HsdHre:Beagles
Related publications
Cellular therapies
Brott, David A; Katein, Anne; Thomas, Heath; Lawton, Michael; Montgomery, Robert R; Richardson, Rudy J; Louden, Calvert S;, Evaluation of von Willebrand factor and von Willebrand factor propeptide in models of vascular endothelial cell activation, perturbation, and/or injury., Toxicologic pathology Vol.42, 2014
Wi, H., Lee, S., Kim, Y., No, J. G., Lee, P., Lee, B. R., ... & Ock, S. A., Immunosuppression-enhancing effect of the administration of allogeneic canine adipose-derived mesenchymal stem cells (cA-MSCs) compared with autologous cA-MSCs in vitro, Journal of Veterinary Science 22, no. 5 (2021).
Applefeld WN, Wang J, Sun J, Pockros BM, Solomon SB, Feng J, Risoleo T, Cortés-Puch I, Gouél-Cheron A, Klein HG, Natanson C., In canine bacterial pneumonia circulating granulocyte counts determine outcome from donor cells, Transfusion. 2020 Apr;60(4):698-712. doi: 10.1111/trf.15727. Epub 2020 Feb 22.
Doi, Takuya; Tomonari, Yuki; Kawasako, Kazufumi; Yamada, Naoaki; Tsuchitani, Minoru;, Lymphocytic adrenal medullitis and lymphocytic thyroiditis in a laboratory beagle dog., The Journal of veterinary medical science Vol.79, 2017
Vrecenak, Jesse D; Pearson, Erik G; Todorow, Carlyn A; Li, Haiying; Johnson, Mark P; Flake, Alan W;, Preclinical Canine Model of Graft-versus-Host Disease after In Utero Hematopoietic Cell Transplantation., Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation Vol.24, 2018
Vrecenak, Jesse D; Pearson, Erik G; Santore, Matthew T; Todorow, Carlyn A; Li, Haiying; Radu, Antoneta; Bhatti, Tricia; Peranteau, William H; Johnson, Mark P; Flake, Alan W;, Stable long-term mixed chimerism achieved in a canine model of allogeneic in utero hematopoietic cell transplantation., Blood Vol.124, 2014
McGill, Jodi L; Nair, Arathy D S; Cheng, Chuanmin; Rusk, Rachel A; Jaworski, Deborah C; Ganta, Roman R;, Vaccination with an Attenuated Mutant of Ehrlichia chaffeensis Induces Pathogen-Specific CD4+ T Cell Immunity and Protection from Tick-Transmitted Wild-Type Challenge in the Canine Host, PloS one Vol.11, 2016
General studies
Yoo, Yeon-Jee; Perinpanayagam, Hiran; Choi, Youngnim; Gu, Yu; Chang, Seok-Woo; Baek, Seung-Ho; Zhu, Qiang; Fouad, Ashraf F.; Kum, Kee-Yeon, Characterization of Histopathology and Microbiota in Contemporary Regenerative Endodontic Procedures: Still Coming up Short, Journal of Endodontics. 2021.
Rossman EI, Cools F, Cordes J, Dhuyvetter D, Doyle JM, Friedrichs GS, Guth B, Neradilek MB, Parish ST, Pierson JB, Polissar N, Tang HM., Echocardiographic and hemodynamic indices of myocardial contractility simultaneously evaluated in telemetered beagle dogs: A HESI-sponsored cross-company evaluation, J Pharmacol Toxicol Methods. 2020 Sep;105:106897. doi: 10.1016/j.vascn.2020.106897. Epub 2020 Jul 12.
Petruska, Janet M.; Adamo, Maria; McCartney, Jeffrey; Aboulmali, Ahamat; Rosol, Thomas J., Evaluation of Adrenal Cortical Function in Neonatal and Weanling Laboratory Beagle Dogs, Toxicologic Pathology. 2021.
Olías-Molero AI, Moreno I, Corral MJ, Jiménez-Antón MD, Day MJ, Domínguez M, Alunda JM., Infection of dogs by Leishmania infantum elicits a general response of IgG subclasses, Sci Rep. 2020 Nov 2;10(1):18826. doi: 10.1038/s41598-020-75569-6.
