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Imaging

Chen J, Zhao N, Copello V, Ru Y, Burnstein KL, Yang Y., Accurate and Early Metastases Diagnosis in Live Animals With Multimodal X-ray and Optical Imaging, Int J Radiat Oncol Biol Phys. 2023 Feb 1;115(2):511-517. doi: 10.1016/j.ijrobp.2022.07.1832. Epub 2022 Aug 3.
Wei W, Jiang D, Lee HJ, Li M, Kutyreff CJ, Engle JW, Liu J, Cai W., Development and characterization of CD54-targeted immunoPET imaging in solid tumors, Eur J Nucl Med Mol Imaging. 2020 Nov;47(12):2765-2775. doi: 10.1007/s00259-020-04784-0. Epub 2020 Apr 11.

Immunology

Chen M, Kim B, Jarvis MI, Fleury S, Deng S, Nouraein S, Butler S, Lee S, Chambers C, Hodges HC, Szablowski JO, Suh J, Veiseh O., Immune profiling of adeno-associated virus response identifies B cell-specific targets that enable vector re-administration in mice, Gene Ther. 2022 Nov 14. doi: 10.1038/s41434-022-00371-0. Online ahead of print.
Britt NM, Poston MD, Garbe CG, Miller MK, Peeters LD, Wills LJ, Schweitzer JB, Brown RW, Hoover DB., Localization of NGF expression in mouse spleen and salivary gland: Relevance to pleotropic functions, J Neuroimmunol. 2022 May 15;366:577846. doi: 10.1016/j.jneuroim.2022.577846. Epub 2022 Mar 13.
Nagashima H, Mahlakõiv T, Shih HY, Davis FP, Meylan F, Huang Y, Harrison OJ, Yao C, Mikami Y, Urban JF Jr, Caron KM, Belkaid Y, Kanno Y, Artis D, O'Shea JJ., Neuropeptide CGRP Limits Group 2 Innate Lymphoid Cell Responses and Constrains Type 2 Inflammation, Immunity. 2019 Oct 15;51(4):682-695.e6.

Immunotherapy

Wei W, Liu Q, Jiang D, Zhao H, Kutyreff CJ, Engle JW, Liu J, Cai W., Tissue Factor-Targeted ImmunoPET Imaging and Radioimmunotherapy of Anaplastic Thyroid Cancer, Adv Sci (Weinh). 2020 May 17;7(13):1903595. doi: 10.1002/advs.201903595. eCollection 2020 Jul.

Neuropathology

Cheng H, Deaton LM, Qiu M, Ha S, Pacoma R, Lao J, Tolley V, Moran R, Keeton A, Lamb JR, Fathman J, Walker JR, Schumacher AM., Tau overexpression exacerbates neuropathology after repeated mild head impacts in male mice., 2020 Feb;134:104683.

