General Studies

    Comer, Jason E; Ray, Bryan D; Henning, Lisa N; Stark, Gregory V; Barnewall, Roy E; Mott, Jason M; Meister, Gabriel T;, Characterization of a therapeutic model of inhalational anthrax using an increase in body temperature in New Zealand white rabbits as a trigger for treatment. Clinical and vaccine immunology, CVI Vol.19, 2012
    Oscherwitz J, Feldman D, Yu F, Cease KB., Epitope-focused peptide immunogens in human use adjuvants protect rabbits from experimental inhalation anthrax., Vaccine. 2015 Jan 9;33(3):430-6.
    Posobiec LM, Cox EM, Solomon HM, Lewis EM, Wang KF, Stanislaus D, A Probability Analysis of Historical Pregnancy and Fetal Data from Dutch Belted and New Zealand White Rabbit Strains from Embryo-Fetal Development Studies., Birth Defects Res B Dev Reprod Toxicol. 2016 Apr;107(2):76-84


    Hawksworth D., Advancing Freund's and AddaVax Adjuvant Regimens Using CpG Oligodeoxynucleotides., Monoclon Antib Immunodiagn Immunother. 2018 Nov;37(5):195-199.
    Houser KV, Broadbent AJ, Gretebeck L, Vogel L, Lamirande EW, Sutton T, Bock KW, Minai M, Orandle M, Moore IN, Subbarao K., Enhanced inflammation in New Zealand white rabbits when MERS-CoV reinfection occurs in the absence of neutralizing antibody., PLoS Pathog. 2017 Aug 17;13(8):e1006565.
    Panda, Aruna; Tatarov, Ivan; Melton-Celsa, Angela R; Kolappaswamy, Krishnan; Kriel, Edwin H; Petkov, Daniel; Coksaygan, Turhan; Livio, Sofie; McLeod, Charles G; Nataro, James P; OBrien, Alison D; DeTolla, Louis J;, Escherichia coli O157:H7 infection in Dutch belted and New Zealand white rabbits, Comparative medicine Vol.60, 2010
    Reed MD, Wilder JA, Mega WM, Hutt JA, Kuehl PJ, Valderas MW, Chew LL, Liang BC, Squires CH, Immunization with a Recombinant, Pseudomonas fluorescens-Expressed, Mutant Form of Bacillus anthracis-Derived Protective Antigen Protects Rabbits from Anthrax Infection., PLoS One. 2015 Jul 24;10(7):e0130952.
    Townsley S, Mohamed Z, Guo W, McKenna J, Cleveland B, LaBranche C, Beaumont D, Shen X, Yates NL, Pinter A, Tomaras GD, Ferrari G, Montefiori DC, Hu SL., Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization., J Virol. 2016 Sep 12;90(19):8644-60.
    Yamane K, Leung KP., Rabbit M1 and M2 macrophages can be induced by human recombinant GM-CSF and M-CSF., FEBS Open Bio. 2016 Aug 15;6(9):945-53.