Uchida, Mitsuhiro; Ito, Fumi; Tsuchiya, Toshiyuki; Shoji, Yoko; Kurosawa, Toru;, Novel phenotype in beagle dogs characterized by skin response to compound 48/80 focusing on skin mast cell degranulation., Experimental animals Vol.64, 2015
Baublits, Joel; Vargas, Hugo M.; Engwall, Michael J., The in vivo QTc core assay: An evaluation of QTc variability, detection sensitivity and implications for the improvement of conscious dog and non-human primate telemetry studies, Journal of Pharmacological and Toxicological Methods. 2021.
Ocular studies
Durairaj, Chandrasekar; Shen, Jie; Cherukury, Madhu;, based translational pharmacokinetic - pharmacodynamic model to predict intraocular pressure lowering effect of drugs in patients with glaucoma or ocular hypertension., Pharmaceutical research Vol.31, 2014
Lee, Susan S; Burke, James; Shen, Jie; Almazan, Alexandra; Orilla, Werhner; Hughes, Patrick; Zhang, Jane; Li, Huajiang; Struble, Craig; Miller, Paul E; Robinson, Michael R, Bimatoprost sustained-release intracameral implant reduces episcleral venous pressure in dogs., Veterinary ophthalmology Vol.21, 2018
Gronkiewicz, K M; Giuliano, E A; Kuroki, K; Bunyak, F; Sharma, A; Teixeira, L B C; Hamm, C W; Mohan, R R;, Development of a novel in vivo corneal fibrosis model in the dog., Experimental eye research Vol.143, 2016
Gronkiewicz, Kristina M; Giuliano, Elizabeth A; Sharma, Ajay; Mohan, Rajiv R;, Effects of topical hyaluronic acid on corneal wound healing in dogs: a pilot study., Veterinary ophthalmology Vol.20, 2017
Mowat, Freya M; Wise, Elisabeth; Oh, Annie; Foster, Melanie L, In vivo electroretinographic differentiation of rod, short-wavelength and long/medium-wavelength cone responses in dogs using silent substitution stimuli., Experimental eye research Vol.185, 2019
Seal, Jennifer R; Robinson, Michael R; Burke, James; Bejanian, Marina; Coote, Michael; Attar, Mayssa;, Intracameral Sustained-Release Bimatoprost Implant Delivers Bimatoprost to Target Tissues with Reduced Drug Exposure to Off-Target Tissues., Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.35,
Chung, Jou-Ku; Spencer, Elizabeth; Hunt, Matthew; McCauley, Thomas;, Ocular Distribution and Pharmacokinetics of Lifitegrast in Pigmented Rabbits and Mass Balance in Beagle Dogs., the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.34,
Mowat, F M; Gornik, K R; Dinculescu, A; Boye, S L; Hauswirth, W W; Petersen-Jones, S M; Bartoe, J T;, Tyrosine capsid-mutant AAV vectors for gene delivery to the canine retina from a subretinal or intravitreal approach., Gene therapy Vol.21, 2014
Pharmacology
Vick, Andrew; Wolff, Ronald; Koester, Alan; Reams, Rachel; Deaver, Daniel R; Heidel, Shawn, A 6-month inhalation study to characterize the toxicity, pharmacokinetics, and pharmacodynamics of human insulin inhalation powder (HIIP) in beagle dogs., Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine Vol.20, 2007
Kendrick J, Stow R, Ibbotson N, Adjin-Tettey G, Murphy B, Bailey G, Miller J, Helleberg H, Finderup Grove M, Ăvlisen K, Hansen JJ., A novel welfare and scientific approach to conducting dog metabolism studies allowing dogs to be pair housed, Lab Anim. 2020 Dec;54(6):588-598. doi: 10.1177/0023677220905330. Epub 2020 Feb 16.
Marier, J F; Beaudry, F; Ducharme, M P; Fortin, D; Moreau, J P; MassĂŠ, R; Vachon, P;, A pharmacokinetic study of amoxycillin in febrile beagle dogs following repeated administrations of endotoxin., Journal of veterinary pharmacology and therapeutics Vol.24, 2001
Ling, Xiang; Wu, Wenjie; Fan, Chuandong; Xu, Chao; Liao, Jianqun; Rich, Laurie J; Huang, Ruea-Yea; Repasky, Elizabeth A; Wang, Xinjiang; Li, Fengzhi, An ABCG2 non-substrate anticancer agent FL118 targets drug-resistant cancer stem-like cells and overcomes treatment resistance of human pancreatic cancer., Journal of experimental & clinical cancer research : CR Vol.37, 2018
Budachetri K, Teymournejad O, Lin M, Yan Q, Mestres-Villanueva M, Brock GN, Rikihisa Y., An Entry-Triggering Protein of Ehrlichia Is a New Vaccine Candidate against Tick-Borne Human Monocytic Ehrlichiosis, mBio. 2020 Jul 28;11(4):e00895-20. doi: 10.1128/mBio.00895-20.
