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    Oncology

    Abbruzzese, C., Catalogna, G., Gallo, E., di Martino, S., Mileo, A. M., Carosi, M., . . . Paggi, M. G. (2017).,The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme.,Oncotarget, 8(67), 110743-110755. doi:10.18632/oncotarget.22500 [doi]
    Adam, C., Baeurle, A., Brodsky, J. L., Wipf, P., Schrama, D., Becker, J. C., & Houben, R. (2014),The HSP70 modulator MAL3-101 inhibits merkel cell carcinoma.,PloS One, 9(4), e92041. doi:10.1371/journal.pone.0092041 [doi]
    Airoldi, I., Di Carlo, E., Cocco, C., Caci, E., Cilli, M., Sorrentino, C., . . . Pistoia, V. (2009).,IL-12 can target human lung adenocarcinoma cells and normal bronchial epithelial cells surrounding tumor lesions.,PloS One, 4(7), e6119. doi:10.1371/journal.pone.0006119 [doi]
    Airoldi, I., Tupone, M. G., Esposito, S., Russo, M. V., Barbarito, G., Cipollone, G., & Di Carlo, E. (2015).,Interleukin-27 re-educates intratumoral myeloid cells and down-regulates stemness genes in non-small cell lung cancer.,Oncotarget, 6(6), 3694-3708. doi:2797 [pii]
    Baertsch, M. A., Leber, M. F., Bossow, S., Singh, M., Engeland, C. E., Albert, J., . . . Ungerechts, G. (2014),MicroRNA-mediated multi-tissue detargeting of oncolytic measles virus.,Cancer Gene Therapy, 21(9), 373-380. doi:10.1038/cgt.2014.40 [doi]
    Balvers, R. K., Belcaid, Z., van den Hengel, S. K., Kloezeman, J., de Vrij, J., Wakimoto, H., . . . Lamfers, M. L. (2014).,Locally-delivered T-cell-derived cellular vehicles efficiently track and deliver adenovirus delta24-RGD to infiltrating glioma.,Viruses, 6(8), 3080-3096. doi:10.3390/v6083080 [doi]
    Boer, J. C., Domanska, U. M., Timmer-Bosscha, H., Boer, I. G., de Haas, C. J., Joseph, J. V., . . . Walenkamp, A. M. (2013),Inhibition of formyl peptide receptor in high-grade astrocytoma by CHemotaxis inhibitory protein of S. aureus.,British Journal of Cancer, 108(3), 587-596. doi:10.1038/bjc.2012.603 [doi]
    Boi, M., Gaudio, E., Bonetti, P., Kwee, I., Bernasconi, E., Tarantelli, C., . . . Bertoni, F. (2015).,The BET bromodomain inhibitor OTX015 affects pathogenetic pathways in preclinical B-cell tumor models and synergizes with targeted drugs.,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 21(7), 1628-1638. doi:10.1158/1078-0432.CCR-14-1561 [doi]
    Boi, M., Gaudio, E., Bonetti, P., Kwee, I., Bernasconi, E., Tarantelli, C., . . . Bertoni, F. (2015).,The BET bromodomain inhibitor OTX015 affects pathogenetic pathways in preclinical B-cell tumor models and synergizes with targeted drugs.,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 21(7), 1628-1638. doi:10.1158/1078-0432.CCR-14-1561 [doi]
    Bruckheimer, E. M., Fazenbaker, C. A., Gallagher, S., Mulgrew, K., Fuhrmann, S., Coffman, K. T., . . . Coats, S. (2009).,Antibody-dependent cell-mediated cytotoxicity effector-enhanced EphA2 agonist monoclonal antibody demonstrates potent activity against human tumors.,Neoplasia (New York, N.Y.), 11(6), 509-17, 2 p following 517.
    Buoncervello, M., Romagnoli, G., Buccarelli, M., Fragale, A., Toschi, E., Parlato, S., . . . Gabriele, L. (2016),IFN-alpha potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer.,Oncotarget, 7(18), 26361-26373. doi:10.18632/oncotarget.8379 [doi]
    Burns, T. F., Dobromilskaya, I., Murphy, S. C., Gajula, R. P., Thiyagarajan, S., Chatley, S. N., . . . Rudin, C. M. (2013).,Inhibition of TWIST1 leads to activation of oncogene-induced senescence in oncogene-driven non-small cell lung cancer,Molecular Cancer Research : MCR, 11(4), 329-338. doi:10.1158/1541-7786.MCR-12-0456 [doi]
    Chao, M. W., Chu, P. C., Chuang, H. C., Shen, F. H., Chou, C. C., Hsu, E. C., . . . Chen, C. S. (2016).,Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability.,Oncotarget, 7(2), 1796-1807. doi:10.18632/oncotarget.6427 [doi]
    Cheng, K. W., Mattheolabakis, G., Wong, C. C., Ouyang, N., Huang, L., Constantinides, P. P., & Rigas, B. (2012).,Topical phospho-sulindac (OXT-328) is effective in the treatment of non-melanoma skin cancer.,International Journal of Oncology, 41(4), 1199-1203. doi:10.3892/ijo.2012.1577 [doi]
    Cocco, C., Giuliani, N., Di Carlo, E., Ognio, E., Storti, P., Abeltino, M., . . . Airoldi, I. (2010),Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma.,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 16(16), 4188-4197. doi:10.1158/1078-0432.CCR-10-0173 [doi]
    Cosco, D., Cilurzo, F., Maiuolo, J., Federico, C., Di Martino, M. T., Cristiano, M. C., . . . Paolino, D. (2015).,Delivery of miR-34a by chitosan/PLGA nanoplexes for the anticancer treatment of multiple myeloma.,Scientific Reports, 5, 17579. doi:10.1038/srep17579 [doi]
    Cosco, D., Paolino, D., De Angelis, F., Cilurzo, F., Celia, C., Di Marzio, L., . . . Fresta, M. (2015),Aqueous-core PEG-coated PLA nanocapsules for an efficient entrapment of water soluble anticancer drugs and a smart therapeutic response,European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V, 89, 30-39. doi:10.1016/j.ejpb.2014.11.012 [doi]
    Dahlmann, M., & Stein, U. (2015).,RNA interference for antimetastatic therapy.,Methods in Molecular Biology (Clifton, N.J.), 1317, 153-165. doi:10.1007/978-1-4939-2727-2_10 [doi]
    D'Alesio, C., Punzi, S., Cicalese, A., Fornasari, L., Furia, L., Riva, L., . . . Lanfrancone, L. (2016).,RNAi screens identify CHD4 as an essential gene in breast cancer growth,Oncotarget, 7(49), 80901-80915. doi:10.18632/oncotarget.12646 [doi]
    Damelin, M., Bankovich, A., Park, A., Aguilar, J., Anderson, W., Santaguida, M., . . . Dylla, S. J. (2015).,Anti-EFNA4 calicheamicin conjugates effectively target triple-negative breast and ovarian tumor-initiating cells to result in sustained tumor regressions,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 21(18), 4165-4173. doi:10.1158/1078-0432.CCR-15-0695 [doi]
