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Doxycycline References

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  • Gross C, Zhuang X, Stark K, Ramboz S, Oosting R, Kirby L, Santarelli L, Beck S, Hen R. 2002. Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult.
    Nature 416:396-400.
  • Holmen SL, Williams BO. 2005. Essential role for Ras signaling in glioblastoma maintenance.
    Cancer Res 65:8250-8255.
  • Barraclough J, Hodgkinson C, Hogg A, Dive C, Welman A. 2007. Increases in c-Yes expression level and activity promote motility but not proliferation of human colorectal carcinoma cells.
    Neoplasia 9:745-754.
  • Bell EL, Emerling BM, Ricoult SJ, Guarente L. 2011. SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production.
    Oncogene 30:2986-2996.
  • Cawthorne C, Swindell R, Stratford IJ, Dive C, Welman A. 2007. Comparison of doxycycline delivery methods for Tet-inducible gene expression in a subcutaneous xenograft model.
    J Biomol Tech 18:120-123.
  • Martin-Fernandez C, Bales J, Hodgkinson C, Welman A, Welham MJ, Dive C, Morrow CJ. 2009. Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs.
    Mol Cancer Res 7:955-965.
  • Runck LA, Kramer M, Ciraolo G, Lewis AG, Guasch G. 2010. Identification of epithelial label-retaining cells at the transition between the anal canal and the rectum in mice.
    Cell Cycle 9:3039-3045.
  • Welman A, Cawthorne C, Ponce-Perez L, Barraclough J, Danson S, Murray S, Cummings J, Allen TD, Dive C. 2006. Increases in c-Src expression level and activity do not promote the growth of human colorectal carcinoma cells in vitro and in vivo.
    Neoplasia 8:905-916.
  • Reidy KJ, Villegas G, Teichman J, Veron D, Shen W, Jimenez J, Thomas D, Tufro A. 2009. Semaphorin3a regulates endothelial cell number and podocyte differentiation during glomerular development.
    Development 136:3979-3989.
  • Weng Y, Fang C, Turesky RJ, Behr M, Kaminsky LS, Ding X. 2007. Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.
    Cancer Res 67:7825-7832.
  • Daniel J, Coulter J, Woo JH, Wilsbach K, Gabrielson E. 2011. High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells.
    Proc Natl Acad Sci U S A 108:5384-5389.
  • Darrasse-Jeze G, Bergot AS, Durgeau A, Billiard F, Salomon BL, Cohen JL, Bellier B, Podsypanina K, Klatzmann D. 2009. Tumor emergence is sensed by self-specific CD44hi memory Tregs that create a dominant tolerogenic environment for tumors in mice.
    J Clin Invest 119:2648-2662.
  • Parsa S, Ramasamy SK, De Langhe S, Gupte VV, Haigh JJ, Medina D, Bellusci S. 2008. Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling.
    Dev Biol 317:121-131.
  • Podsypanina K, Politi K, Beverly LJ, Varmus HE. 2008. Oncogene cooperation in tumor maintenance and tumor recurrence in mouse mammary tumors induced by Myc and mutant Kras.
    Proc Natl Acad Sci U S A 105:5242-5247.
  • Ward AJ, Rimer M, Killian JM, Dowling JJ, Cooper TA. 2010. CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1.
    Hum Mol Genet 19:3614-3622.
  • Du YC, Klimstra DS, Varmus H. 2009. Activation of PyMT in beta cells induces irreversible hyperplasia, but oncogene-dependent acinar cell carcinomas when activated in pancreatic progenitors.
    PLoS One 4:e6932.
  • Borchers MT, Wesselkamper SC, Curull V, Ramirez-Sarmiento A, Sanchez-Font A, Garcia-Aymerich J, Coronell C, Lloreta J, Agusti AG, Gea J, Howington JA, Reed MF, Starnes SL, Harris NL, Vitucci M, Eppert BL, Motz GT, Fogel K, McGraw DW, Tichelaar JW, Orozco-Levi M. 2009. Sustained CTL activation by murine pulmonary epithelial cells promotes the development of COPD-like disease.
    J Clin Invest 119:636-649.
  • El-Hashash AH, Al Alam D, Turcatel G, Bellusci S, Warburton D. 2011. Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung.
    Dev Biol 350:112-126.
  • Le A, Zielinski R, He C, Crow MT, Biswal S, Tuder RM, Becker PM. 2009. Pulmonary epithelial neuropilin-1 deletion enhances development of cigarette smoke-induced emphysema.
    Am J Respir Crit Care Med 180:396-406.
  • Lian X, Qin Y, Hossain SA, Yang L, White A, Xu H, Shipley JM, Li T, Senior RM, Du H, Yan C. 2005. Overexpression of Stat3C in pulmonary epithelium protects against hyperoxic lung injury.
    J Immunol 174:7250-7256.
  • Manwani N, Gagnon S, Post M, Joza S, Muglia L, Cornejo S, Kaplan F, Sweezey NB. 2010. Reduced viability of mice with lung epithelial-specific knockout of glucocorticoid receptor.
    Am J Respir Cell Mol Biol 43:599-606.
  • Motz GT, Eppert BL, Wortham BW, Amos-Kroohs RM, Flury JL, Wesselkamper SC, Borchers MT. 2010. Chronic cigarette smoke exposure primes NK cell activation in a mouse model of chronic obstructive pulmonary disease.
    J Immunol 184:4460-4469.
  • Mucenski ML, Wert SE, Nation JM, Loudy DE, Huelsken J, Birchmeier W, Morrisey EE, Whitsett JA. 2003. beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis.
    J Biol Chem 278:40231-40238.
  • Perl AK, Riethmacher D, Whitsett JA. 2011. Conditional depletion of airway progenitor cells induces peribronchiolar fibrosis.