Baird, Theodore J; Aulbach, Adam; ODonohue, Kyle P; Yoder, Joshua D; Dalton, Jill A; Gauvin, David V;, Background variability in standard clinical pathology biomarkers in beagle dogs instrumented with chronic indwelling telemetry devices., Journal of pharmacological and toxicological methods Vol.69,
Ooms, Tara G; Way, Holly L; Bley, John A;, Clinical and hematological effects of serial phlebotomy performed on laboratory beagles., Contemporary topics in laboratory animal science Vol.43, 2004
Roberts A, Grafton G, Powell AD, Brock K, Chen C, Xie D, Huang J, Liu S, Cooper AJ, Brady CA, Qureshi O, Stamataki Z, Manning DD, Moore NA, Sargent BJ, Guzzo PR, Barnes NM., CSTI-300 (SMP-100); a Novel 5-HT(3) Receptor Partial Agonist with Potential to Treat Patients with Irritable Bowel Syndrome or Carcinoid Syndrome, J Pharmacol Exp Ther. 2020 Apr;373(1):122-134. doi: 10.1124/jpet.119.261008. Epub 2020 Feb 26.
Mitchell, Sheila M; Zajac, Anne M; Charles, Sam; Duncan, Robert B; Lindsay, David S;, Cystoisospora canis NemesĂŠri, 1959 (syn. Isospora canis), infections in dogs: clinical signs, pathogenesis, and reproducible clinical disease in beagle dogs fed oocysts., The Journal of parasitology Vol.93, 2007
Wilson, James P; Cobb, Ronald R; Dungan, Nathanael W; Matthews, Laura L; Eppler, Bärbel; Aiello, Kenneth V; Curtis, Shiro; Boger, Teannetta; Guilmette, Raymond A; Weber, Waylon; Doyle-Eisele, Melanie; Talton, James D;, Decorporation of systemically distributed americium by a novel orally administered diethylenetriaminepentaacetic acid (DTPA) formulation in beagle dogs., Health physics Vol.108, 2015
Dhollander, Aad; Malone, Amanda; Price, James; Getgood, Alan;, Determination of knee cartilage volume and surface area in beagle dogs, a pilot study. Journal of experimental orthopaedics Vol.4, 2017
Shen J, Moats RA, Pollack HA, Robinson MR, Attar M., Distribution of (14)C-Latanoprost Following a Single Intracameral Administration Versus Repeated Topical Administration, Ophthalmol Ther. 2020 Dec;9(4):929-940. doi: 10.1007/s40123-020-00285-3. Epub 2020 Aug 1.
Houle, Christopher D; Finch, Gregory L; Mauthe, Robert J; Potter, David M; Walisser, Jacqueline A; Gardner, Iain B; DeWit, Robert H;, Effects of lersivirine on canine and rodent thyroid function., Toxicologic pathology Vol.42, 2014
Borron, Stephen W; Stonerook, Michael; Reid, Frances, Efficacy of hydroxocobalamin for the treatment of acute cyanide poisoning in adult beagle dogs., Clinical toxicology (Philadelphia, Pa.) Vol.44 Suppl 1, 2006
Kremer, John J; Bills, Andrew J; Hanke, Nathanael J; Chen, Hepei; Meier, William A; Osinski, Mark A; Foley, C Michael;, Evaluation of cardiovascular changes in dogs administered three positive controls using jacketed external telemetry-blood pressure (JET-BP)., Journal of pharmacological and toxicological methods Vol.75,
Chui, R. W., Baublits, J., Chandra, F. A., Jones, Z. W., Engwall, M. J., & Vargas, H. M., Evaluation of moxifloxacin in canine and non?human primate telemetry assays: Comparison of QTc interval prolongation by timepoint and concentration?QTc analysis, Clinical and translational science 14.6 (2021): 2379-2390.