    Davidi, S., Fremder, E., Kan, T., Raviv, Z., Timaner, M., Karin, N., . . . Shaked, Y. (2017),he antiangiogenic role of the pro-inflammatory cytokine interleukin-31.,Oncotarget, 8(10), 16430-16444. doi:10.18632/oncotarget.14857 [doi]
    Dey, J., Deckwerth, T. L., Kerwin, W. S., Casalini, J. R., Merrell, A. J., Grenley, M. O., . . . Klinghoffer, R. A. (2017).,Voruciclib, a clinical stage oral CDK9 inhibitor, represses MCL-1 and sensitizes high-risk diffuse large B-cell lymphoma to BCL2 inhibition,Scientific Reports, 7(1), 18007-017-18368-w. doi:10.1038/s41598-017-18368-w [doi]
    Di Martino, M. T., Gulla, A., Gallo Cantafio, M. E., Altomare, E., Amodio, N., Leone, E., . . . Tassone, P. (2014,In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells.,PloS One, 9(2), e89659. doi:10.1371/journal.pone.0089659 [doi]
    Di Meo, C., Cilurzo, F., Licciardi, M., Scialabba, C., Sabia, R., Paolino, D., . . . Matricardi, P. (2015).,Polyaspartamide-doxorubicin conjugate as potential prodrug for anticancer therapy.,Pharmaceutical Research, 32(5), 1557-1569. doi:10.1007/s11095-014-1557-2 [doi]
    Dold, C., Rodriguez Urbiola, C., Wollmann, G., Egerer, L., Muik, A., Bellmann, L., . . . von Laer, D. (2016).,Application of interferon modulators to overcome partial resistance of human ovarian cancers to VSV-GP oncolytic viral therapy.,Molecular Therapy Oncolytics, 3, 16021. doi:10.1038/mto.2016.21 [doi]
    Fareh, M., Turchi, L., Virolle, V., Debruyne, D., Almairac, F., de-la-Forest Divonne, S., . . . Virolle, T. (2012).,The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network.,Cell Death and Differentiation, 19(2), 232-244. doi:10.1038/cdd.2011.89 [doi]
    Fischer, M. M., Cancilla, B., Yeung, V. P., Cattaruzza, F., Chartier, C., Murriel, C. L., . . . Hoey, T. (2017).,WNT antagonists exhibit unique combinatorial antitumor activity with taxanes by potentiating mitotic cell death,Science Advances, 3(6), e1700090. doi:10.1126/sciadv.1700090 [doi]
    Fischer, M. M., Yeung, V. P., Cattaruzza, F., Hussein, R., Yen, W. C., Murriel, C., . . . Hoey, T. (2017).,RSPO3 antagonism inhibits growth and tumorigenicity in colorectal tumors harboring common wnt pathway mutations.,Scientific Reports, 7(1), 15270-017-15704-y. doi:10.1038/s41598-017-15704-y [doi]
    Friedrich, M., Henn, A., Raum, T., Bajtus, M., Matthes, K., Hendrich, L., . . . Rattel, B. (2014).,Preclinical characterization of AMG 330, a CD3/CD33-bispecific T-cell-engaging antibody with potential for treatment of acute myelogenous leukemia.,Molecular Cancer Therapeutics, 13(6), 1549-1557. doi:10.1158/1535-7163.MCT-13-0956 [doi]
    Galuppo, R., Maynard, E., Shah, M., Daily, M. F., Chen, C., Spear, B. T., & Gedaly, R. (2014).,Synergistic inhibition of HCC and liver cancer stem cell proliferation by targeting RAS/RAF/MAPK and WNT/beta-catenin pathways,Anticancer Research, 34(4), 1709-1713. doi:34/4/1709 [pii]
    Garg, G., Gibbs, J., Belt, B., Powell, M. A., Mutch, D. G., Goedegebuure, P., . . . Spitzer, D. (2014).,Novel treatment option for MUC16-positive malignancies with the targeted TRAIL-based fusion protein meso-TR3.,BMC Cancer, 14, 35-2407-14-35. doi:10.1186/1471-2407-14-35 [doi]
    Gatt, S., & Dagan, A. (2012),Cancer and sphingolipid storage disease therapy using novel synthetic analogs of sphingolipids,Chemistry and Physics of Lipids, 165(4), 462-474. doi:10.1016/j.chemphyslip.2012.02.006 [doi]
    Gaudio, E., Tarantelli, C., Kwee, I., Barassi, C., Bernasconi, E., Rinaldi, A., . . . Bertoni, F. (2016).,Combination of the MEK inhibitor pimasertib with BTK or PI3K-delta inhibitors is active in preclinical models of aggressive lymphomas.,Annals of Oncology : Official Journal of the European Society for Medical Oncology, 27(6), 1123-1128. doi:10.1093/annonc/mdw131 [doi]
    Gaudio, E., Tarantelli, C., Ponzoni, M., Odore, E., Rezai, K., Bernasconi, E., . . . Bertoni, F. (2016).,Bromodomain inhibitor OTX015 (MK-8628) combined with targeted agents shows strong in vivo antitumor activity in lymphoma,Oncotarget, 7(36), 58142-58147. doi:10.18632/oncotarget.10983 [doi]
    Gedaly, R., Galuppo, R., Daily, M. F., Shah, M., Maynard, E., Chen, C., . . . Spear, B. T. (2014).,Targeting the Wnt/beta-catenin signaling pathway in liver cancer stem cells and hepatocellular carcinoma cell lines with FH535.,PloS One, 9(6), e99272. doi:10.1371/journal.pone.0099272 [doi]
    Giovannini, C., Baglioni, M., Baron Toaldo, M., Ventrucci, C., D'Adamo, S., Cipone, M., . . . Bolondi, L. (2013).,Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma.,Oncotarget, 4(10), 1618-1631. doi:1221 [pii]
    Haas, T. L., Sciuto, M. R., Brunetto, L., Valvo, C., Signore, M., Fiori, M. E., . . . De Maria, R. (2017).,ntegrin alpha7 is a functional marker and potential therapeutic target in glioblastoma,Cell Stem Cell, 21(1), 35-50.e9. doi:S1934-5909(17)30137-6 [pii]
    Hassler, M. R., Klisaroska, A., Kollmann, K., Steiner, I., Bilban, M., Schiefer, A. I., . . . Egger, G. (2012).,Antineoplastic activity of the DNA methyltransferase inhibitor 5-aza-2'-deoxycytidine in anaplastic large cell lymphoma.,Biochimie, 94(11), 2297-2307. doi:10.1016/j.biochi.2012.05.029 [doi]
    He, M., Tan, B., Vasan, K., Yuan, H., Cheng, F., Ramos da Silva, S., . . . Gao, S. J. (2017).,SIRT1 and AMPK pathways are essential for the proliferation and survival of primary effusion lymphoma cells,The Journal of Pathology, 242(3), 309-321. doi:10.1002/path.4905 [doi]
    Hofmann, M., McCormack, E., Mujic, M., Rossberg, M., Bernd, A., Bereiter-Hahn, J., . . . Kippenberger, S. (2009).,Increased plasma colloid osmotic pressure facilitates the uptake of therapeutic macromolecules in a xenograft tumor model,Neoplasia (New York, N.Y.), 11(8), 812-822.
