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General studies

Posobiec LM, Cox EM, Solomon HM, Lewis EM, Wang KF, Stanislaus D., A Probability Analysis of Historical Pregnancy and Fetal Data from Dutch Belted and New Zealand White Rabbit Strains from Embryo-Fetal Development Studies, Birth Defects Res B Dev Reprod Toxicol. 2016 Apr;107(2):76-84
Al-Nawaiseh S, Krötz C, Rickmann A, Strack C, Germann A, von Briesen H, Szurman P, Schulz A, Stanzel BV., A rabbit model for outer retinal atrophy caused by surgical RPE removal, Graefes Arch Clin Exp Ophthalmol. 2023 Aug;261(8):2265-2280. doi: 10.1007/s00417-023-06014-3. Epub 2023 Mar 28.
Master A, Huang W, Huang L, Honkanen R, Rigas B., An Improved Ocular Impression Cytology Method: Quantitative Cell Transfer to Microscope Slides Using a Novel Polymer, Curr Eye Res. 2022 Jan;47(1):41-50. doi: 10.1080/02713683.2021.1951300. Epub 2021 Nov 27.
Zeng Y, Nguyen VP, Li Y, Kang DH, Paulus YM, Kim J., Chorioretinal Hypoxia Detection Using Lipid-Polymer Hybrid Organic Room-Temperature Phosphorescent Nanoparticles, ACS Appl Mater Interfaces. 2022 Apr 27;14(16):18182-18193. doi: 10.1021/acsami.2c02767. Epub 2022 Apr 14.
Ziejewski MK, Solomon HM, Rendemonti J, Stanislaus D., Comparison of a modified mid-coronal sectioning technique and Wilson's technique when conducting eye and brain examinations in rabbit teratology studies., Birth Defects Res B Dev Reprod Toxicol. 2015 Feb;104(1):23-34
Day ML., Head-related transfer functions of rabbits within the front horizontal plane, Hear Res. 2024 Jan;441:108924. doi: 10.1016/j.heares.2023.108924. Epub 2023 Dec 2.
Hoang, Quan V.; Wen, Quan; Paik, David C.; Chun, Yong Yao; Silverman, Ronald; Nagasaki, Takayuki; Trokel, Stephen L.; Zyablitskaya, Mariya, Scleral growth stunting via sub-Tenon injection of cross-linking solutions in live rabbits, British Journal of Ophthalmology. Published Online First: 20 October 2021
Mitchell PW, Henry KS, Carney LH., Sensitivity to direction and velocity of fast frequency chirps in the inferior colliculus of awake rabbit, Hear Res. 2023 Dec;440:108915. doi: 10.1016/j.heares.2023.108915. Epub 2023 Nov 15.
Parikh BH, Blakeley P, Regha K, Liu Z, Yang B, Bhargava M, Wong DSL, Tan QSW, Wong CSW, Wang HF, Al-Mubaarak A, Chou C, Cheung CMG, Lim KL, Barathi VA, Hunziker W, Lingam G, Hu TX, Su X., Single-cell transcriptomics reveals maturation of transplanted stem cell-derived retinal pigment epithelial cells toward native state, Proc Natl Acad Sci U S A. 2023 Jun 27;120(26):e2214842120. doi: 10.1073/pnas.2214842120. Epub 2023 Jun 20.
Zhou C, Lei F, Sharma J, Hui PC, Wolkow N, Dohlman CH, Vavvas DG, Chodosh J, Paschalis EI., Sustained Inhibition of VEGF and TNF-α Achieves Multi-Ocular Protection and Prevents Formation of Blood Vessels after Severe Ocular Trauma, Pharmaceutics. 2023 Jul 31;15(8):2059. doi: 10.3390/pharmaceutics15082059.
Wozniak, Kaitlin T.; Butler, Sam C.; He, Xu; Ellis, Jonathan D.; Knox, Wayne H.; Huxlin, Krystel R., Temporal evolution of the biological response to laser-induced refractive index change (LIRIC) in rabbit corneas, Experimental Eye Research. Volume 207, June 2021, 108579.
Master, Adam; Kontzias, Apostolos; Huang, Liqun; Huang, Wei; Tsioulias, Anna; Zarabi, Samaneh; Wolek, Michael; Wollocko, Brian M.; Honkanen, Robert; Rigas, Basil, The transcriptome of rabbit conjunctiva in dry eye disease: Large-scale changes and similarity to the human dry eye, PLoS ONE 16(7): e0254036. 2021.