Richards D, Bamford M, Liefaard L, Haque N, Lewis G, Storey J, Fernando D, Kumar S, Thompson D, Holmes DS., Identification, preclinical profile, and clinical proof of concept of an orally bioavailable pro-drug of miridesap, Br J Pharmacol. 2020 Apr;177(8):1853-1864. doi: 10.1111/bph.14956. Epub 2020 Feb 11.
Lee, David S H; Pai, Y; Chang, Steve; Kim, D H;, Microstructure, physical properties, and bone regeneration effect of the nano-sized ?--tricalcium phosphate granules., Materials science & engineering. C, Materials for biological applications Vol.58, 2016
Highland, Jaclyn N; Morris, Patrick J; Zanos, Panos; Lovett, Jacqueline; Ghosh, Soumita; Wang, Amy Q; Zarate, Carlos A; Thomas, Craig J; Moaddel, Ruin; Gould, Todd D;, Mouse, rat, and dog bioavailability and mouse oral antidepressant efficacy of ( 2R,6R)-hydroxynorketamine., Journal of psychopharmacology (Oxford, England) Vol.75, 2018
Shin HW, Kim JE, Park YJ., Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs, Pharmaceutics. 2021 Jan 6;13(1):E63. doi: 10.3390/pharmaceutics13010063.
Shin, Hey-Won; Kim, Joo-Eun; Park, Young-Joon, Nanoporous Silica Entrapped Lipid-Drug Complexes for the Solubilization and Absorption Enhancement of Poorly Soluble Drugs, Pharmaceutics. 2021.
Shen J, Robinson MR, Struble C, Attar M., Nonclinical Pharmacokinetic and Pharmacodynamic Assessment of Bimatoprost Following a Single Intracameral Injection of Sustained-Release Implants, Transl Vis Sci Technol. 2020 Mar 20;9(4):20. doi: 10.1167/tvst.9.4.20. eCollection 2020 Mar.
Mudie DM, Stewart AM, Biswas N, Brodeur TJ, Shepard KB, Smith A, Morgen MM, Baumann JM, Vodak DT., Novel High-Drug-Loaded Amorphous Dispersion Tablets of Posaconazole; In Vivo and In Vitro Assessment, Mol Pharm. 2020 Dec 7;17(12):4463-4472. doi: 10.1021/acs.molpharmaceut.0c00471. Epub 2020 Sep 4.
Cekanova M, Pandey S, Olin S, Ryan P, Stokes JE, Hecht S, Martin-Jimenez T, Uddin MJ, Marnett LJ., Pharmacokinetic characterization of fluorocoxib D, a cyclooxygenase-2-targeted optical imaging agent for detection of cancer, J Biomed Opt. 2020 Aug;25(8):086005. doi: 10.1117/1.JBO.25.8.086005.
Bruss, M L; Margolin, S B; Giri, S N;, Pharmacokinetics of orally administered pirfenidone in male and female beagles., Journal of veterinary pharmacology and therapeutics Vol.27, 2004
Wong, H; Chen, J Z; Chou, B; Halladay, J S; Kenny, J R; La, H; Marsters, J C; Plise, E; Rudewicz, P J; Robarge, K; Shin, Y; Wong, S; Zhang, C; Khojasteh, S C;, Preclinical assessment of the absorption, distribution, metabolism and excretion of GDC-0449 (2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide), an orally bioavailable systemic Hedgehog signalling pathway inhibitor., Xenobiotica; the fate of foreign compounds in biological systems Vol.39, 2009
Whiting, Roger L.; Choppin, Agnes; Luehr, Gary; Jasper, Jeffrey R., Preclinical Evaluation of the Effects of Trazpiroben (TAK-906), a Novel, Potent Dopamine D2/D3 Receptor Antagonist for the Management of Gastroparesis, Journal of Pharmacology and Experimental Therapeutics. 2021.
Shibata, Masakazu; Masuda, Masatoshi; Sasahara, Katsunori; Sasabe, Hiroyuki; Sasaki, Tomohiro; Kim, Seongryul; Takeuchi, Kenji; Umehara, Ken; Kashiyama, Eiji, Prediction of Human Pharmacokinetic Profiles of the Antituberculosis Drug Delamanid from Nonclinical Data: Potential Therapeutic Value against Extrapulmonary Tuberculosis, Antimicrobial Agents and Chemotherapy. 2021.