    Kim, S., Jin, H., Seo, H. R., Lee, H. J., & Lee, Y. S. (2018).,Regulating BRCA1 protein stability by cathepsin S-mediated ubiquitin degradation.,Cell Death and Differentiation, doi:10.1038/s41418-018-0153-0 [doi]
    Kolev, V. N., Wright, Q. G., Vidal, C. M., Ring, J. E., Shapiro, I. M., Ricono, J., . . . Xu, Q. (2015).,PI3K/mTOR dual inhibitor VS-5584 preferentially targets cancer stem cells.,null
    Komar-Stossel, C., Gross, E., Dery, E., Corchia, N., Meir, K., Fried, I., & Abramovitch, R. (2014),TL-118 and gemcitabine drug combination display therapeutic efficacy in a MYCN amplified orthotopic neuroblastoma murine model--evaluation by MRI,PloS One, 9(3), e90224. doi:10.1371/journal.pone.0090224 [doi]
    Lamanuzzi, A., Saltarella, I., Desantis, V., Frassanito, M. A., Leone, P., Racanelli, V., . . . Ria, R. (2018).,Inhibition of mTOR complex 2 restrains tumor angiogenesis in multiple myeloma.,Oncotarget, 9(29), 20563-20577. doi:10.18632/oncotarget.25003 [doi]
    Laurent, S., Queirolo, P., Boero, S., Salvi, S., Piccioli, P., Boccardo, S., . . . Pistillo, M. P. (2013).,The engagement of CTLA-4 on primary melanoma cell lines induces antibody-dependent cellular cytotoxicity and TNF-alpha production.,Journal of Translational Medicine, 11, 108-5876-11-108. doi:10.1186/1479-5876-11-108 [doi]
    Leone, E., Morelli, E., Di Martino, M. T., Amodio, N., Foresta, U., Gulla, A., . . . Tassone, P. (2013).,Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 19(8), 2096-2106. doi:10.1158/1078-0432.CCR-12-3325 [doi]
    Li, X., Wu, J. B., Li, Q., Shigemura, K., Chung, L. W., & Huang, W. C. (2016).,SREBP-2 promotes stem cell-like properties and metastasis by transcriptional activation of c-myc in prostate cancer.,Oncotarget, 7(11), 12869-12884. doi:10.18632/oncotarget.7331 [doi]
    Litzenburger, B. C., Creighton, C. J., Tsimelzon, A., Chan, B. T., Hilsenbeck, S. G., Wang, T., . . . Lee, A. V. (2011),High IGF-IR activity in triple-negative breast cancer cell lines and tumorgrafts correlates with sensitivity to anti-IGF-IR therapy.,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 17(8), 2314-2327. doi:10.1158/1078-0432.CCR-10-1903 [doi]
    Liu, R., Shi, P., Nie, Z., Liang, H., Zhou, Z., Chen, W., . . . Chen, C. (2016).,Mifepristone suppresses basal triple-negative breast cancer stem cells by down-regulating KLF5 expression.,Theranostics, 6(4), 533-544. doi:10.7150/thno.14315 [doi]
    Londono-Joshi, A. I., Oliver, P. G., Li, Y., Lee, C. H., Forero-Torres, A., LoBuglio, A. F., & Buchsbaum, D. J. (2012).,Basal-like breast cancer stem cells are sensitive to anti-DR5 mediated cytotoxicity,Breast Cancer Research and Treatment, 133(2), 437-445. doi:10.1007/s10549-011-1763-0 [doi]
    Lu, Y., Liu, Y., Oeck, S., & Glazer, P. M. (2018).,Hypoxia promotes resistance to EGFR inhibition in NSCLC cells via the histone demethylases, LSD1 and PLU-1.,Molecular Cancer Research : MCR, 16(10), 1458-1469. doi:10.1158/1541-7786.MCR-17-0637 [doi]
    Lynam-Lennon, N., Heavey, S., Sommerville, G., Bibby, B. A., Ffrench, B., Quinn, J., . . . Maher, S. G. (2017).,MicroRNA-17 is downregulated in esophageal adenocarcinoma cancer stem-like cells and promotes a radioresistant phenotype,Oncotarget, 8(7), 11400-11413. doi:10.18632/oncotarget.13940 [doi]
    Melis, M. H., Simpson, K. L., Dovedi, S. J., Welman, A., MacFarlane, M., Dive, C., . . . Illidge, T. M. (2013).,Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response,Cell Death and Differentiation, 20(5), 765-773. doi:10.1038/cdd.2013.8 [doi]
    Moschetta, M., Basile, A., Ferrucci, A., Frassanito, M. A., Rao, L., Ria, R., . . . Vacca, A. (2013).,Novel targeting of phospho-cMET overcomes drug resistance and induces antitumor activity in multiple myeloma.,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 19(16), 4371-4382. doi:10.1158/1078-0432.CCR-13-0039 [doi]
    Ordonez, J. L., Amaral, A. T., Carcaboso, A. M., Herrero-Martin, D., del Carmen Garcia-Macias, M., Sevillano, V., . . . de Alava, E. (2015,The PARP inhibitor olaparib enhances the sensitivity of ewing sarcoma to trabectedin,Oncotarget, 6(22), 18875-18890. doi:10.18632/oncotarget.4303 [doi]
    Paolino, D., Cosco, D., Celano, M., Moretti, S., Puxeddu, E., Russo, D., & Fresta, M. (2013).,Gemcitabine-loaded biocompatible nanocapsules for the effective treatment of human cancer,Nanomedicine (London, England), 8(2), 193-201. doi:10.2217/nnm.12.101 [doi]
    Paolino, D., Licciardi, M., Celia, C., Giammona, G., Fresta, M., & Cavallaro, G. (2012).,Folate-targeted supramolecular vesicular aggregates as a new frontier for effective anticancer treatment in in vivo model.,European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Fur Pharmazeutische Verfahrenstechnik e.V, 82(1), 94-102. doi:10.1016/j.ejpb.2012.06.001 [doi]
    Patyna, S., Laird, A. D., Mendel, D. B., O'farrell, A. M., Liang, C., Guan, H., . . . Hu-Lowe, D. (2006).,SU14813: A novel multiple receptor tyrosine kinase inhibitor with potent antiangiogenic and antitumor activity,Molecular Cancer Therapeutics, 5(7), 1774-1782. doi:5/7/1774 [pii]
    Pleniceanu, O., Shukrun, R., Omer, D., Vax, E., Kanter, I., Dziedzic, K., . . . Dekel, B. (2017).,Peroxisome proliferator-activated receptor gamma (PPARgamma) is central to the initiation and propagation of human angiomyolipoma, suggesting its potential as a therapeutic target,EMBO Molecular Medicine, 9(4), 508-530. doi:10.15252/emmm.201506111 [doi]