Oncology

DeStefanis, Rebecca Anna; DeZeeuw, Alyssa; Sha, Gioia; Olson, Autumn; Anderson, Samantha J.; Babiarz, Christopher P.; Pasch, Cheri A.; Clipson, Linda; Deming, Dustin A., Abstract 1944: Navitoclax enhances the efficacy of copanlisib predominantly through inhibition of BCLxL in PIK3CA mutant colorectal cancer, Cancer Research. 2021.
Wang Y, Li W, Li Z, Mo F, Chen Y, Iida M, Wheeler DL, Hu Q., Active recruitment of anti-PD-1-conjugated platelets through tumor-selective thrombosis for enhanced anticancer immunotherapy, Sci Adv. 2023 Mar 29;9(13):eadf6854. doi: 10.1126/sciadv.adf6854. Epub 2023 Mar 29.
Kakouratos, Christos; Kalamida, Dimitra; Lamprou, Ioannis; Xanthopoulou, Erasmia; Nanos, Christos; Giatromanolaki, Alexandra; Koukourakis, Michael I., Apalutamide radio-sensitisation of prostate cancer, British Journal of Cancer. 2021.
Longtine, Mark; Shim, Kyuhwan; Wahl, Richard, Biodistribution of 89Zr-ofatumumab and 177Lu-ofatumumab as a Theranostic Pair for Lymphoma, Journal of Nuclear Medicine. 2021.
Sharma S, Wu SY, Jimenez H, Xing F, Zhu D, Liu Y, Wu K, Tyagi A, Zhao D, Lo HW, Metheny-Barlow L, Sun P, Bourland JD, Chan MD, Thomas A, Barbault A, D'Agostino RB, Whitlow CT, Kirchner V, Blackman C, Pasche B, Watabe K, Ca(2+) and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF., EBioMedicine. 2019 Jun;44:194-208.
Nolting, S., Combination targeted therapies for malignant tumours – towards precision medicine, Endocrine Abstracts (2020) 70 S1.2 | DOI: 10.1530/endoabs.70.S1.2
Shim K, Longtine MS, Abou DS, Hoegger MJ, Laforest RS, Thorek DL, Wahl RL., Cure of disseminated human lymphoma with [177Lu]Lu-ofatumumab in a preclinical model, J Nucl Med. 2022 Nov 10:jnumed.122.264816. doi: 10.2967/jnumed.122.264816
Longtine, M. S., Shim, K., Hoegger, M. J., Benabdallah, N., Abou, D. S., Thorek, D. L. J., & Wahl, R. L., Cure of Disseminated Human Lymphoma with [225Ac]Ac-Ofatumumab in a Preclinical Model, Society of Nuclear Medicine, 64(6), 924–931. https://doi.org/10.2967/jnumed.122.265167
Tarab-Ravski, D., Hazan-Halevy, I., Goldsmith, M., Stotsky-Oterin, L., Breier, D., Naidu, G. S., Aitha, A., Diesendruck, Y., Ng, B. D., Barsheshet, H., Berger, T., Vaxman, I., Raanani, P., & Peer, D., Delivery of Therapeutic RNA to the Bone Marrow in Multiple Myeloma Using CD38-Targeted Lipid Nanoparticles, Advanced science (Weinheim, Baden-Wurttemberg, Germany), 10(21), e2301377. https://doi.org/10.1002/advs.202301377
Kostecki KL, Iida M, Wiley AL, Kimani S, Mehall B, Tetreault K, Alexandridis R, Yu M, Hong S, Salgia R, Bruce JY, Birge RB, Harari PM, Wheeler DL., Dual Axl/MerTK inhibitor INCB081776 creates a proinflammatory tumor immune microenvironment and enhances anti-PDL1 efficacy in head and neck cancer, Head Neck. 2023 May;45(5):1255-1271. doi: 10.1002/hed.27340. Epub 2023 Mar 20.
Abou, Diane S.; Fears, Amanda; Summer, Lucy; Longtine, Mark; Benabdallah, Nadia; Riddle, Ryan C.; Ulmert, David; Michalski, Jeff; Wahl, Richard L.; Chesner, Denise; Doucet, Michele; Zachos, Nicholas; Simons, Brian; Thorek, Daniel LJ, Improved Radium-223 Therapy with Combination Epithelial Sodium Channel Blockade, Journal of Nuclear Medicine. 2021.
Aiken TJ, Erbe AK, Zebertavage L, Komjathy D, Feils AS, Rodriguez M, Stuckwisch A, Gillies SD, Morris ZS, Birstler J, Rakhmilevich AL, Sondel PM., Mechanism of effective combination radio-immunotherapy against 9464D-GD2, an immunologically cold murine neuroblastoma, J Immunother Cancer. 2022 May;10(5):e004834. doi: 10.1136/jitc-2022-004834.
Grisaru-Tal, Sharon; Dulberg, Shai; Beck, Lir; Zhang, Chunyan; Itan, Michal; Hediyeh-zadeh, Soroor; Caldwell, Julie; Rozenberg, Perri; Dolitzky, Avishay; Avlas, Shmuel; Hazut, Inbal; Gordon, Yaara; Shani, Ophir; Tsuriel, Shlomo; Gerlic, Motti; Erez, Neta; Jacquelot, Nicolas; Belz, Gabrielle T.; Rothenberg, Marc E.; Davis, Melissa J.; Yu, Hua; Geiger, Tamar; Madi, Asaf; Munitz, Ariel, Metastasis-Entrained Eosinophils Enhance Lymphocyte-Mediated Antitumor Immunity, Cancer Research. 2021.
Hunihan L, Zhao D, Lazowski H, Li M, Qian Y, Abriola L, Surovtseva YV, Muthusamy V, Tanoue LT, Rothberg BEG, Schalper KA, Herbst RS, Wilson FH., RASGRF1 Fusions Activate Oncogenic RAS Signaling and Confer Sensitivity to MEK Inhibition, Clin Cancer Res. 2022 Jul 15;28(14):3091-3103. doi: 10.1158/1078-0432.CCR-21-4291.
Wang Z, Muthusamy V, Petrylak DP, Anderson KS., Tackling FGFR3-driven bladder cancer with a promising synergistic FGFR/HDAC targeted therapy, NPJ Precis Oncol. 2023 Jul 21;7(1):70. doi: 10.1038/s41698-023-00417-5.
Maaland AF, Saidi A, Torgue J, Heyerdahl H, Stallons TAR, Kolstad A, Dahle J., Targeted alpha therapy for chronic lymphocytic leukaemia and non-Hodgkin's lymphoma with the anti-CD37 radioimmunoconjugate 212Pb-NNV003, PLoS One. 2020 Mar 18;15(3):e0230526. doi: 10.1371/journal.pone.0230526. eCollection 2020.
Apostolidi, Maria; Vathiotis, Ioannis A.; Muthusamy, Viswanathan; Gaule, Patricia; Gassaway, Brandon M.; Rimm, David L.; Rinehart, Jesse, Targeting Pyruvate Kinase M2 Phosphorylation Reverses Aggressive Cancer Phenotypes, Cancer Research. 2021.
Hong, J., Maacha, S., & Belkhiri, A. (2018), Transcriptional upregulation of c-MYC by AXL confers epirubicin resistance in esophageal adenocarcinoma., Molecular Oncology, doi:10.1002/1878-0261.12395 [doi]