Petersson C, Papasouliotis O, Lecomte M, Badolo L, Dolgos H., Prediction of volume of distribution in humans: analysis of eight methods and their application in drug discovery, Xenobiotica. 2020 Mar;50(3):270-279. doi: 10.1080/00498254.2019.1625084. Epub 2019 Jun 19.
Hayes AW, Pressman P, Moser P, Soares-da-Silva P., Regulatory safety pharmacology evaluation of BIA 10-2474, J Pharmacol Toxicol Methods. 2020 Mar-Apr;102:106677. doi: 10.1016/j.vascn.2020.106677. Epub 2020 Jan 22.
Venkatasubramanian R, Collins TA, Lesko LJ, Mettetal JT, Trame MN., Semi-mechanistic modelling platform to assess cardiac contractility and haemodynamics in preclinical cardiovascular safety profiling of new molecular entities, Br J Pharmacol. 2020 Aug;177(15):3568-3590. doi: 10.1111/bph.15079. Epub 2020 Jun 18.
Mitchell, Andrea Z; McMahon, Carrie; Beck, Tom W; Sarazan, R Dustan;, Sensitivity of two noninvasive blood pressure measurement techniques compared to telemetry in cynomolgus monkeys and beagle dogs., Journal of pharmacological and toxicological methods Vol.62,
Wang T, Babusis D, Park Y, Niu C, Kim C, Zhao X, Lu B, Ma B, Muench RC, Sperger D, Ray AS, Murakami E., Species differences in liver accumulation and metabolism of nucleotide prodrug sofosbuvir, Drug Metab Pharmacokinet. 2020 Jun;35(3):334-340. doi: 10.1016/j.dmpk.2020.04.333. Epub 2020 Apr 16.
Guth, Brian D; Chiang, Alan Y; Doyle, Jennifer; Engwall, Michael J; Guillon, Jean-Michel; Hoffmann, Peter; Koerner, John; Mittelstadt, Scott; Ottinger, Sean; Pierson, Jennifer Beck; Pugsley, Michael K; Rossman, Eric I; Walisser, Jacqueline; Sarazan, R Dustan, The evaluation of drug-induced changes in cardiac inotropy in dogs, Results from a HESI-sponsored consortium. Journal of pharmacological and toxicological methods Vol.75,
the official journal of the Association for Ocular Pharmacology and Therapeutics Vol.34,, The pharmacokinetics of oclacitinib maleate, a Janus kinase inhibitor, in the dog., The pharmacokinetics of oclacitinib maleate, a Janus kinase inhibitor, in the dog.
Takahashi, Ryan H; Chang, Jae H; Pang, Jodie; Liang, Xiaorong; Ma, Shuguang;, Unequal Absorption of Radiolabeled and Nonradiolabeled Drug from the Oral Dose Leads to Incorrect Estimates of Drug Absorption and Circulating Metabolites in a Mass Balance Study., Drug metabolism letters Vol.13, 2019
Toxicology
Petruska, Janet M; Remick, Amera K; Lejeune, Typhaine; Vezina, Mark; Robinson, Keith; Bussières, Martin; Gilger, Brian C; Dubielzig, Richard R;, A Transient Developmental Background Finding in the Retina Observed in Neonatal Dogs in Juvenile Toxicology Studies., Toxicologic pathology Vol.47, 2019
Holson, J F; Stump, D G; Pearce, L B; Watson, R E; DeSesso, J M;, Absence of developmental toxicity in a canine model after infusion of a hemoglobin-based oxygen carrier, Implications for risk assessment. Reproductive toxicology (Elmsford, N.Y.) Vol.52, 2015
Miller, G K; Valerio, M G; Pino, M V; Larson, J L; Viau, A; Hamelin, N; LabbĂŠ, R; Banks, C M;, Chronic effects of the novel glucocorticosteroid RPR 106541 administered to beagle dogs by inhalation., Toxicologic pathology Vol.28,
Byrd, Richard A; Blackbourne, Jamie L; Knadler, Mary Pat; Schultze, Albert E; Vahle, John L;, Chronic Toxicology Studies of Basal Insulin Peglispro in Rats and Dogs, A Novel, PEGylated Insulin Lispro Analog with a Prolonged Duration of Action. Toxicologic pathology Vol.45, 2017
Wallery, Jeffrey J.; Kale, Vijay Pralhad; Novak, Joseph; Gibbs, Seth; Do, Minh-Ha T.; McKew, John C.; Terse, Pramod S., Evaluation of chronic toxicity of cyclocreatine in beagle dogs after oral gavage administration for up to 23 weeks, Toxicology and Applied Pharmacology. 2021.