    Raimondi, L., Amodio, N., Di Martino, M. T., Altomare, E., Leotta, M., Caracciolo, D., . . . Tassone, P. (2014),Targeting of multiple myeloma-related angiogenesis by miR-199a-5p mimics: In vitro and in vivo anti-tumor activity,Oncotarget, 5(10), 3039-3054. doi:1747 [pii]
    Rao, L., De Veirman, K., Giannico, D., Saltarella, I., Desantis, V., Frassanito, M. A., . . . Vacca, A. (2018).,Targeting angiogenesis in multiple myeloma by the VEGF and HGF blocking DARPin((R)) protein MP0250: A preclinical study,Oncotarget, 9(17), 13366-13381. doi:10.18632/oncotarget.24351 [doi]
    Rodriguez-Barrueco, R., Yu, J., Saucedo-Cuevas, L. P., Olivan, M., Llobet-Navas, D., Putcha, P., . . . Silva, J. M. (2015).,Inhibition of the autocrine IL-6-JAK2-STAT3-calprotectin axis as targeted therapy for HR-/HER2+ breast cancers,Genes & Development, 29(15), 1631-1648. doi:10.1101/gad.262642.115 [doi]
    Sabatino, M. A., Geroni, C., Ganzinelli, M., Ceruti, R., & Broggini, M. (2013).,Zebularine partially reverses GST methylation in prostate cancer cells and restores sensitivity to the DNA minor groove binder brostallicin,Epigenetics, 8(6), 656-665. doi:10.4161/epi.24916 [doi]
    Shin, D. Y., Kim, A., Kang, H. J., Park, S., Kim, D. W., & Lee, S. S. (2015).,Histone deacetylase inhibitor romidepsin induces efficient tumor cell lysis via selective down-regulation of LMP1 and c-myc expression in EBV-positive diffuse large B-cell lymphoma,Cancer Letters, 364(2), 89-97. doi:10.1016/j.canlet.2015.03.016 [doi]
    Shir, A., Ogris, M., Roedl, W., Wagner, E., & Levitzki, A. (2011),EGFR-homing dsRNA activates cancer-targeted immune response and eliminates disseminated EGFR-overexpressing tumors in mice,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 17(5), 1033-1043. doi:10.1158/1078-0432.CCR-10-1140 [doi]
    Signore, M., Buccarelli, M., Pilozzi, E., De Luca, G., Cappellari, M., Fanciulli, M., . . . Ricci-Vitiani, L. (2016).,UCN-01 enhances cytotoxicity of irinotecan in colorectal cancer stem-like cells by impairing DNA damage response,Oncotarget, 7(28), 44113-44128. doi:10.18632/oncotarget.9859 [doi]
    Smit, J. K., Faber, H., Niemantsverdriet, M., Baanstra, M., Bussink, J., Hollema, H., . . . Coppes, R. P. (2013).,Prediction of response to radiotherapy in the treatment of esophageal cancer using stem cell markers.,Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology, 107(3), 434-441. doi:10.1016/j.radonc.2013.03.027 [doi]
    Sommer, A., Kopitz, C., Schatz, C. A., Nising, C. F., Mahlert, C., Lerchen, H. G., . . . Kreft, B. (2016).,Preclinical efficacy of the auristatin-based antibody-drug conjugate BAY 1187982 for the treatment of FGFR2-positive solid tumors,Cancer Research, 76(21), 6331-6339. doi:0008-5472.CAN-16-0180 [pii]
    Stafman, L. L., Mruthyunjayappa, S., Waters, A. M., Garner, E. F., Aye, J. M., Stewart, J. E., . . . Beierle, E. A. (2018).,Targeting PIM kinase as a therapeutic strategy in human hepatoblastoma.,Oncotarget, 9(32), 22665-22679. doi:10.18632/oncotarget.25205 [doi]
    Stewart, R., Morrow, M., Hammond, S. A., Mulgrew, K., Marcus, D., Poon, E., . . . McCourt, M. (2015).,Identification and characterization of MEDI4736, an antagonistic anti-PD-L1 monoclonal antibody.,Cancer Immunology Research, 3(9), 1052-1062. doi:10.1158/2326-6066.CIR-14-0191 [doi]
    Sun, L., Zhang, L., Qian, J., Yang, J., Yi, Q., Dong, W., & Wang, M. (2012).,Combination of atiprimod and the proteasome inhibitor bortezomib induces apoptosis of mantle cell lymphoma in vitro and in vivo.,Leukemia Research, 36(3), 363-368. doi:10.1016/j.leukres.2011.09.014 [doi]
    Torres-Guzman, R., Calsina, B., Hermoso, A., Baquero, C., Alvarez, B., Amat, J., . . . Lallena, M. J. (2017).,Preclinical characterization of abemaciclib in hormone receptor positive breast cancer.,Oncotarget, 8(41), 69493-69507. doi:10.18632/oncotarget.17778 [doi]
    Van Impe, K., Bethuyne, J., Cool, S., Impens, F., Ruano-Gallego, D., De Wever, O., . . . Gettemans, J. (2013),A nanobody targeting the F-actin capping protein CapG restrains breast cancer metastasis.,Breast Cancer Research : BCR, 15(6), R116. doi:10.1186/bcr3585 [doi]
    Wang, L., Park, P., La Marca, F., Than, K., Rahman, S., & Lin, C. Y. (2013).,Bone formation induced by BMP-2 in human osteosarcoma cells.,International Journal of Oncology, 43(4), 1095-1102. doi:10.3892/ijo.2013.2030 [doi]
    Wang, L., Park, P., Zhang, H., La Marca, F., Claeson, A., Than, K., . . . Lin, C. Y. (2012).,BMP-2 inhibits tumor growth of human renal cell carcinoma and induces bone formation,International Journal of Cancer.Journal International Du Cancer, 131(8), 1941-1950. doi:10.1002/ijc.27444 [doi]
    Was, H., Barszcz, K., Czarnecka, J., Kowalczyk, A., Bernas, T., Uzarowska, E., . . . Sikora, E. (2017).,Bafilomycin A1 triggers proliferative potential of senescent cancer cells in vitro and in NOD/SCID mice.,Oncotarget, 8(6), 9303-9322. doi:10.18632/oncotarget.14066 [doi]
    Wennier, S. T., Liu, J., Li, S., Rahman, M. M., Mona, M., & McFadden, G. (2012).,Myxoma virus sensitizes cancer cells to gemcitabine and is an effective oncolytic virotherapeutic in models of disseminated pancreatic cancer.,Molecular Therapy : The Journal of the American Society of Gene Therapy, 20(4), 759-768. doi:10.1038/mt.2011.293 [doi]
    Yen, W. C., Fischer, M. M., Hynes, M., Wu, J., Kim, E., Beviglia, L., . . . Hoey, T. (2012),Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-notch signaling in both tumor and vasculature cells.,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 18(19), 5374-5386. doi:10.1158/1078-0432.CCR-12-0736 [doi]
