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ADMET

Fuchs H, Kishimoto W, Gansser D, Tanswell P, Ishiguro N., Brain penetration of WEB 2086 (Apafant) and dantrolene in Mdr1a (P-glycoprotein) and Bcrp knockout rats., Drug Metab Dispos. 2014 Oct;42(10):1761-5. doi: 10.1124/dmd.114.058545.Epub 2014 Jul 22.
Huang L, Li X, Roberts J, Janosky B, Lin MH., Differential role of P-glycoprotein and breast cancer resistance protein in drug distribution into brain, CSF and peripheral nerve tissues in rats., Xenobiotica. 2015;45(6):547-55. doi: 10.3109/00498254.2014.997324.
Ganguly S, Panetta JC, Roberts JK, Schuetz EG., Ketamine Pharmacokinetics and Pharmacodynamics Are Altered by P-Glycoprotein and Breast Cancer Resistance Protein Efflux Transporters in Mice., Drug Metab Dispos. 2018 Jul;46(7):1014-1022. doi: 10.1124/dmd.117.078360. Epub 2018 Apr 19.

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