-7163.MCT-13-0156 [doi]
Han C, Perrone E, Zeybek B, Bellone S, Tymon-Rosario J, Altwerger G, Menderes G, Feinberg J, Haines K, Muller Karger ME, Bianchi A, Zammataro L, Manzano A, Bonazzoli E, Manara P, Buza N, Hui P, Ratner E, Silasi DA, Huang GS, Azodi M, Schwartz PE, Lopez S, Santin AD., In vitro and in vivo activity of sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2 (Trop-2) in uterine serous carcinoma, Gynecol Oncol. 2020 Feb;156(2):430-438. doi: 10.1016/j.ygyno.2019.11.018. Epub 2019 Dec 12.
Lu, A., Pallero, M. A., Lei, W., Hong, H., Yang, Y., Suto, M. J., & Murphy-Ullrich, J. E. (2016), Inhibition of transforming growth factor-beta activation diminishes tumor progression and osteolytic bone disease in mouse models of multiple myeloma., The American Journal of Pathology, 186(3), 678-690. doi:10.1016/j.ajpath.2015.11.003 [doi]
Jones RJ, Singh RK, Shirazi F, Wan J, Wang H, Wang X, Ha MJ, Baljevic M, Kuiatse I, Davis RE, Orlowski RZ., Intravenous Immunoglobulin G Suppresses Heat Shock Protein (HSP)-70 Expression and Enhances the Activity of HSP90 and Proteasome Inhibitors, Front Immunol. 2020 Aug 13;11:1816. doi: 10.3389/fimmu.2020.01816. eCollection 2020.
Gross, A. C., Cam, H., Phelps, D. A., Saraf, A. J., Bid, H. K., Cam, M., . . . Roberts, R. D. (2018), L-6 and CXCL8 mediate osteosarcoma-lung interactions critical to metastasis., JCI Insight, 3(16), 10.1172/jci.insight.99791. doi:10.1172/jci.insight.99791 [doi]
Junttila, T. T., Akita, R. W., Parsons, K., Fields, C., Lewis Phillips, G. D., Friedman, L. S., . . . Sliwkowski, M. X. (2009)., Ligand-independent HER2/HER3/PI3K complex is disrupted by trastuzumab and is effectively inhibited by the PI3K inhibitor GDC-0941., Cancer Cell, 15(5), 429-440. doi:10.1016/j.ccr.2009.03.020 [doi]
Ashley, J. D., Stefanick, J. F., Schroeder, V. A., Suckow, M. A., Alves, N. J., Suzuki, R., . . . Bilgicer, B. (2014)., Liposomal carfilzomib nanoparticles effectively target multiple myeloma cells and demonstrate enhanced efficacy in vivo, Journal of Controlled Release : Official Journal of the Controlled Release Society, 196, 113-121. doi:10.1016/j.jconrel.2014.10.005 [doi]
Taylor, C. A., Liu, Z., Tang, T. C., Zheng, Q., Francis, S., Wang, T. W., . . . Thompson, J. E. (2012)., Modulation of eIF5A expression using SNS01 nanoparticles inhibits NF-kappaB activity and tumor growth in murine models of multiple myeloma, Molecular Therapy : The Journal of the American Society of Gene Therapy, 20(7), 1305-1314. doi:10.1038/mt.2012.94 [doi]
Pepin, K. M., Chen, J., Glaser, K. J., Mariappan, Y. K., Reuland, B., Ziesmer, S., . . . McGee, K. P. (2014)., MR elastography derived shear stiffness--a new imaging biomarker for the assessment of early tumor response to chemotherapy., Magnetic Resonance in Medicine, 71(5), 1834-1840. doi:10.1002/mrm.24825 [doi]
Smith, R. C., Cramer, M. S., Mitchell, P. J., Capen, A., Huber, L., Wang, R., . . . Heuer, J. G. (2015)., Myostatin neutralization results in preservation of muscle mass and strength in preclinical models of tumor-induced muscle wasting., Molecular Cancer Therapeutics, 14(7), 1661-1670. doi:10.1158/1535-7163.MCT-14-0681 [doi]
Moquist PN, Bovee TD, Waight AB, Mitchell JA, Miyamoto JB, Mason ML, Emmerton KK, Stevens N, Balasubramanian C, Simmons JK, Lyon RP, Senter PD, Doronina SO., Novel Auristatins with High Bystander and Cytotoxic Activities in Drug-Efflux Positive Tumor Models, Mol Cancer Ther. 2020 Dec 7:molcanther.0618.2020. doi: 10.1158/1535-7163.MCT-20-0618. Online ahead of print.
Somwar R, Hofmann NE, Smith B, Odintsov I, Vojnic M, Linkov I, Tam A, Khodos I, Mattar MS, de Stanchina E, Flynn D, Ladanyi M, Drilon A, Shinde U, Davare MA., NTRK kinase domain mutations in cancer variably impact sensitivity to type I and type II inhibitors, Commun Biol. 2020 Dec 16;3(1):776. doi: 10.1038/s42003-020-01508-w.