    Zaoui, K., Bossow, S., Grossardt, C., Leber, M. F., Springfeld, C., Plinkert, P. K., . . . Ungerechts, G. (2012).,Chemovirotherapy for head and neck squamous cell carcinoma with EGFR-targeted and CD/UPRT-armed oncolytic measles virus.,Cancer Gene Therapy, 19(3), 181-191. doi:10.1038/cgt.2011.75 [doi]
    Zarrinkar, P. P., Gunawardane, R. N., Cramer, M. D., Gardner, M. F., Brigham, D., Belli, B., . . . Bhagwat, S. S. (2009),AC220 is a uniquely potent and selective inhibitor of FLT3 for the treatment of acute myeloid leukemia (AML).,Blood, 114(14), 2984-2992. doi:10.1182/blood-2009-05-222034 [doi]
    Zhu, C., Cheng, K. W., Ouyang, N., Huang, L., Sun, Y., Constantinides, P., & Rigas, B. (2012).,Phosphosulindac (OXT-328) selectively targets breast cancer stem cells in vitro and in human breast cancer xenografts.,Stem Cells (Dayton, Ohio), 30(10), 2065-2075. doi:10.1002/stem.1139 [doi]
    Aasen, Synnøve Nymark; Espedal, Heidi; Holte, Christopher Florian; Keunen, Olivier; Karlsen, Tine Veronika; Tenstad, Olav; Maherally, Zaynah; Miletic, Hrvoje; Hoang, Tuyen; Eikeland, Anne Vaag; Baghirov, Habib; Olberg, Dag Erlend; Pilkington, Geoffrey John; Sarkar, Gobinda; Jenkins, Robert B; Sundstrøm, Terje; Bjerkvig, Rolf; Thorsen, Frits;,Improved Drug Delivery to Brain Metastases by Peptide-Mediated Permeabilization of the Blood-Brain Barrier.,Molecular cancer therapeutics Vol.18, 2019
    Aasen, Synnøve Nymark; Parajuli, Himalaya; Hoang, Tuyen; Feng, Zichao; Stokke, Krister; Wang, Jiwei; Roy, Kislay; Bjerkvig, Rolf; Knappskog, Stian; Thorsen, Frits;,Effective Treatment of Metastatic Melanoma by Combining MAPK and PI3K Signaling Pathway Inhibitors.,International journal of molecular sciences Vol.20, 2019
    Amodio, Nicola; Gallo Cantafio, Maria Eugenia; Botta, Cirino; Agosti, Valter; Federico, Cinzia; Caracciolo, Daniele; Ronchetti, Domenica; Rossi, Marco; Driessen, Christoph; Neri, Antonino; Tagliaferri, Pierosandro; Tassone, Pierfrancesco;,Replacement of miR-155 Elicits Tumor Suppressive Activity and Antagonizes Bortezomib Resistance in Multiple Myeloma,Cancers Vol.11, 2019
    Badarni, Mai; Prasad, Manu; Balaban, Noa; Zorea, Jonathan; Yegodayev, Ksenia M; Joshua, Ben-Zion; Dinur, Anat Bahat; Grénman, Reidar; Rotblat, Barak; Cohen, Limor; Elkabets, Moshe,Repression of AXL expression by AP-1/JNK blockage overcomes resistance to PI3Ka therapy,JCI insight Vol.5, 2019
    Benguigui, Madeleine; Weitz, Iris S; Timaner, Michael; Kan, Tal; Shechter, Dvir; Perlman, Or; Sivan, Sarit; Raviv, Ziv; Azhari, Haim; Shaked, Yuval;,Copper oxide nanoparticles inhibit pancreatic tumor growth primarily by targeting tumor initiating cells.,Scientific reports Vol.9, 2019
    Falah, Mizied; Rayan, Mahmoud; Rayan, Anwar,A Novel Paclitaxel Conjugate with Higher Efficiency and Lower Toxicity: A New Drug Candidate for Cancer Treatment.,International journal of molecular sciences Vol.20, 2019
    Feng, Yashu; Zhang, Ling; Wu, Jieying; Khadka, Bijay; Fang, Zhigang; Gu, Jiaming; Tang, Baoqiang; Xiao, Ruozhi; Pan, Guangjin; Liu, Jiajun;,CircRNA circ_0000190 inhibits the progression of multiple myeloma through modulating miR-767-5p/MAPK4 pathway.,Journal of experimental & clinical cancer research : CR Vol.38, 2019
    Hammer, Stefanie; Hagemann, Urs B; Zitzmann-Kolbe, Sabine; Larsen, Aasmund; Ellingsen, Christine; Geraudie, Solene; Grant, Derek; Indrevoll, Baard; Smeets, Roger; von Ahsen, Oliver; Kristian, Alexander; Lejeune, Pascale; Hennekes, Hartwig; Karlsson, Jenny; Bjerke, Roger M; Ryan, Olav B; Cuthbertson, Alan S; Mumberg, Dominik;,Preclinical efficacy of a PSMA-targeted thorium-227 conjugate (PSMA-TTC), a targeted alpha therapy for prostate cancer.,Clinical cancer research : an official journal of the American Association for Cancer Research Vol.9, 2019
    Hoogi, Shiran; Eisenberg, Vasyl; Mayer, Shimrit; Shamul, Astar; Barliya, Tilda; Cohen, Cyrille J,A TIGIT-based chimeric co-stimulatory switch receptor improves T-cell anti-tumor function,Journal for immunotherapy of cancer Vol.7, 2019
    Krishnamoorthy, Gnana P; Davidson, Natalie R; Leach, Steven D; Zhao, Zhen; Lowe, Scott W; Lee, Gina; Landa, Iňigo; Nagarajah, James; Saqcena, Mahesh; Singh, Kamini; Wendel, Hans-Guido; Dogan, Snjezana; Tamarapu, Prasanna P; Blenis, John; Ghossein, Ronald A; Knauf, Jeffrey A; Rätsch, Gunnar; Fagin, James A,EIF1AX and RAS Mutations Cooperate to Drive Thyroid Tumorigenesis through ATF4 and c-MYC.,Cancer discovery Vol.9, 2019
    La Rocca, Francesco; Airoldi, Irma; Di Carlo, Emma; Marotta, Pina; Falco, Geppino; Simeon, Vittorio; Laurenzana, Ilaria; Trino, Stefania; De Luca, Luciana; Todoerti, Katia; Villani, Oreste; Lackmann, Martin; DAuria, Fiorella; Frassoni, Francesco; Neri, Antonino; Del Vecchio, Luigi; Musto, Pellegrino; Cilloni, Daniela; Caivano, Antonella;,EphA3 targeting reduces in vitro adhesion and invasion and in vivo growth and angiogenesis of multiple myeloma cells.,Cellular oncology (Dordrecht) Vol.40, 2017
    Lapenta, Caterina; Donati, Simona; Spadaro, Francesca; Lattanzi, Laura; Urbani, Francesca; Macchia, Iole; Sestili, Paola; Spada, Massimo; Cox, Maria Christina; Belardelli, Filippo; Santini, Stefano M,Lenalidomide improves the therapeutic effect of an interferon-α-dendritic cell-based lymphoma vaccine.,Cancer immunology, immunotherapy : CII Vol.68, 2019
