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Purified high fat diets used to induce obesity and obesity-related complications such as diabetes and metabolic syndrome typically have 40-60% of energy derived from fat. The diet tables below summarize relevant diet features for several Teklad custom research diets commonly used in rodent models.

Teklad also creates high-fat diets for other species, including pigs, primates, and dogs. Contact us to discuss the use of these diets or one that better meets your needs.

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Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 55-60% of calories from fat

Diet features TD.06414 stocked TD.93075 dough TD.07011 pellet
Kcal/g 5.1 4.8 4.8
Fat, % Kcal 60 55 55
Fat Sources,% by weight 31% lard
3% soybean oil
27.4% vegetable shortening
1.6% corn oil
27.4% vegetable shortening
1.6% corn oil
Fatty acid profile, % total fat 36% saturated
41% monounsaturated
23% polyunsaturated
23% saturated, 32% trans
30% monounsaturated (cis)
12% polyunsaturated (cis)
23% saturated, 32% trans
30% monounsaturated (cis)
12% polyunsaturated (cis)
Sucrose, % by weight 12.1 9.6 9.6
Notes 60F10S poster data
Compare to D12492
Trans fat Trans fat
Example modifications TD.08500 coconut oil
TD.09766 milk fat
Ingredient matched, low fat control diets* TD.06416 (35% sucrose)
TD.08806 (11% sucrose)
TD.93074 (21% sucrose)
TD.120651 (7% sucrose)
TD.93074 (21% sucrose)
TD.120651 (7% sucrose)
References Mouse
Rat
Mouse
Rat
Mouse
Rat

*Control diets can be designed in several ways, depending on what features the researcher wants to modify relative to the high-fat diet. These are just a few examples.

Commonly-used diet-induced obesity (DIO) Teklad rodent diets with 40-45% of calories from fat

Diet features TD.06415 TD.08811 TD.88137 stocked TD.95217
Kcal/g 4.6 4.7 4.5 4.3
Fat, % Kcal 45 45 42 40
Fat sources, % by weight 19.5% lard
3% soybean oil
21% milk fat
2% soybean oil
21% milk fat 10.6% vegetable shortening
4% milk fat
4% soybean oil
Fatty acid profile,% total fat 35% saturated
40% monounsaturated
25% polyunsaturated
61% saturated
30% monounsaturated
9% polyunsaturated
66% saturated
30% monounsaturated
4% polyunsaturated
31% saturated, 19% trans
28% monounsaturated (cis)
19% polyunsaturated (cis)
Sucrose,% by weight 22.8 36.8 34.5 15.8
Notes Compare to D12451 45F30S poster data "Western Diet"Cholesterol added Trans fat
Example modifications TD.110716 milk fat
TD.10670 no dye
TD.130784 lard
TD.120438 no dye
TD.07201 lard
TD.00573 h-coconut oil, no cholesterol
TD.09682 blue dye
TD.07734 green dye
Ingredient matched, low fat control diets* TD.06416 (35% sucrose)
TD.110675 (18% sucrose)
TD.120455 (6% sucrose, resistant starch)
TD.120724 (14% sucrose)
TD.05230 (34% sucrose)
TD.08485 (12% sucrose)
TD.06101 (6% sucrose)
References Mouse
Rat
Mouse
Rat
Mouse
Rat
Mouse
Rat
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