Jin UH, Michelhaugh SK, Polin LA, Shrestha R, Mittal S, Safe S., Omeprazole Inhibits Glioblastoma Cell Invasion and Tumor Growth, Cancers (Basel). 2020 Jul 28;12(8):2097. doi: 10.3390/cancers12082097.
Chu, K. S., Hasan, W., Rawal, S., Walsh, M. D., Enlow, E. M., Luft, J. C., . . . DeSimone, J. M. (2013)., Plasma, tumor and tissue pharmacokinetics of docetaxel delivered via nanoparticles of different sizes and shapes in mice bearing SKOV-3 human ovarian carcinoma xenograft., Nanomedicine : Nanotechnology, Biology, and Medicine, 9(5), 686-693. doi:10.1016/j.nano.2012.11.008 [doi]
Lopez S, Perrone E, Bellone S, Bonazzoli E, Zeybek B, Han C, Tymon-Rosario J, Altwerger G, Menderes G, Bianchi A, Zammataro L, Manzano A, Manara P, Ratner E, Silasi DA, Huang GS, Azodi M, Schwartz PE, Raspagliesi F, Angioli R, Buza N, Hui P, Bond HM, Santin AD., Preclinical activity of sacituzumab govitecan (IMMU-132) in uterine and ovarian carcinosarcomas, Oncotarget. 2020 Feb 4;11(5):560-570. doi: 10.18632/oncotarget.27342. eCollection 2020 Feb 4.
Perrone E, Lopez S, Zeybek B, Bellone S, Bonazzoli E, Pelligra S, Zammataro L, Manzano A, Manara P, Bianchi A, Buza N, Tymon-Rosario J, Altwerger G, Han C, Menderes G, Ratner E, Silasi DA, Azodi M, Hui P, Schwartz PE, Scambia G, Santin AD., Preclinical Activity of Sacituzumab Govitecan, an Antibody-Drug Conjugate Targeting Trophoblast Cell-Surface Antigen 2 (Trop-2) Linked to the Active Metabolite of Irinotecan (SN-38), in Ovarian Cancer, Front Oncol. 2020 Feb 12;10:118. doi: 10.3389/fonc.2020.00118. eCollection 2020.
McEarchern, J. A., Smith, L. M., McDonagh, C. F., Klussman, K., Gordon, K. A., Morris-Tilden, C. A., . . . Law, C. L. (2008)., Preclinical characterization of SGN-70, a humanized antibody directed against CD70., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 14(23), 7763-7772. doi:10.1158/1078-0432.CCR-08-0493 [doi]
Dingli, D., Timm, M., Russell, S. J., Witzig, T. E., & Rajkumar, S. V. (2002)., Promising preclinical activity of 2-methoxyestradiol in multiple myeloma, Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 8(12), 3948-3954.
Ghilu S, Li Q, Fontaine SD, Santi DV, Kurmasheva RT, Zheng S, Houghton PJ., Prospective use of the single-mouse experimental design for the evaluation of PLX038A, Cancer Chemother Pharmacol. 2020 Feb;85(2):251-263. doi: 10.1007/s00280-019-04017-8. Epub 2020 Jan 11.
Zhou W, Yao Y, Scott AJ, Wilder-Romans K, Dresser JJ, Werner CK, Sun H, Pratt D, Sajjakulnukit P, Zhao SG, Davis M, Nelson BS, Halbrook CJ, Zhang L, Gatto F, Umemura Y, Walker AK, Kachman M, Sarkaria JN, Xiong J, Morgan MA, Rehemtualla A, Castro MG, Lowenstein P, Chandrasekaran S, Lawrence TS, Lyssiotis CA, Wahl DR., Purine metabolism regulates DNA repair and therapy resistance in glioblastoma, Nat Commun. 2020 Jul 30;11(1):3811. doi: 10.1038/s41467-020-17512-x.
Kiziltepe, T., Ashley, J. D., Stefanick, J. F., Qi, Y. M., Alves, N. J., Handlogten, M. W., . . . Bilgicer, B. (2012)., Rationally engineered nanoparticles target multiple myeloma cells, overcome cell-adhesion-mediated drug resistance, and show enhanced efficacy in vivo, Blood Cancer Journal, 2(4), e64. doi:10.1038/bcj.2012.10 [doi]
Lyon, R. P., Bovee, T. D., Doronina, S. O., Burke, P. J., Hunter, J. H., Neff-LaFord, H. D., . . . Senter, P. D. (2015)., Reducing hydrophobicity of homogeneous antibody-drug conjugates improves pharmacokinetics and therapeutic index., Nature Biotechnology, 33(7), 733-735. doi:10.1038/nbt.3212 [doi]
Li, Y., Williams, M. E., Cousar, J. B., Pawluczkowycz, A. W., Lindorfer, M. A., & Taylor, R. P. (2007)., Rituximab-CD20 complexes are shaved from Z138 mantle cell lymphoma cells in intravenous and subcutaneous SCID mouse models., Journal of Immunology (Baltimore, Md.: 1950), 179(6), 4263-4271. doi:179/6/4263 [pii]
Cai D, Wang J, Gao B, Li J, Wu F, Zou JX, Xu J, Jiang Y, Zou H, Huang Z, Borowsky AD, Bold RJ, Lara PN, Li JJ, Chen X, Lam KS, To KF, Kung HJ, Fiehn O, Zhao R, Evans RM, Chen HW, ROR? is a targetable master regulator of cholesterol biosynthesis in a cancer subtype., Nat Commun. 2019 Oct 11;10(1):4621.