    Novoplansky, Ofra; Fury, Matthew; Prasad, Manu; Yegodayev, Ksenia; Zorea, Jonathan; Cohen, Limor; Pelossof, Raphael; Cohen, Liz; Katabi, Nora; Cecchi, Fabiola; Joshua, Ben-Zion; Popovtzer, Aron; Baselga, Jose; Scaltriti, Maurizio; Elkabets, Moshe;,MET activation confers resistance to cetuximab, and prevents HER2 and HER3 upregulation in head and neck cancer,International journal of cancer Vol.145, 2019
    Otto, Marius; Blatt, Sebastian; Pabst, Andreas; Mandic, Robert; Schwarz, Johanna; Neff, Andreas; Ziebart, Thomas;,Influence of buffy coat-derived putative endothelial progenitor cells on tumor growth and neovascularization in oral squamous cell carcinoma xenografts.,Clinical oral investigations Vol.23, 2019
    Parvin, Salma; Ramirez-Labrada, Ariel; Aumann, Shlomzion; Lu, XiaoQing; Weich, Natalia; Santiago, Gabriel; Cortizas, Elena M; Sharabi, Eden; Zhang, Yu; Sanchez-Garcia, Isidro; Gentles, Andrew J; Roberts, Evan; Bilbao-Cortes, Daniel; Vega, Francisco; Chapman, Jennifer R; Verdun, Ramiro E; Lossos, Izidore S;,MO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL,Cancer cell Vol.36, 2019
    Punzi, Simona; Balestrieri, Chiara; DAlesio, Carolina; Bossi, Daniela; Dellino, Gaetano Ivan; Gatti, Elena; Pruneri, Giancarlo; Criscitiello, Carmen; Lovati, Giulia; Meliksetyan, Marine; Carugo, Alessandro; Curigliano, Giuseppe; Natoli, Gioacchino; Pelicci, Pier Giuseppe; Lanfrancone, Luisa;,WDR5 inhibition halts metastasis dissemination by repressing the mesenchymal phenotype of breast cancer cells.,Breast cancer research : BCR Vol.21, 2019
    Santoro, Angela; Vlachou, Thalia; Luzi, Lucilla; Melloni, Giorgio; Mazzarella, Luca; DElia, Errico; Aobuli, Xieraili; Pasi, Cristina Elisabetta; Reavie, Linsey; Bonetti, Paola; Punzi, Simona; Casoli, Lucia; Sabò, Arianna; Moroni, Maria Cristina; Dellino, Gaetano Ivan; Amati, Bruno; Nicassio, Francesco; Lanfrancone, Luisa; Pelicci, Pier Giuseppe;,p53 Loss in Breast Cancer Leads to Myc Activation, Increased Cell Plasticity, and Expression of a Mitotic Signature with Prognostic Value,Cell reports Vol.26, 2019
    Sharma, Sambad; Wu, Shih-Ying; Jimenez, Hugo; Xing, Fei; Zhu, Dongqin; Liu, Yin; Wu, Kerui; Tyagi, Abhishek; Zhao, Dan; Lo, Hui-Wen; Metheny-Barlow, Linda; Sun, Peiqing; Bourland, John D; Chan, Michael D; Thomas, Alexandra; Barbault, Alexandre; DAgostino, Ralph B; Whitlow, Christopher T; Kirchner, Volker; Blackman, Carl; Pasche, Boris; Watabe, Kounosuke;,Ca2+ and CACNA1H mediate targeted suppression of breast cancer brain metastasis by AM RF EMF.,EBioMedicine Vol.44, 2019
    Sionov, Ronit Vogt; Fainsod-Levi, Tanya; Zelter, Tamir; Polyansky, Lola; Pham, Christine T; Granot, Zvi;,Neutrophil Cathepsin G and Tumor Cell RAGE Facilitate Neutrophil Anti-Tumor Cytotoxicity.,Oncoimmunology Vol.8, 2019
    Smith BD, Kaufman MD, Lu WP, Gupta A, Leary CB, Wise SC, Rutkoski TJ, Ahn YM, Al-Ani G, Bulfer SL, Caldwell TM, Chun L, Ensinger CL, Hood MM, McKinley A, Patt WC, Ruiz-Soto R, Su Y, Telikepalli H, Town A, Turner BA, Vogeti L, Vogeti S, Yates K, Janku F, Abdul Razak AR, Rosen O, Heinrich MC, Flynn DL.,Ripretinib (DCC-2618) Is a Switch Control Kinase Inhibitor of a Broad Spectrum of Oncogenic and Drug-Resistant KIT and PDGFRA Variants.,Cancer Cell. 2019 May 13;35(5):738-751.e9
    Spriano, Filippo; Tarantelli, Chiara; Gaudio, Eugenio; Gerlach, Magdalena M; Priebe, Valdemar; Cascione, Luciano; Bernasconi, Elena; Targa, Altea; Mascia, Michele; Dirnhofer, Stefan; Stathis, Anastasios; Zucca, Emanuele; Bertoni, Francesco;,Single and combined BTK and PI3Kδ inhibition with acalabrutinib and ACP-319 in pre-clinical models of aggressive lymphomas.,British journal of haematology Vol.187, 2019

    Immunology

    Gunasekaran, K., Pentony, M., Shen, M., Garrett, L., Forte, C., Woodward, A., . . . Yan, W. (2010).,Enhancing antibody fc heterodimer formation through electrostatic steering effects: Applications to bispecific molecules and monovalent IgG,The Journal of Biological Chemistry, 285(25), 19637-19646. doi:10.1074/jbc.M110.117382 [doi]
    Lin, G. H. Y., Chai, V., Lee, V., Dodge, K., Truong, T., Wong, M., . . . Viller, N. N. (2017).,TTI-621 (SIRPalphaFc), a CD47-blocking cancer immunotherapeutic, triggers phagocytosis of lymphoma cells by multiple polarized macrophage subsets,PloS One, 12(10), e0187262. doi:10.1371/journal.pone.0187262 [doi]
    Melis, M. H., Simpson, K. L., Dovedi, S. J., Welman, A., MacFarlane, M., Dive, C., . . . Illidge, T. M. (2013).,Sustained tumour eradication after induced caspase-3 activation and synchronous tumour apoptosis requires an intact host immune response,Cell Death and Differentiation, 20(5), 765-773. doi:10.1038/cdd.2013.8 [doi]
    Oberst, M. D., Auge, C., Morris, C., Kentner, S., Mulgrew, K., McGlinchey, K., . . . Hammond, S. A. (2018).,Potent immune modulation by MEDI6383, an engineered human OX40 ligand IgG4P fc fusion protein.,Molecular Cancer Therapeutics, 17(5), 1024-1038. doi:10.1158/1535-7163.MCT-17-0200 [doi]
    Precechtelova, J., Borsanyiova, M., Stipalova, D., Sarmirova, S., Gomolcak, P., Berakova, K., & Bopegamage, S. (2015).,Pathophysiology of the pancreas after oral infection of genetically diverse mice with coxsackievirus B4-E2,Archives of Virology, 160(1), 103-115. doi:10.1007/s00705-014-2236-7 [doi]
    Reuter, J. D., Fang, X., Ly, C. S., Suter, K. K., & Gibbs, D. (2012),Assessment of hazard risk associated with the intravenous use of viral vectors in rodents,Comparative Medicine, 62(5), 361-370.