    Chollet, Janet; Mermelstein, Fred; Rocamboli, Stephen C; Friend, David R;, Vaginal tamoxifen for treatment of vulvar and vaginal atrophy: Pharmacokinetics and local tolerance in a rabbit model over 28 days., International journal of pharmaceutics Vol.570, 2019
    Coursey, Terry G; Wassel, Ronald A; Quiambao, Alexander B; Farjo, Rafal A;, Once-Daily Cyclosporine-A-MiDROPS for Treatment of Dry Eye Disease., Translational vision science & technology Vol.7, 2018
    Grossi, Irma M; Foster, Scott A; Gainey, Melicia R; Krile, Robert T; Dunn, John A; Brundage, Thomas; Khouri, Jody M;, Efficacy of delayed brincidofovir treatment against a lethal rabbitpox virus challenge in New Zealand White rabbits., Antiviral research Vol.143, 2017
    Gutting, Bradford W; Nichols, Tonya L; Channel, Stephen R; Gearhart, Jeffery M; Andrews, George A; Berger, Alan E; Mackie, Ryan S; Watson, Brent J; Taft, Sarah C; Overheim, Katie A; Sherwood, Robert L;, Inhalational anthrax (Ames aerosol) in naïve and vaccinated New Zealand rabbits: characterizing the spread of bacteria from lung deposition to bacteremia, Frontiers in cellular and infection microbiology Vol.2, 2012
    Hild, S A; Reel, J R; Hoffman, L H; Blye, R P;, CDB-2914: anti-progestational/anti-glucocorticoid profile and post-coital anti-fertility activity in rats and rabbits, Human reproduction (Oxford, England) Vol.15, 2000
    Ibarra, R; Dazard, J-E; Sandlers, Y; Rehman, F; Abbas, R; Kombu, R; Zhang, G-F; Brunengraber, H; Sanabria, J;, Metabolomic Analysis of Liver Tissue from the VX2 Rabbit Model of Secondary Liver Tumors., HPB surgery : a world journal of hepatic, pancreatic and biliary surgery Vol.2014, 2014
    Iyer, Ganesh R; Cason, Marita M; Womble, Scott W; Li, Guangming; Chastain, James E;, Ocular pharmacokinetics comparison between 0.2% olopatadine and 0.77% olopatadine hydrochloride ophthalmic solutions administered to male New Zealand white rabbits., ournal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.31, 2015
    Kammanadiminti, Srinivas; Patnaikuni, Ravi Kumar; Comer, Jason; Meister, Gabriel; Sinclair, Chris; Kodihalli, Shantha;, Combination therapy with antibiotics and anthrax immune globulin intravenous (AIGIV) is potentially more effective than antibiotics alone in rabbit model of inhalational anthrax., PloS one Vol.9, 2014
    Kim, Kyong Ho; Cao, Jiafu; Yoo, Jin-Wook; Yoon, In-Soo; Jung, Jae Woo; Lee, Ji Eun; Byon, Ik Soo;, Intraocular Pharmacokinetics of Povidone-Iodine and Its Effects on Experimental Staphylococcus epidermidis Endophthalmitis, Investigative ophthalmology & visual science Vol.56, 2015
    Nagy, C F; Mondick, J; Serbina, N; Casey, L S; Carpenter, S E; French, J; Guttendorf, R;, Animal-to-Human Dose Translation of Obiltoxaximab for Treatment of Inhalational Anthrax Under the US FDA Animal Rule., Clinical and translational science Vol.10, 2017
    Perry, Mark R; Warren, Richard; Merchlinsky, Michael; Houchens, Christopher; Rogers, James V;, Rabbitpox in New Zealand White Rabbits: A Therapeutic Model for Evaluation of Poxvirus Medical Countermeasures Under the FDA Animal Rule, Frontiers in cellular and infection microbiology Vol.8, 2018
    Petraitis, Vidmantas; Petraitiene, Ruta; Maung, Bo Bo W; Khan, Farehin; Alisauskaite, Ieva; Olesky, Melanie; Newman, Joseph; Mutlib, Abdul; Niu, Xiaoyun; Satlin, Michael; Singh, Ravi S; Derendorf, Harmut; Walsh, Thomas J;, Pharmacokinetics and Comprehensive Analysis of the Tissue Distribution of Eravacycline in Rabbits, Antimicrobial agents and chemotherapy Vol.62, 2018