Morelli, E., Leone, E., Cantafio, M. E., Di Martino, M. T., Amodio, N., Biamonte, L., . . . Tassone, P. (2015)., Selective targeting of IRF4 by synthetic microRNA-125b-5p mimics induces anti-multiple myeloma activity in vitro and in vivo, Leukemia, 29(11), 2173-2183. doi:10.1038/leu.2015.124 [doi]
Lyon, R. P., Setter, J. R., Bovee, T. D., Doronina, S. O., Hunter, J. H., Anderson, M. E., . . . Senter, P. D. (2014)., Self-hydrolyzing maleimides improve the stability and pharmacological properties of antibody-drug conjugates., Nature Biotechnology, 32(10), 1059-1062. doi:10.1038/nbt.2968 [doi]
Kung Sutherland, M. S., Walter, R. B., Jeffrey, S. C., Burke, P. J., Yu, C., Kostner, H., . . . McEarchern, J. A. (2013)., SGN-CD33A: A novel CD33-targeting antibody-drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML., Blood, 122(8), 1455-1463. doi:10.1182/blood-2013-03-491506 [doi]
Di Martino, M. T., Leone, E., Amodio, N., Foresta, U., Lionetti, M., Pitari, M. R., . . . Tassone, P. (2012)., Synthetic miR-34a mimics as a novel therapeutic agent for multiple myeloma: In vitro and in vivo evidence., Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(22), 6260-6270. doi:10.1158/1078-0432.CCR-12-1708 [doi]
Peng, K. W., Ahmann, G. J., Pham, L., Greipp, P. R., Cattaneo, R., & Russell, S. J. (2001)., Systemic therapy of myeloma xenografts by an attenuated measles virus., Blood, 98(7), 2002-2007.
Pfitzer L, Moser C, Gegenfurtner F, Arner A, Foerster F, Atzberger C, Zisis T, Kubisch-Dohmen R, Busse J, Smith R, Timinszky G, Kalinina OV, Müller R, Wagner E, Vollmar AM, Zahler S., Targeting actin inhibits repair of doxorubicin-induced DNA damage: a novel therapeutic approach for combination therapy., Cell Death Dis. 2019 Apr 3;10(4):302.
Tabe, Y., Shi, Y. X., Zeng, Z., Jin, L., Shikami, M., Hatanaka, Y., . . . Konopleva, M. (2013)., TGF-beta-neutralizing antibody 1D11 enhances cytarabine-induced apoptosis in AML cells in the bone marrow microenvironment., PloS One, 8(6), e62785. doi:10.1371/journal.pone.0062785 [doi]
Daniluk, U., Kerros, C., Tao, R. H., Wise, J. F., Ao, X., Berkova, Z., & Samaniego, F. (2012), The peptide derived from the ig-like domain of human herpesvirus 8 K1 protein induces death in hematological cancer cells., Journal of Experimental & Clinical Cancer Research : CR, 31, 69-9966-31-69. doi:10.1186/1756-9966-31-69 [doi]
Ryan, M. C., Palanca-Wessels, M. C., Schimpf, B., Gordon, K. A., Kostner, H., Meyer, B., . . . Benjamin, D. (2017)., Therapeutic potential of SGN-CD19B, a PBD-based anti-CD19 drug conjugate, for treatment of B-cell malignancies., Blood, 130(18), 2018-2026. doi:10.1182/blood-2017-04-779389 [doi]
Wang, Yongqiang; Huang, Zenghong; Chen, Christopher Z; Liu, Chengfei; Evans, Christopher P; Gao, Allen C; Zhou, Fangjian; Chen, Hong-Wu;, Therapeutic targeting MDR1 expression by ROR? antagonists resensitizes cross-resistant CRPC to taxane via coordinated induction of cell death programs., Molecular cancer therapeutics Vol.10, 2019
Amodio, N., Stamato, M. A., Gulla, A. M., Morelli, E., Romeo, E., Raimondi, L., . . . Tassone, P. (2016)., Therapeutic targeting of miR-29b/HDAC4 epigenetic loop in multiple myeloma., Molecular Cancer Therapeutics, 15(6), 1364-1375. doi:10.1158/1535-7163.MCT-15-0985 [doi]
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