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    ADMET

    Fuchs, Holger; Kishimoto, Wataru; Gansser, Dietmar; Tanswell, Paul; Ishiguro, Naoki;, Brain penetration of WEB 2086 (Apafant) and dantrolene in Mdr1a (P-glycoprotein) and Bcrp knockout rats., Drug metabolism and disposition: the biological fate of chemicals Vol.42, 2014
    Suzuki, Motoya; Komura, Hiroshi; Yoshikawa, Tomonori; Enya, Seiji; Nagao, Akemi; Takubo, Hiroaki; Kogayu, Motohiro;, Characterization of gastrointestinal absorption of digoxin involving influx and efflux transporter in rats: application of mdr1a knockout (-/-) rats into absorption study of multiple transporter substrate., Xenobiotica; the fate of foreign compounds in biological systems Vol.44, 2014
    Zamek-Gliszczynski, Maciej J; Bedwell, David W; Bao, Jing Q; Higgins, J William;, Characterization of SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats using loperamide, paclitaxel, sulfasalazine, and carboxydichlorofluorescein pharmacokinetics., Drug metabolism and disposition: the biological fate of chemicals Vol.40, 2012
    Huang, Liyue; Li, Xingwen; Roberts, Jonathan; Janosky, Brett; Lin, Min-Hwa Jasmine;, Differential role of P-glycoprotein and breast cancer resistance protein in drug distribution into brain, CSF and peripheral nerve tissues in rats., Xenobiotica; the fate of foreign compounds in biological systems Vol.45, 2015
    Fujii, Shinobu; Setoguchi, Chikako; Kawazu, Kouichi; Hosoya, Ken-ichi;, Functional Characterization of Carrier-Mediated Transport of Pravastatin across the Blood-Retinal Barrier in Rats., Drug metabolism and disposition: the biological fate of chemicals Vol.43, 2015
    Fujii, Shinobu; Setoguchi, Chikako; Kawazu, Kouichi; Hosoya, Ken-ichi;, Impact of P-glycoprotein on blood-retinal barrier permeability: comparison of blood-aqueous humor and blood-brain barrier using mdr1a knockout rats., Investigative ophthalmology & visual science Vol.55, 2014
    Dumas, Noé; Moulin-Sallanon, Marcelle; Fender, Pascal; Tournier, Benjamin B; Ginovart, Nathalie; Charnay, Yves; Millet, Philippe;, In Vivo Quantification of 5-HT2A Brain Receptors in Mdr1a KO Rats with 123I-R91150 Single-Photon Emission Computed Tomography., Molecular imaging Vol.14, 2015
    Sato, Sho; Tohyama, Kimio; Kosugi, Yohei;, Investigation of MDR1-overexpressing cell lines to derive a quantitative prediction approach for brain disposition using in vitro efflux activities., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Vol.142, 2020
    Nagaya, Yoko; Nozaki, Yoshitane; Takenaka, Osamu; Watari, Ryuji; Kusano, Kazutomi; Yoshimura, Tsutomu; Kusuhara, Hiroyuki;, Investigation of utility of cerebrospinal fluid drug concentration as a surrogate for interstitial fluid concentration using microdialysis coupled with cisternal cerebrospinal fluid sampling in wild-type and Mdr1a(-/-) rats., Drug metabolism and pharmacokinetics Vol.31, 2016
    Ganguly, Samit; Panetta, John C; Roberts, Jessica K; Schuetz, Erin G;, Ketamine Pharmacokinetics and Pharmacodynamics Are Altered by P-Glycoprotein and Breast Cancer Resistance Protein Efflux Transporters in Mice., Drug metabolism and disposition: the biological fate of chemicals Vol.46, 2018
    Zamek-Gliszczynski, Maciej J; Goldstein, Keith M; Paulman, April; Baker, Thomas K; Ryan, Timothy P;, Minor compensatory changes in SAGE Mdr1a (P-gp), Bcrp, and Mrp2 knockout rats do not detract from their utility in the study of transporter-mediated pharmacokinetics., Drug metabolism and disposition: the biological fate of chemicals Vol.41, 2013
    Al-Ali, Ahmed A Abdulhussein; Quach, Jeffrey Rong Chao; Bundgaard, Christoffer; Steffansen, Bente; Holm, René; Nielsen, Carsten Uhd;, Polysorbate 20 alters the oral bioavailability of etoposide in wild type and mdr1a deficient Sprague-Dawley rats., International journal of pharmaceutics Vol.543, 2018
    Nielsen, Carsten Uhd; Abdulhussein, Ahmed A; Colak, Dilan; Holm, René;, Polysorbate 20 increases oral absorption of digoxin in wild-type Sprague Dawley rats, but not in mdr1a(-/-) Sprague Dawley rats., International journal of pharmaceutics Vol.513, 2016
    Nicolas, Jean-Marie; Chanteux, Hugues; Nicolaï, Johan; Brouta, Frédéric; Viot, Delphine; Rosseels, Marie-Luce; Gillent, Eric; Bonnaillie, Pierre; Mathy, François-Xavier; Long, Jeff; Helmer, Eric;, Role of P-glycoprotein in the brain disposition of seletalisib: Evaluation of the potential for drug-drug interactions., European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences Vol.142, 2020
    Dulin, Jennifer N; Moore, Meredith L; Grill, Raymond J;, The dual cyclooxygenase/5-lipoxygenase inhibitor licofelone attenuates p-glycoprotein-mediated drug resistance in the injured spinal cord., Journal of neurotrauma Vol.30, 2013
    Liu, Xingrong; Cheong, Jonathan; Ding, Xiao; Deshmukh, Gauri;, Use of cassette dosing approach to examine the effects of P-glycoprotein on the brain and cerebrospinal fluid concentrations in wild-type and P-glycoprotein knockout rats., Drug metabolism and disposition: the biological fate of chemicals Vol.42, 2014
    Chiang M, Back HM, Lee JB, Oh S, Guo T, Girgis S, Park C, Haroutounian S, Kagan L., Pharmacokinetic Modeling of the Impact of P-glycoprotein on Ondansetron Disposition in the Central Nervous System, Pharm Res. 2020 Sep 28;37(10):205. doi: 10.1007/s11095-020-02929-2.
    Tsartsalis S, Tournier BB, Millet P., In vivo absolute quantification of striatal and extrastriatal D(2/3) receptors with [(123)I]epidepride SPECT, EJNMMI Res. 2020 Jun 16;10(1):66. doi: 10.1186/s13550-020-00650-0.