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    Purified high fat diets used to induce obesity and obesity-related complications such as diabetes and metabolic syndrome typically have 40-60% of energy derived from fat. The diet tables below summarize relevant diet features for several Teklad custom research diets commonly used in rodent models.

    Teklad also creates high-fat diets for other species, including pigs, primates, and dogs. Contact us to discuss the use of these diets or one that better meets your needs.

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    Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 55-60% of calories from fat

    Diet features TD.06414 stocked TD.93075 dough TD.07011 pellet
    Kcal/g 5.1 4.8 4.8
    Fat, % Kcal 60 55 55
    Fat Sources,% by weight 31% lard
    3% soybean oil
    27.4% vegetable shortening
    1.6% corn oil
    27.4% vegetable shortening
    1.6% corn oil
    Fatty acid profile, % total fat 36% saturated
    41% monounsaturated
    23% polyunsaturated
    23% saturated, 32% trans
    30% monounsaturated (cis)
    12% polyunsaturated (cis)
    23% saturated, 32% trans
    30% monounsaturated (cis)
    12% polyunsaturated (cis)
    Sucrose, % by weight 12.1 9.6 9.6
    Notes 60F10S poster data
    Compare to D12492
    Trans fat Trans fat
    Example modifications TD.08500 coconut oil
    TD.09766 milk fat
    Ingredient matched, low fat control diets* TD.06416 (35% sucrose)
    TD.08806 (11% sucrose)
    TD.93074 (21% sucrose)
    TD.120651 (7% sucrose)
    TD.93074 (21% sucrose)
    TD.120651 (7% sucrose)
    References Mouse
    Rat
    Mouse
    Rat
    Mouse
    Rat

    *Control diets can be designed in several ways, depending on what features the researcher wants to modify relative to the high-fat diet. These are just a few examples.

    Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 40-45% of calories from fat

    Diet features TD.06415 TD.08811 TD.88137 stocked TD.95217
    Kcal/g 4.6 4.7 4.5 4.3
    Fat, % Kcal 45 45 42 40
    Fat sources, % by weight 19.5% lard
    3% soybean oil
    21% milk fat
    2% soybean oil
    21% milk fat 10.6% vegetable shortening
    4% milk fat
    4% soybean oil
    Fatty acid profile,% total fat 35% saturated
    40% monounsaturated
    25% polyunsaturated
    61% saturated
    30% monounsaturated
    9% polyunsaturated
    66% saturated
    30% monounsaturated
    4% polyunsaturated
    31% saturated, 19% trans
    28% monounsaturated (cis)
    19% polyunsaturated (cis)
    Sucrose,% by weight 22.8 36.8 34.5 15.8
    Notes Compare to D12451 45F30S poster data "Western Diet"Cholesterol added Trans fat
    Example modifications TD.110716 milk fat
    TD.10670 no dye
    TD.130784 lard
    TD.120438 no dye
    TD.07201 lard
    TD.00573 h-coconut oil, no cholesterol
    TD.09682 blue dye
    TD.07734 green dye
    Ingredient matched, low fat control diets* TD.06416 (35% sucrose)
    TD.110675 (18% sucrose)
    TD.120455 (6% sucrose, resistant starch)
    TD.120724 (14% sucrose)
    TD.05230 (34% sucrose)
    TD.08485 (12% sucrose)
    TD.06101 (6% sucrose)
    References Mouse
    Rat
    Mouse
    Rat
    Mouse
    Rat
    Mouse
    Rat
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