Immunology

Panda, Aruna; Tatarov, Ivan; Melton-Celsa, Angela R; Kolappaswamy, Krishnan; Kriel, Edwin H; Petkov, Daniel; Coksaygan, Turhan; Livio, Sofie; McLeod, Charles G; Nataro, James P; OBrien, Alison D; DeTolla, Louis J;, Escherichia coli O157:H7 infection in Dutch belted and New Zealand White Rabbits., Comparative medicine Vol.60, 2010
Rodrigues, Gerard A; Mason, Matthew; Christie, Lori-Ann; Hansen, Candice; Hernandez, Lisa M; Burke, James; Luhrs, Keith A; Hohman, Thomas C;, Functional Characterization of Abicipar-Pegol, an Anti-VEGF DARPin Therapeutic That Potently Inhibits Angiogenesis and Vascular Permeability., Investigative ophthalmology & visual science Vol.59, 2018
Lei, Hetian; Velez, Gisela; Hovland, Peter; Hirose, Tatsuo; Gilbertson, Debra; Kazlauskas, Andrius;, Growth factors outside the PDGF family drive experimental PVR., Investigative ophthalmology & visual science Vol.50, 2009
Reemers S, Peeters L, van Schijndel J, Bruton B, Sutton D, van der Waart L, van de Zande S., Novel Trivalent Vectored Vaccine for Control of Myxomatosis and Disease Caused by Classical and a New Genotype of Rabbit Haemorrhagic Disease Virus, Vaccines (Basel). 2020 Aug 5;8(3):441. doi: 10.3390/vaccines8030441.
Pfeffer, Bruce A; Bernstein, Steven A; Bartels, Stephen P;, Preservation of structure and immunoreactivity at the vitreoretinal interface of the rabbit eye., Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie Vol.247, 2009
Xue, Kun; Zhao, Xinxin; Zhang, Zhongxing; Qiu, Beiying; Tan, Queenie Shu Woon; Ong, Kok Haur; Liu, Zengping; Parikh, Bhav Harshad; Barathi, Veluchamy Amutha; Yu, Weimiao; Wang, Xiaomeng; Lingam, Gopal; Hunziker, Walter; Su, Xinyi; Loh, Xian Jun;, Sustained delivery of anti-VEGFs from thermogel depots inhibits angiogenesis without the need for multiple injections., Biomaterials science Vol.7, 2019

Neuroscience

Haragopal H, Dorkoski R, Johnson HM, Berryman MA, Tanda S, Day ML., Paired measurements of cochlear function and hair cell count in Dutch-belted rabbits with noise-induced hearing loss, Hear Res. 2020 Jan;385:107845. doi: 10.1016/j.heares.2019.107845. Epub 2019 Nov 15.
Haragopal H, Dorkoski R, Pollard AR, Whaley GA, Wohl TR, Stroud NC, Day ML., Specific loss of neural sensitivity to interaural time difference of unmodulated noise stimuli following noise-induced hearing loss, J Neurophysiol. 2020 Oct 1;124(4):1165-1182. doi: 10.1152/jn.00349.2020. Epub 2020 Aug 26.
Dorkoski R, Hancock KE, Whaley GA, Wohl TR, Stroud NC, Day ML., Stimulus-frequency-dependent dominance of sound localization cues across the cochleotopic map of the inferior colliculus, J Neurophysiol. 2020 May 1;123(5):1791-1807. doi: 10.1152/jn.00713.2019. Epub 2020 Mar 18.