    Petraitis, Vidmantas; Petraitiene, Ruta; Naing, Ethan; Aung, Thein; Thi, Wai Phyo; Kavaliauskas, Povilas; Win Maung, Bo Bo; Michel, Adam O; Ricart Arbona, Rodolfo J; DeRyke, Andrew C; Culshaw, Darren L; Nicolau, David P; Satlin, Michael J; Walsh, Thomas J;, Ceftolozane-Tazobactam in the Treatment of Experimental Pseudomonas aeruginosa Pneumonia in Persistently Neutropenic Rabbits: Impact on Strains with Genetically Defined Mechanisms of Resistance., Antimicrobial agents and chemotherapy Vol.63, 2019
    Schoenberg, Evan D; Blake, Diane A; Swann, F Beau; Parlin, Andrew W; Zurakowski, David; Margo, Curtis E; Ponnusamy, Thiruselvam; John, Vijay T; Ayyala, Ramesh S;, Effect of Two Novel Sustained-Release Drug Delivery Systems on Bleb Fibrosis: An In Vivo Glaucoma Drainage Device Study in a Rabbit Model., Translational vision science & technology Vol.4, 2015
    Schopf, Lisa R; Popov, Alexey M; Enlow, Elizabeth M; Bourassa, James L; Ong, Winston Z; Nowak, Pawel; Chen, Hongming;, Topical Ocular Drug Delivery to the Back of the Eye by Mucus-Penetrating Particles., Translational vision science & technology Vol.4, 2015
    Shen, Jie; Goodkin, Margot L; Tong, Warren; Attar, Mayssa;, Ocular pharmacokinetics and tolerability of bimatoprost ophthalmic solutions administered once or twice daily in rabbits, and clinical dosing implications., Clinical ophthalmology (Auckland, N.Z.) Vol.11, 2017
    Trost, Lawrence C; Rose, Michelle L; Khouri, Jody; Keilholz, Laurie; Long, James; Godin, Stephen J; Foster, Scott A;, The efficacy and pharmacokinetics of brincidofovir for the treatment of lethal rabbitpox virus infection: a model of smallpox disease., Antiviral research Vol.117, 2015
    Verhoeven, Rozemarijn S; Garcia, Andres; Robeson, RiLee; Gilger, Brian C; Culp, David; Struble, Craig; Hamm, Lee; Navratil, Tomas; Yerxa, Benjamin;, Nonclinical Development of ENV905 (Difluprednate) Ophthalmic Implant for the Treatment of Inflammation and Pain Associated with Ocular Surgery., Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.34,
    Wink, Jason D; Gerety, Patrick A; Sherif, Rami D; Lim, Youngshin; Clarke, Nadya A; Rajapakse, Chamith S; Nah, Hyun-Duck; Taylor, Jesse A, Sustained delivery of rhBMP-2 by means of poly(lactic-co-glycolic acid) microspheres: cranial bone regeneration without heterotopic ossification or craniosynostosis., Plastic and reconstructive surgery Vol.134, 2014
    Yamamoto, Brent J; Shadiack, Annette M; Carpenter, Sarah; Sanford, Daniel; Henning, Lisa N; Gonzales, Nestor; OConnor, Edward; Casey, Leslie S; Serbina, Natalya V;, Obiltoxaximab Prevents Disseminated Bacillus anthracis Infection and Improves Survival during Pre- and Postexposure Prophylaxis in Animal Models of Inhalational Anthrax., Antimicrobial agents and chemotherapy Vol.60, 2016
    Yamamoto, Brent J; Shadiack, Annette M; Carpenter, Sarah; Sanford, Daniel; Henning, Lisa N; OConnor, Edward; Gonzales, Nestor; Mondick, John; French, Jonathan; Stark, Gregory V; Fisher, Alan C; Casey, Leslie S; Serbina, Natalya V, Efficacy Projection of Obiltoxaximab for Treatment of Inhalational Anthrax across a Range of Disease Severity., Antimicrobial agents and chemotherapy Vol.60, 2016


    Breslin WJ, Hilbish KG, Martin JA, Halstead CA, Edwards TL., Developmental Toxicity and Fertility Assessment in Rabbits with Tabalumab: A Human IgG4 Monoclonal Antibody, . Birth Defects Res B Dev Reprod Toxicol. 2015 Jun;104(3):117-28
    Campion SN, Davenport SJ, Nowland WS, Cappon GD, Bowman CJ, Hurtt ME, Sensitive windows of skeletal development in rabbits determined by hydroxyurea exposure at different times throughout gestation, Birth Defects Res B Dev Reprod Toxicol. 2012 Jun;95(3):238-49.
