AHR knockout rats
Related publications
ADMET
Pohjanvirta R, Mahiout S., Aryl hydrocarbon receptor is indispensable for β-naphthoflavone-induced novel food avoidance and may be involved in LiCl-triggered conditioned taste aversion in rats., Physiol Behav. 2019 May 15;204:58-64.
Harrill JA, Layko D, Nyska A, Hukkanen RR, Manno RA, Grassetti A, Lawson M, Martin G, Budinsky RA, Rowlands JC, Thomas RS., Aryl hydrocarbon receptor knockout rats are insensitive to the pathological effects of repeated oral exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin., J Appl Toxicol. 2016 Jun;36(6):802-14.
Phadnis-Moghe AS, Chen W, Li J, Crawford RB, Bach A, D'Ingillo S, Kovalova N, Suarez-Martinez JE, Kaplan BL, Harrill JA, Budinsky R, Rowlands JC, Thomas RS, Kaminski NE., Immunological characterization of the aryl hydrocarbon receptor (AHR) knockout rat in the presence and absence of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)., Toxicology. 2016 Aug 10;368-369:172-182.
Harrill JA, Hukkanen RR, Lawson M, Martin G, Gilger B, Soldatow V, Lecluyse EL, Budinsky RA, Rowlands JC, Thomas RS., Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice., Toxicol Appl Pharmacol. 2013 Oct 15;272(2):503-18
Obesity
Pohjanvirta, R., Karppinen, I., Galbán-Velázquez, S., Esteban, J., Hĺkansson, H., Sankari, S., & Lindén, J., Effects of a high-fat diet and global aryl hydrocarbon receptor deficiency on energy balance and liver retinoid status in male Sprague-Dawley rats, The Journal of Nutritional Biochemistry 95 (2021): 108762.