Pharmacology

Luu KT, Seal JR, Attar M., A Mechanistic and Translational Pharmacokinetic-Pharmacodynamic Model of Abicipar Pegol and Vascular Endothelial Growth Factor Inhibition, J Pharmacol Exp Ther. 2020 May;373(2):184-192. doi: 10.1124/jpet.119.263178. Epub 2020 Feb 25.
Lei, Hetian; Rheaume, Marc-Andre; Cui, Jing; Mukai, Shizuo; Maberley, David; Samad, Arif; Matsubara, Joanne; Kazlauskas, Andrius;, A novel function of p53: a gatekeeper of retinal detachment., The American journal of pathology Vol.181, 2012
Li, Yong; Busoy, Joanna Marie; Zaman, Ben Alfyan Achirn; Tan, Queenie Shu Woon; Tan, Gavin Siew Wei; Barathi, Veluchamy Amutha; Cheung, Ning; Wei, Jay Ji-Ye; Hunziker, Walter; Hong, Wanjin; Wong, Tien Yin; Cheung, Chui Ming Gemmy, A novel model of persistent retinal neovascularization for the development of sustained anti-VEGF therapies., xperimental eye research Vol.174, 2018
Grierson I, Minckler D, Rippy MK, Marshall AJ, Collignon N, Bianco J, Detry B, Johnstone MA., A novel suprachoroidal microinvasive glaucoma implant: in vivo biocompatibility and biointegration, BMC Biomed Eng. 2020 Oct 14;2:10. doi: 10.1186/s42490-020-00045-1. eCollection 2020.
Lin K, Cabral P, Ekpenyong O, El Bader S, Galvao J, Kim Y, Lu SX, Tam YT, Bruder M, Rearden P, Shankaran H, Beaumont M., A Surrogate Matrix-Based Approach Toward Multiplexed Quantitation of an sGC Stimulator and cGMP in Ocular Tissue and Plasma, Toxicol Pathol. 2020 Aug 27:192623320948836. doi: 10.1177/0192623320948836. Online ahead of print.
Lin, Kenneth; Cabral, Pablo; Ekpenyong, Oscar; Bader, Suzy El; Galvao, Joana; Kim, Yeonil; Lu, Sherry X.; Tam, Yu Tong; Bruder, Marc; Rearden, Paul; Shankaran, Harish; Beaumont, Maribel, A Surrogate Matrix-Based Approach Toward Multiplexed Quantitation of an sGC Stimulator and cGMP in Ocular Tissue and Plasma, Toxicologic Pathology. Toxicologic Pathology. 2021;49(3):544-554.
Qiu, Beiying; Tan, Alison; Veluchamy, Amutha Barathi; Li, Yong; Murray, Hannah; Cheng, Wei; Liu, Chenghao; Busoy, Joanna Marie; Chen, Qi-Yin; Sistla, Srivani; Hunziker, Walter; Cheung, Chui Ming Gemmy; Wong, Tien Yin; Hong, Wanjin; Luesch, Hendrik; Wang, Xiaomeng;, Apratoxin S4 Inspired by a Marine Natural Product, a New Treatment Option for Ocular Angiogenic Diseases., Investigative ophthalmology & visual science Vol.60, 2019
Senapati S, Youssef AAA, Sweeney C, Cai C, Dudhipala N, Majumdar S., Cannabidiol Loaded Topical Ophthalmic Nanoemulsion Lowers Intraocular Pressure in Normotensive Dutch-Belted Rabbits, Pharmaceutics. 2022 Nov 24;14(12):2585. doi: 10.3390/pharmaceutics14122585.
Naderian, A; Bussières, L; Thomas, S; Lesage, F; Casanova, C;, Cellular origin of intrinsic optical signals in the rabbit retina, Vision research Vol.137, 2017
Chauchat, L., Guerin, C., Kaluzhny, Y., & Renard, J. P., Comparison of In Vitro Corneal Permeation and In Vivo Ocular Bioavailability in Rabbits of Three Marketed Latanoprost Formulations, European journal of drug metabolism and pharmacokinetics, 48(6), 633–645.
Hays, Cassandra L; Okafor, Kingsley C; Fan, Shan; High, Robin; Singh, Dhirendra P; Toris, Carol B;, Consequences of Puberty on Efficacy of Intraocular Pressure-Lowering Drugs in Male Dutch-Belted Rabbits., Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.34,