    Catlin NR, Bowman CJ, Engel SM, Sacaan A, Thibault S, Lewis EM, Cappon GD., Reproductive and developmental toxicity assessment of palbociclib, a CDK4/6 inhibitor, in Sprague-Dawley rats and New Zealand White rabbits., Reprod Toxicol. 2019 Sep;88:76-84.
    Catlin N, Waidyanatha S, Mylchreest E, Miller-Pinsler L, Cunny H, Foster P, Sutherland V, McIntyre B., Embryo-fetal development studies with the dietary supplement vinpocetine in the rat and rabbit., Birth Defects Res. 2018 Jun 1;110(10):883-896
    Hilbish KG, Martin JA, Stauber AJ, Edwards TL, Breslin WJ., Assessment of embryo-fetal toxicity in rats and rabbits., Birth Defects Res B Dev Reprod Toxicol. 2016 Aug;107(4-5):174-184
    Keswani SG, Balaji S, Katz AB, King A, Omar K, Habli M, Klanke C, Crombleholme TM., Intraplacental gene therapy with Ad-IGF-1 corrects naturally occurring rabbit model of intrauterine growth restriction., Hum Gene Ther. 2015 Mar;26(3):172-82.
    Marshall VA, Johnson KJ, Moore NP, Rasoulpour RJ, Tornesi B, Carney EW., Comparative response of rat and rabbit conceptuses in vitro to inhibitors of histiotrophic nutrition, Birth Defects Res B Dev Reprod Toxicol. 2015 Feb;104(1):1-10
    Moore NP, Picut CA, Charlap JH., Localisation of Lactate Transporters in Rat and Rabbit Placentae., Int J Cell Biol. 2016;2016:2084252
    Sakurai K, Matsuoka T, Suzuki C, Kinoshita J, Takayama G, Shimomura K., Investigation of the teratogenic potential of VLA-4 antagonist derivatives in rats, Reprod Toxicol. 2014 Nov;49:162-70.


    Chandra SA, Peterson RA, Melich D, Merrill CM, Bailey D, Mellon-Kusibab K, Adler R., Dermal irritation of petrolatum in rabbits but not in mice, rats or minipigs., J Appl Toxicol. 2014 Aug;34(8):857-61.
    Chapman JR, Moore K, Butterworth BE., Pathogen inactivation of RBCs: PEN110 reproductive toxicology studies, Transfusion. 2003 Oct;43(10):1386-93.
    Fichorova RN, Mendonca K, Yamamoto HS, Murray R, Chandra N, Doncel GF, A quantitative multiplex nuclease protection assay reveals immunotoxicity gene expression profiles in the rabbit model for vaginal drug safety evaluation., Toxicol Appl Pharmacol. 2015 Jun 15;285(3):198-206.
    Fouladi N, Parker M, Kennedy V, Binley K, McCloskey L, Loader J, Kelleher M, Mitrophanous KA, Stout JT, Ellis S., Safety and Efficacy of OXB-202, a Genetically Engineered Tissue Therapy for the Prevention of Rejection in High-Risk Corneal Transplant Patients, Hum Gene Ther. 2018 Jun;29(6):687-698
    HogenEsch H, Dunham A, Burlet E, Lu F, Mosley YC, Morefield G., Preclinical safety study of a recombinant Streptococcus pyogenes vaccine formulated with aluminum adjuvant., J Appl Toxicol. 2017 Feb;37(2):222-230.
    Ramot Y, Nedvetzki S, Rosenfeld S, Emanuel N, Nyska A., Toxicity and Safety Study of D-PLEX100 in a Sternal Surgical Defect in New Zealand White Rabbits, Toxicol Pathol. 2019 Jun;47(4):504-514.
    Tveit A, Rusch GM, Muijser H, van den Hoven MJ, Hoffman GM., The acute, genetic, developmental and inhalation toxicology of trans-1-chloro,3,3,3-trifluoropropene (HCFO-1233zd(E))., Drug Chem Toxicol. 2014 Jan;37(1):83-92.