    Wooddell, C. I., Rozema, D. B., Hossbach, M., John, M., Hamilton, H. L., Chu, Q., . . . Lewis, D. L. (2013).,Hepatocyte-targeted RNAi therapeutics for the treatment of chronic hepatitis B virus infection.,Molecular Therapy : The Journal of the American Society of Gene Therapy, 21(5), 973-985. doi:10.1038/mt.2013.31 [doi]

    Transplantation

    Argyros, O., Wong, S. P., Gowers, K., & Harbottle, R. P. (2012).,Genetic modification of cancer cells using non-viral, episomal S/MAR vectors for in vivo tumour modelling.,PloS One, 7(10), e47920. doi:10.1371/journal.pone.0047920 [doi]
    Banerjee, K., Pru, C., Pru, J. K., & Resat, H. (2018).,TAT3 knockdown induces tumor formation by MDA-MB-231 cells,Clinical Oncology and Research, 1(1) doi:10.31487/j.COR.2018.10.002 [doi]
    Buzhor, E., Omer, D., Harari-Steinberg, O., Dotan, Z., Vax, E., Pri-Chen, S., . . . Dekel, B. (2013).,Reactivation of NCAM1 defines a subpopulation of human adult kidney epithelial cells with clonogenic and stem/progenitor properties,The American Journal of Pathology, 183(5), 1621-1633. doi:10.1016/j.ajpath.2013.07.034 [doi]
    Calles, A., Rubio-Viqueira, B., & Hidalgo, M. (2013).,Primary human non-small cell lung and pancreatic tumorgraft models--utility and applications in drug discovery and tumor biology.,Current Protocols in Pharmacology / Editorial Board, S.J.Enna (Editor-in-Chief) ...[Et Al.], Chapter 14, Unit 14.26. doi:10.1002/0471141755.ph1426s61 [doi]
    Chartier, C., Raval, J., Axelrod, F., Bond, C., Cain, J., Dee-Hoskins, C., . . . Gurney, A. (2016),Therapeutic targeting of tumor-derived R-spondin attenuates beta-catenin signaling and tumorigenesis in multiple cancer types,Cancer Research, 76(3), 713-723. doi:10.1158/0008-5472.CAN-15-0561 [doi]
    Feys, L., Descamps, B., Vanhove, C., Vermeulen, S., Vandesompele, J. O., Vanderheyden, K., . . . De Wever, O. (2016),Quantitative and functional requirements for bioluminescent cancer models.,In Vivo (Athens, Greece), 30(1), 1-11. doi:30/1/1 [pii]
    Govaere, O., Wouters, J., Petz, M., Vandewynckel, Y. P., Van den Eynde, K., Van den Broeck, A., . . . Roskams, T. (2016).,Laminin-332 sustains chemoresistance and quiescence as part of the human hepatic cancer stem cell niche.,Journal of Hepatology, 64(3), 609-617. doi:10.1016/j.jhep.2015.11.011 [doi]
    Hargus, G., Ehrlich, M., Arauzo-Bravo, M. J., Hemmer, K., Hallmann, A. L., Reinhardt, P., . . . Zaehres, H. (2014).,Origin-dependent neural cell identities in differentiated human iPSCs in vitro and after transplantation into the mouse brain,Cell Reports, 8(6), 1697-1703. doi:10.1016/j.celrep.2014.08.014 [doi]
    Lima, M. J., Muir, K. R., Docherty, H. M., Drummond, R., McGowan, N. W., Forbes, S., . . . Docherty, K. (2013),Suppression of epithelial-to-mesenchymal transitioning enhances ex vivo reprogramming of human exocrine pancreatic tissue toward functional insulin-producing beta-like cells.,Diabetes, 62(8), 2821-2833. doi:10.2337/db12-1256 [doi]
    Loebinger, M. R., Kyrtatos, P. G., Turmaine, M., Price, A. N., Pankhurst, Q., Lythgoe, M. F., & Janes, S. M. (2009).,Magnetic resonance imaging of mesenchymal stem cells homing to pulmonary metastases using biocompatible magnetic nanoparticles.,Cancer Research, 69(23), 8862-8867. doi:10.1158/0008-5472.CAN-09-1912 [doi]
    Maldonado, A. A., Cristobal, L., Martin-Lopez, J., Mallen, M., Garcia-Honduvilla, N., & Bujan, J. (2014).,A novel model of human skin pressure ulcers in mice.,PloS One, 9(10), e109003. doi:10.1371/journal.pone.0109003 [doi]
    Marin-Ramos, N. I., Thein, T. Z., Cho, H. Y., Swenson, S. D., Wang, W., Schonthal, A. H., . . . Hofman, F. M. (2018),NEO212 inhibits migration and invasion of glioma stem cells.,Molecular Cancer Therapeutics, 17(3), 625-637. doi:10.1158/1535-7163.MCT-17-0591 [doi]
    Milazzo, L., Vulcano, F., Barca, A., Macioce, G., Paldino, E., Rossi, S., . . . Giampaolo, A. (2014).,Cord blood CD34+ cells expanded on wharton's jelly multipotent mesenchymal stromal cells improve the hematopoietic engraftment in NOD/SCID mice,European Journal of Haematology, 93(5), 384-391. doi:10.1111/ejh.12363 [doi]
    Owonikoko, T. K., Zhang, G., Kim, H. S., Stinson, R. M., Bechara, R., Zhang, C., . . . Khuri, F. R. (2016).,Patient-derived xenografts faithfully replicated clinical outcome in a phase II co-clinical trial of arsenic trioxide in relapsed small cell lung cancer,Journal of Translational Medicine, 14(1), 111-016-0861-5. doi:10.1186/s12967-016-0861-5 [doi]
    Peled, T., Shoham, H., Aschengrau, D., Yackoubov, D., Frei, G., Rosenheimer, G. N., . . . Peled, A. (2012),Nicotinamide, a SIRT1 inhibitor, inhibits differentiation and facilitates expansion of hematopoietic progenitor cells with enhanced bone marrow homing and engraftment,Experimental Hematology, 40(4), 342-55.e1. doi:10.1016/j.exphem.2011.12.005 [doi]
    Petrillo, L. A., Wolf, D. M., Kapoun, A. M., Wang, N. J., Barczak, A., Xiao, Y., . . . Esserman, L. J. (2012).,Xenografts faithfully recapitulate breast cancer-specific gene expression patterns of parent primary breast tumors,Breast Cancer Research and Treatment, 135(3), 913-922. doi:10.1007/s10549-012-2226-y [doi]
    Rauner, G., & Barash, I. (2014),Xanthosine administration does not affect the proportion of epithelial stem cells in bovine mammary tissue, but has a latent negative effect on cell proliferation.,Experimental Cell Research, 328(1), 186-196. doi:10.1016/j.yexcr.2014.06.017 [doi]
    Thomson, A. J., Pierart, H., Meek, S., Bogerman, A., Sutherland, L., Murray, H., . . . Burdon, T. (2012).,Reprogramming pig fetal fibroblasts reveals a functional LIF signaling pathway,Cellular Reprogramming, 14(2), 112-122. doi:10.1089/cell.2011.0078 [doi]