Mitsuishi, Mikio; Oshikata, Takafumi; Kumabe, Shino; Kobayashi, Azusa; Katoku, Koshiro; Kanno, Takeshi; Hamamura, Masao; Tsuchitani, Minoru, Histological dermal changes caused by preparation and application procedures in percutaneous dose toxicity studies in dogs, rabbits and rats., Journal of toxicologic pathology Vol.28, 2015
Bodié, Karen; Decker, Joshua H;, Incidental histopathological findings in hearts of control beagle dogs in toxicity studies., Toxicologic pathology Vol.42, 2014
Kerr, Janet S; Galloway, Sheila; Lagrutta, Armando; Armstrong, Michael; Miller, Thomas; Richon, Victoria M; Andrews, Paul A;, Nonclinical safety assessment of the histone deacetylase inhibitor vorinostat., International journal of toxicology Vol.29,
Watanabe, Dai; Nakara, Hiromi; Akagi, Keisuke; Ishii, Toshiya; Mizuguchi, Hiroyasu; Nagashima, Yoshikazu; Okaniwa, Azusa;, Oral glucose tolerance test and determination of serum fructosamine level in beagle dogs., The Journal of toxicological sciences Vol.29, 2004
Hardisty JF, Harris SB, Hayes WA, Weber K., Oral repeated-dose toxicity studies of BIA 10-2474 in beagle dogs, Regul Toxicol Pharmacol. 2020 Mar;111:104555. doi: 10.1016/j.yrtph.2019.104555. Epub 2019 Dec 23.
Huckle, James E; Sadgrove, Matthew P; Pacyniak, Erik; Leed, Marina G D; Weber, Waylon M; Doyle-Eisele, Melanie; Guilmette, Raymond A; Agha, Bushra J; Susick, Robert L; Mumper, Russell J; Jay, Michael, Orally administered DTPA di-ethyl ester for decorporation of (241)Am in dogs: Assessment of safety and efficacy in an inhalation-contamination model., International journal of radiation biology Vol.91, 2015
Katavolos P, Cain G, Farman C, Romero FA, Magnuson S, Ly JQ, Choo EF, Katakam AK, Andaya R, Maher J., Preclinical Safety Assessment of a Highly Selective and Potent Dual Small-Molecule Inhibitor of CBP/P300 in Rats and Dogs, Toxicol Pathol. 2020 Apr;48(3):465-480. doi: 10.1177/0192623319898469. Epub 2020 Mar 3.
Cass L, Murray A, Davis A, Woodward K, Albayaty M, Ito K, Strong P, Ayrton J, Brindley C, Prosser J, Murray J, French E, Haywood P, Wallis C, Rapeport G., Safety and nonclinical and clinical pharmacokinetics of PC945, a novel inhaled triazole antifungal agent, Pharmacol Res Perspect. 2021 Feb;9(1):e00690. doi: 10.1002/prp2.690.
Niven, Ralph; Lynch, Maryellen; Moutvic, Ronald; Gibbs, Seth; Briscoe, Crystal; Raff, Howard;, Safety and toxicology of cyclosporine in propylene glycol after 9-month aerosol exposure to beagle dogs., Journal of aerosol medicine and pulmonary drug delivery Vol.24, 2011
Terse, P. S., Peggins, J., & Seminara, S. B., Safety Evaluation of KP-10 (Metastin 4554) Following once Daily Intravenous Administration for 14 Days in Dog, International Journal of Toxicology. 2021;40(4):337-343.
Spence, S; Soper, K; Hoe, C M; Coleman, J;, The heart rate-corrected QT interval of conscious beagle dogs: a formula based on analysis of covariance., Toxicological sciences : an official journal of the Society of Toxicology Vol.45, 1998