Other

Sánchez-del-Campo, Luis; Martí-Díaz, Román; Montenegro, María F.; González-Guerrero, Rebeca; Hernández-Caselles, Trinidad; Martínez-Barba, Enrique; Pińero-Madrona, Antonio; Cabezas-Herrera, Juan; Goding, Colin R.; Rodríguez-López, José Neptuno, MITF induces escape from innate immunity in melanoma, Journal of Experimental & Clinical Cancer Research. 2021.

Stem cells

Crowley L, Cambuli F, Aparicio L, Shibata M, Robinson BD, Xuan S, Li W, Hibshoosh H, Loda M, Rabadan R, Shen MM., A single-cell atlas of the mouse and human prostate reveals heterogeneity and conservation of epithelial progenitors, Elife. 2020 Sep 11;9:e59465. doi: 10.7554/eLife.59465.

Tumor biology

Hoegger, Mark J.; Longtine, Mark S.; Shim, Kyuhwan; Wahl, Richard L., Bioluminescent Tumor Signal Is Mouse Strain and Pelt Color Dependent: Experience in a Disseminated Lymphoma Model, Molecular Imaging and Biology. 2021.
Li Y, Cheng Q, Xiong Z, Paiboonrungruang C, Adekoya T, Li Y, Chen X., Lymphatic Drainage System and Lymphatic Metastasis of Cancer Cells in the Mouse Esophagus, Dig Dis Sci. 2022 Jun 21. doi: 10.1007/s10620-022-07586-6. Online ahead of print.
Xu Z, Murad N, Malawsky D, Tao R, Rivero-Hinojosa S, Holdhof D, Schüller U, Zhang P, Lazarski C, Rood BR, Packer R, Gershon T, Pei Y., OLIG2 Is a Determinant for the Relapse of MYC-Amplified Medulloblastoma, Clin Cancer Res. 2022 Oct 3;28(19):4278-4291. doi: 10.1158/1078-0432.CCR-22-0527.

Tumor growth

Hong J, Maacha S, Pidkovka N, Bates A, Salaria SN, Washington MK, Belkhiri A., AXL Promotes Metformin-Induced Apoptosis Through Mediation of Autophagy by Activating ROS-AMPK-ULK1 Signaling in Human Esophageal Adenocarcinoma, Front Oncol. 2022 Jul 22;12:903874. doi: 10.3389/fonc.2022.903874. eCollection 2022.
Ganaie AA, Parray A, Hussain T, Shabaneh A, Jamroze A, Ferrari MG, Wang L, Liao DJ, Koochekpour S, Nanda S, Wang J, Deng Y, Gradilone SA, Hinchcliffe EH, Konety BR, Saleem M., Identifying the Role of Intestine Specific Homeobox Gene ISX in Hypoxia and Disease Progression., Transl Oncol. 2019 Aug;12(8):1056-1071.
Page, A., Ortega, A., Alameda, J. P., Navarro, M., Paramio, J. M., Saiz-Pardo, M., ... & Casanova, M. L. (2019)., IKKÎą promotes the progression and metastasis of non-small cell lung cancer independently of its subcellular localization, Computational and Structural Biotechnology Journal, 17, 251-262.
Davenport, Mackenzie L.; Echols, John B.; Silva, Austin D.; Anderson, Joshua C.; Owens, Philip; Yates, Clayton; Wei, Qing; Harada, Shuko; Hurst, Douglas R.; Edmonds, Mick D., miR-31 Displays Subtype Specificity in Lung Cancer, Cancer Research. 2021.
Jiménez-Segovia A, Mota A, Rojo-Sebastián A, Barrocal B, Rynne-Vidal A, García-Bermejo ML, Gómez-Bris R, Hawinkels LJAC, Sandoval P, Garcia-Escudero R, López-Cabrera M, Moreno-Bueno G, Fresno M, Stamatakis K, Prostaglandin F 2Îą-induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity., Neoplasia. 2019 Nov;21(11):1073-1084.
Davenport ML, Davis MR, Davenport BN, Crossman DK, Hall A, Pike J, Harada S, Hurst DR, Edmonds MD., Suppression of SIN3A by miR-183 Promotes Breast Cancer Metastasis, Mol Cancer Res. 2022 Jun 3;20(6):883-894. doi: 10.1158/1541-7786.MCR-21-0508.

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