Nguyen, Van Phuc; Li, Yanxiu; Qian, Wei; Liu, Bing; Tian, Chao; Zhang, Wei; Huang, Ziyi; Ponduri, Arjun; Tarnowski, Madison; Wang, Xueding; Paulus, Yannis M;, Contrast Agent Enhanced Multimodal Photoacoustic Microscopy and Optical Coherence Tomography for Imaging of Rabbit Choroidal and Retinal Vessels in vivo, Scientific reports Vol.9, 2019
Boyer DD, Ko YP, Podos SD, Cartwright ME, Gao X, Wiles JA, Huang M., Danicopan, an Oral Complement Factor D Inhibitor, Exhibits High and Sustained Exposure in Ocular Tissues in Preclinical Studies, Transl Vis Sci Technol. 2022 Oct 3;11(10):37. doi: 10.1167/tvst.11.10.37.
Tom I, Pham VC, Katschke KJ Jr, Li W, Liang WC, Gutierrez J, Ah Young A, Figueroa I, Eshghi ST, Lee CV, Kanodia J, Snipas SJ, Salvesen GS, Lai P, Honigberg L, van Lookeren Campagne M, Kirchhofer D, Baruch A, Lill JR., Development of a therapeutic anti-HtrA1 antibody and the identification of DKK3 as a pharmacodynamic biomarker in geographic atrophy, Proc Natl Acad Sci U S A. 2020 May 5;117(18):9952-9963. doi: 10.1073/pnas.1917608117. Epub 2020 Apr 28.
Roy Chowdhury, Uttio; Rinkoski, Tommy A; Bahler, Cindy K; Millar, J Cameron; Bertrand, Jacques A; Holman, Bradley H; Sherwood, Joseph M; Overby, Darryl R; Stoltz, Kristen L; Dosa, Peter I; Fautsch, Michael P;, Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents., Investigative ophthalmology & visual science Vol.58, 2017
Ibrahim MM, Maria DN, Wang X, Simpson RN, Hollingsworth TJ, Jablonski MM., Enhanced Corneal Penetration of a Poorly Permeable Drug Using Bioadhesive Multiple Microemulsion Technology, Pharmaceutics. 2020 Jul 26;12(8):704. doi: 10.3390/pharmaceutics12080704.
Dong L, Han H, Huang X, Ma G, Fang D, Qi H, Han Z, Wang L, Tian J, Vanhaesebroeck B, Zhang G, Zhang S, Lei H., Idelalisib inhibits experimental proliferative vitroretinopathy, Lab Invest. 2022 Dec;102(12):1296-1303. doi: 10.1038/s41374-022-00822-7. Epub 2022 Jul 19.
Li, Hanxuan; Ibrahim, Mohamed Moustafa; Chen, Hao; Li, Wei; Jablonski, Monica M., In Silico Screening and In Vivo Evaluation of Potential CACNA2D1 Antagonists as Intraocular Pressure-Reducing Agents in Glaucoma Therapy, Pharmaceuticals 2021, 14(9), 887.
Schwarz F, John G, Becker J, Grötz KA, Sader R, Mihatovic I., Influence of ridge preservation procedures on extraction socket healing under antiresorptive therapy: An experimental study in rabbits, Clin Implant Dent Relat Res. 2020 Aug;22(4):477-485. doi: 10.1111/cid.12916. Epub 2020 Jun 15.
Zhou C, Singh A, Qian G, Wolkow N, Dohlman CH, Vavvas DG, Chodosh J, Paschalis EI., Microporous Drug Delivery System for Sustained Anti-VEGF Delivery to the Eye, Transl Vis Sci Technol. 2020 Jul 2;9(8):5. doi: 10.1167/tvst.9.8.5. eCollection 2020 Jul.
Torrens I, Ganza Á, Hernández G, Gonzalo A, Zazpe A., Ocular Biodistribution of Once-Daily 0.6% Bilastine Eye Drops Reveals Highest Levels in Conjunctiva Up to 24 h Postadministration, J Ocul Pharmacol Ther. 2022 Nov;38(9):617-625. doi: 10.1089/jop.2022.0024. Epub 2022 Oct 21.
Askew, Ben C; Furuya, Takeru; Edwards, D Scott;, Ocular Distribution and Pharmacodynamics of SF0166, a Topically Administered ιvβ3 Integrin Antagonist, for the Treatment of Retinal Diseases., The Journal of pharmacology and experimental therapeutics Vol.366, 2018
Shen, Jie; Durairaj, Chandra; Lin, Ton; Liu, Yan; Burke, James;, Ocular pharmacokinetics of intravitreally administered brimonidine and dexamethasone in animal models with and without blood-retinal barrier breakdown., Investigative ophthalmology & visual science Vol.55, 2014