    Am J Respir Crit Care Med 183:511-521.
  • Politi K, Zakowski MF, Fan PD, Schonfeld EA, Pao W, Varmus HE. 2006. Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors.
    Genes Dev 20:1496-1510.
  • Premsrirut PK, Dow LE, Kim SY, Camiolo M, Malone CD, Miething C, Scuoppo C, Zuber J, Dickins RA, Kogan SC, Shroyer KR, Sordella R, Hannon GJ, Lowe SW. 2011. A rapid and scalable system for studying gene function in mice using conditional RNA interference. |
    Cell 145:145-158.
  • Regales L, Balak MN, Gong Y, Politi K, Sawai A, Le C, Koutcher JA, Solit DB, Rosen N, Zakowski MF, Pao W. 2007. Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors.
    PLoS One 2:e810.
  • Reynolds PR, Mucenski ML, Le Cras TD, Nichols WC, Whitsett JA. 2004. Midkine is regulated by hypoxia and causes pulmonary vascular remodeling.
    J Biol Chem 279:37124-37132.
  • Saini Y, Harkema JR, LaPres JJ. 2008. HIF1alpha is essential for normal intrauterine differentiation of alveolar epithelium and surfactant production in the newborn lung of mice.
    J Biol Chem 283:33650-33657.
  • Saini Y, Greenwood KK, Merrill C, Kim KY, Patial S, Parameswaran N, Harkema JR, LaPres JJ. 2010. Acute cobalt-induced lung injury and the role of hypoxia-inducible factor 1alpha in modulating inflammation.
    Toxicol Sci 116:673-681.
  • Saini Y, Kim KY, Lewandowski R, Bramble LA, Harkema JR, Lapres JJ. 2010. Role of hypoxia-inducible factor 1{alpha} in modulating cobalt-induced lung inflammation.
    Am J Physiol Lung Cell Mol Physiol 298:L139-147.
  • Sala FG, Del Moral PM, Tiozzo C, Alam DA, Warburton D, Grikscheit T, Veltmaat JM, Bellusci S. 2011. FGF10 controls the patterning of the tracheal cartilage rings via Shh.
    Development 138:273-282.
  • Tian Y, Zhou R, Rehg JE, Jackowski S. 2007. Role of phosphocholine cytidylyltransferase alpha in lung development.
    Mol Cell Biol 27:975-982.
  • Volckaert T, Dill E, Campbell A, Tiozzo C, Majka S, Bellusci S, De Langhe SP. 2011. Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.
    J Clin Invest 121:4409-4419.
  • Weng Y, Fang C, Turesky RJ, Behr M, Kaminsky LS, Ding X. 2007. Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.
    Cancer Res 67:7825-7832.
  • Wesselkamper SC, Eppert BL, Motz GT, Lau GW, Hassett DJ, Borchers MT. 2008. NKG2D is critical for NK cell activation in host defense against Pseudomonas aeruginosa respiratory infection.
    J Immunol 181:5481-5489.
  • Parsa S, Kuremoto K, Seidel K, Tabatabai R, Mackenzie B, Yamaza T, Akiyama K, Branch J, Koh CJ, Al Alam D, Klein OD, Bellusci S. 2010. Signaling by FGFR2b controls the regenerative capacity of adult mouse incisors.
    Development 137:3743-3752.
  • Diaz-Rodriguez E, Sotillo R, Schvartzman JM, Benezra R. 2008. Hec1 overexpression hyperactivates the mitotic checkpoint and induces tumor formation in vivo.
    Proc Natl Acad Sci U S A 105:16719-16724.
  • Sotillo R, Hernando E, Diaz-Rodriguez E, Teruya-Feldstein J, Cordon-Cardo C, Lowe SW, Benezra R. 2007. Mad2 overexpression promotes aneuploidy and tumorigenesis in mice.
    Cancer Cell 11:9-23.
  • Barraclough J, Hodgkinson C, Hogg A, Dive C, Welman A. 2007. Increases in c-Yes expression level and activity promote motility but not proliferation of human colorectal carcinoma cells.
    Neoplasia 9:745-754.
  • Bell EL, Emerling BM, Ricoult SJ, Guarente L. 2011. SirT3 suppresses hypoxia inducible factor 1alpha and tumor growth by inhibiting mitochondrial ROS production.
    Oncogene 30:2986-2996.
  • Cawthorne C, Swindell R, Stratford IJ, Dive C, Welman A. 2007. Comparison of doxycycline delivery methods for Tet-inducible gene expression in a subcutaneous xenograft model.
    J Biomol Tech 18:120-123.
  • Daniel J, Coulter J, Woo JH, Wilsbach K, Gabrielson E. 2011. High levels of the Mps1 checkpoint protein are protective of aneuploidy in breast cancer cells.
    Proc Natl Acad Sci U S A 108:5384-5389.
  • Martin-Fernandez C, Bales J, Hodgkinson C, Welman A, Welham MJ, Dive C, Morrow CJ. 2009. Blocking phosphoinositide 3-kinase activity in colorectal cancer cells reduces proliferation but does not increase apoptosis alone or in combination with cytotoxic drugs.
    Mol Cancer Res 7:955-965.
  • Parsa S, Ramasamy SK, De Langhe S, Gupte VV, Haigh JJ, Medina D, Bellusci S. 2008. Terminal end bud maintenance in mammary gland is dependent upon FGFR2b signaling.
    Dev Biol 317:121-131.
  • Welman A, Cawthorne C, Ponce-Perez L, Barraclough J, Danson S, Murray S, Cummings J, Allen TD, Dive C. 2006. Increases in c-Src expression level and activity do not promote the growth of human colorectal carcinoma cells in vitro and in vivo.
    Neoplasia 8:905-916.

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