    Vulcano, F., Milazzo, L., Ciccarelli, C., Barca, A., Agostini, F., Altieri, I., . . . Hassan, H. J. (2012).,Valproic acid affects the engraftment of TPO-expanded cord blood cells in NOD/SCID mice.,Experimental Cell Research, 318(4), 400-407. doi:10.1016/j.yexcr.2011.11.012 [doi]
    Wang, L., Rahman, S., Lin, C. Y., Valdivia, J., Than, K., La Marca, F., & Park, P. (2012).,A novel murine model of human renal cell carcinoma spinal metastasis.,Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia, 19(6), 881-883. doi:10.1016/j.jocn.2011.10.019 [doi]
    Westenfelder, C., Gooch, A., Hu, Z., Ahlstrom, J., & Zhang, P. (2017).,Durable control of autoimmune diabetes in mice achieved by intraperitoneal transplantation of "neo-islets," three-dimensional aggregates of allogeneic islet and "mesenchymal stem cells",Stem Cells Translational Medicine, 6(7), 1631-1643. doi:10.1002/sctm.17-0005 [doi]
    Yuan, X., Wei, Y., Villasante, A., Ng, J. J. D., Arkonac, D. E., Chao, P. G., & Vunjak-Novakovic, G. (2017).,Stem cell delivery in tissue-specific hydrogel enabled meniscal repair in an orthotopic rat model,Biomaterials, 132, 59-71. doi:S0142-9612(17)30213-2 [pii]
    Zhang, Y., Zheng, D., Zhou, T., Song, H., Hulsurkar, M., Su, N., . . . Li, W. (2018).,Androgen deprivation promotes neuroendocrine differentiation and angiogenesis through CREB-EZH2-TSP1 pathway in prostate cancers.,Nature Communications, 9(1), 4080-018-06177-2. doi:10.1038/s41467-018-06177-2 [doi]
    Cristóbal, Lara; de Los Reyes, Nerea; Ortega, Miguel A; Álvarez-Mon, Melchor; García-Honduvilla, Natalio; Buján, Julia; Maldonado, Andrés A;,Local Growth Hormone Therapy for Pressure Ulcer Healing on a Human Skin Mouse Model,International journal of molecular sciences Vol.20, 2019
    Elovic, Edan; Etzion, Sharon; Cohen, Smadar;,MiR-499 Responsive Lethal Construct for Removal of Human Embryonic Stem Cells after Cardiac Differentiation,Scientific reports Vol.9, 2019

    Tumor Cell Growth

    Achyut, B. R., Shankar, A., Iskander, A. S., Ara, R., Knight, R. A., Scicli, A. G., & Arbab, A. S. (2016).,Chimeric mouse model to track the migration of bone marrow derived cells in glioblastoma following anti-angiogenic treatments,Cancer Biology & Therapy, 17(3), 280-290. doi:10.1080/15384047.2016.1139243 [doi]
    Andretta, E., Carton-Garcia, F., Martinez-Barriocanal, A., de Marcondes, P. G., Jimenez-Flores, L. M., Macaya, I., . . . Arango, D. (2017).,Investigation of the role of tyrosine kinase receptor EPHA3 in colorectal cancer.,Scientific Reports, 7, 41576. doi:10.1038/srep41576 [doi]
    Bellavia, D., Raimondo, S., Calabrese, G., Forte, S., Cristaldi, M., Patinella, A., . . . Alessandro, R. (2017).,Interleukin 3- receptor targeted exosomes inhibit in vitro and in vivo chronic myelogenous leukemia cell growth,Theranostics, 7(5), 1333-1345. doi:10.7150/thno.17092 [doi]
    Boesch, M., Zeimet, A. G., Reimer, D., Schmidt, S., Gastl, G., Parson, W., . . . Sopper, S. (2014).,The side population of ovarian cancer cells defines a heterogeneous compartment exhibiting stem cell characteristics.,Oncotarget, 5(16), 7027-7039. doi:2053 [pii]
    Carrascosa, C., Obula, R. G., Missiaglia, E., Lehr, H. A., Delorenzi, M., Frattini, M., . . . Mariotti, A. (2012).,MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells.,Oncogene, 31(12), 1521-1532. doi:10.1038/onc.2011.356 [doi]
    Dattilo, V., D'Antona, L., Talarico, C., Capula, M., Catalogna, G., Iuliano, R., . . . Amato, R. (2017).,SGK1 affects RAN/RANBP1/RANGAP1 via SP1 to play a critical role in pre-miRNA nuclear export: A new route of epigenomic regulation,Scientific Reports, 7, 45361. doi:10.1038/srep45361 [doi]
    Desiderio, V., Papagerakis, P., Tirino, V., Zheng, L., Matossian, M., Prince, M. E., . . . Papagerakis, S. (2015).,Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells.,Oncotarget, 6(1), 71-84. doi:2698 [pii]
    Desiderio, V., Papagerakis, P., Tirino, V., Zheng, L., Matossian, M., Prince, M. E., . . . Papagerakis, S. (2015).,Increased fucosylation has a pivotal role in invasive and metastatic properties of head and neck cancer stem cells.,Oncotarget, 6(1), 71-84. doi:2698 [pii]
    Dvorkina, M., Nieddu, V., Chakelam, S., Pezzolo, A., Cantilena, S., Leite, A. P., . . . Salomoni, P. (2016),A promyelocytic leukemia protein-thrombospondin-2 axis and the risk of relapse in neuroblastoma,Clinical Cancer Research : An Official Journal of the American Association for Cancer Research, 22(13), 3398-3409. doi:10.1158/1078-0432.CCR-15-2081 [doi]
    Escobar-Hoyos, L. F., Shah, R., Roa-Pena, L., Vanner, E. A., Najafian, N., Banach, A., . . . Shroyer, K. R. (2015),Keratin-17 promotes p27KIP1 nuclear export and degradation and offers potential prognostic utility.,Cancer Research, 75(17), 3650-3662. doi:10.1158/0008-5472.CAN-15-0293 [doi]
    Escobar-Hoyos, L. F., Shah, R., Roa-Pena, L., Vanner, E. A., Najafian, N., Banach, A., . . . Shroyer, K. R. (2015),Keratin-17 promotes p27KIP1 nuclear export and degradation and offers potential prognostic utility.,Cancer Research, 75(17), 3650-3662. doi:10.1158/0008-5472.CAN-15-0293 [doi]
    Fareh, M., Almairac, F., Turchi, L., Burel-Vandenbos, F., Paquis, P., Fontaine, D., . . . Virolle, T. (2017).,Cell-based therapy using miR-302-367 expressing cells represses glioblastoma growth,Cell Death & Disease, 8(3), e2713. doi:10.1038/cddis.2017.117 [doi]
    Fareh, M., Turchi, L., Virolle, V., Debruyne, D., Almairac, F., de-la-Forest Divonne, S., . . . Virolle, T. (2012).,The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network,Cell Death and Differentiation, 19(2), 232-244. doi:10.1038/cdd.2011.89 [doi]
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