Haragopal, Hariprakash; Dorkoski, Ryan; Johnson, Holly M; Berryman, Mark A; Tanda, Soichi; Day, Mitchell L;, Paired measurements of cochlear function and hair cell count in Dutch-belted rabbits with noise-induced hearing loss, Hearing research Vol.385, 2020
Huang, Wei; Wen, Ziyi; Saglam, Muhammet S.; Huang, Liqun; Honkanen, Robert A.; Rigas, Basil, Phospho-Sulindac (OXT-328) Inhibits Dry Eye Disease in Rabbits: A Dose-, Formulation- and Structure-Dependent Effect, Journal of Ocular Pharmacology and Therapeutics. Aug 2021.321-330.
Roy Chowdhury U, Pervan-Steel CL, Sheeler R, Sookdeo HK, Rogers B, Casale R, Dosa PI, Htoo T, Wirostko BM, Fautsch MP., Preclinical Pharmacokinetic Profile of Topical Ophthalmic and Intravenous Delivery of QLS-101, a Novel ATP-Sensitive Potassium Channel Opening Ocular Hypotensive Agent, J Ocul Pharmacol Ther. 2023 Jun;39(5):332-346. doi: 10.1089/jop.2022.0184. Epub 2023 May 17.
Glogowski, Shellise; Lowe, Ezra; Siou-Mermet, Raphaele; Ong, Tuyen; Richardson, Mary;, Prolonged exposure to loteprednol etabonate in human tear fluid and rabbit ocular tissues following topical ocular administration of Lotemax gel, 0.5%., Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.30, 2014
Pennock, Steven; Kim, David; Mukai, Shizuo; Kuhnle, Matthew; Chun, Dal W; Matsubara, Joanne; Cui, Jing; Ma, Patrick; Maberley, David; Samad, Arif; Van Geest, Robert J; Oberstein, Sarit L; Schlingemann, Reinier O; Kazlauskas, Andrius;, Ranibizumab is a potential prophylaxis for proliferative vitreoretinopathy, a nonangiogenic blinding disease., The American journal of pathology Vol.182, 2013
Cavet, Megan E; Glogowski, Shellise; Lowe, Ezra R; Phillips, Eric;, Rheological Properties, Dissolution Kinetics, and Ocular Pharmacokinetics of Loteprednol Etabonate (Submicron) Ophthalmic Gel 0.38., Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.35, 2019
Zhou, Chengxin; Robert, Marie-Claude; Kapoulea, Vassiliki; Lei, Fengyang; Stagner, Anna M; Jakobiec, Frederick A; Dohlman, Claes H; Paschalis, Eleftherios I;, Sustained Subconjunctival Delivery of Infliximab Protects the Cornea and Retina Following Alkali Burn to the Eye., Investigative ophthalmology & visual science Vol.58, 2017
Paschalis EI, Zhou C, Sharma J, Dohlman TH, Kim S, Lei F, Chodosh J, Vavvas D, Urtti A, Papaliodis G, Dohlman CH., The prophylactic value of TNF-α inhibitors against retinal cell apoptosis and optic nerve axon loss after corneal surgery or trauma, Acta Ophthalmol. 2023 Oct 6. doi: 10.1111/aos.15786. Online ahead of print.
Paschalis EI, Zhou C, Sharma J, Kim S, Lei F, Chodosh J, Vavvas D, Urtti A, Papaliodis G, Dohlman CH., The prophylactic value of TNF-α inhibitors against retinal ganglion cell and optic nerve axon loss after corneal surgery or trauma, bioRxiv 2022.10.06.510713.
Zyablitskaya M, Jayyosi C, Takaoka A, Myers KM, Suh LH, Nagasaki T, Trokel SL, Paik DC., Topical Corneal Cross-Linking Solution Delivered Via Corneal Reservoir in Dutch-Belted Rabbits, Transl Vis Sci Technol. 2020 Aug 11;9(9):20. doi: 10.1167/tvst.9.9.20. eCollection 2020 Aug.
Ghosn, Corine R; Li, Yong; Orilla, Werhner C; Lin, Ton; Wheeler, Larry; Burke, James A; Robinson, Michael R; Whitcup, Scott M;, Treatment of experimental anterior and intermediate uveitis by a dexamethasone intravitreal implant., Investigative ophthalmology & visual science Vol.52, 2011

Teratology

Wise, L David; Turner, Katie J; Kerr, Janet S;, Assessment of developmental toxicity of vorinostat, a histone deacetylase inhibitor, in Sprague-Dawley rats and Dutch Belted Rabbit., Birth defects research. Part B, Developmental and reproductive toxicology Vol.80, 2007
Crofts, F; Pino, M; DeLise, B; Guittin, P; Barbellion, S; Brunel, P; Potdevin, S; Bergmann, B; Hofmann, T; Lerman, S; Clark, R L;, Different embryo-fetal toxicity effects for three VLA-4 antagonists., Birth defects research. Part B, Developmental and reproductive toxicology Vol.71, 2004

Toxicology

Bantseev, Vladimir; Parker, Sara; Andaya, Roxanne; Schuetz, Chris; Christian, Brian; Miller, Paul E; Booler, Helen; Schutten, Melissa, Determination of a No Observed Effect Level (NOEL) for Beta Glucans following a Single Intravitreal Administration to Female Dutch Belted Rabbit, Investigative Ophthalmology & Visual Science. ARVO Annual Meeting Abstract . June 2021.
Bantseev, Vladimir; Miller, Paul E; Bentley, Ellison; Schuetz, Chris; Streit, Tim M; Christian, Brian J; Farman, Cindy; Booler, Helen; Thackaberry, Evan A;, Determination of a No-Observable Effect Level for Endotoxin Following a Single Intravitreal Administration to Dutch Belted Rabbit, Investigative ophthalmology & visual science Vol.58, 2017
Thackaberry, Evan A; Farman, Cynthia; Bantseev, Vladimir; Schuetz, Chris; Baker, Julia F; Brown, Michael H; Learn, Douglas B;, Intravitreal administration of known phototoxicants in the rabbit fails to produce phototoxicity: implications for phototoxicity testing of intravitreally administered small molecule therapeutics., Cutaneous and ocular toxicology Vol.34, 2015
Sorden SD, Larsen T, McPherson LE, Turner OC, Carroll EE, Sharma AK., Spontaneous Background and Procedure-Related Microscopic Findings and Common Artifacts in Ocular Tissues of Laboratory Animals in Ocular Studies, Toxicol Pathol. 2020 Nov 18:192623320966244. doi: 10.1177/0192623320966244. Online ahead of print.
Spence, Stan;, The Dutch-Belted rabbit: an alternative breed for developmental toxicity testing. Birth defects research., Part B, Developmental and reproductive toxicology Vol.68, 2003
Pelletier, Jesse S; Devine, John; Capriotti, Kara; Barone, Samuel B; Capriotti, Joseph A;, Topical application of povidone-iodine/dimethylsulfoxide ophthalmic gel preparation in Dutch-Belted rabbits., Cutaneous and ocular toxicology Vol.38, 2019
Solano, Elisabeth C R; Kornbrust, Douglas J; Beaudry, Amber; Foy, Jeffrey W-D; Schneider, David J; Thompson, James D;, Toxicological and pharmacokinetic properties of QPI-1007, a chemically modified synthetic siRNA targeting caspase 2 mRNA, following intravitreal injection., Nucleic acid therapeutics Vol.24, 2014

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