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Pharmacokinetics

Understanding the pharmacokinetics of your drug is critical to its development, and generating early reliable pharmacokinetic data can significantly impact the outcomes of your research & development project.  At Envigo, we strive to help you quickly make the most out of your drug metabolism and pharmacokinetic data.  As your drug development ally, we secure the potential for your product by defining product clearance and prediction to human, helping you choose the most appropriate toxicology species, enhancing your understanding of the link between exposure and safety, and characterizing the correlation between pharmacokinetics and pharmacodynamics (PK/PD).  Our team of  pharmacokinetic study directors is committed to providing you with unmatched customer service, including a single point of control who works closely with you from study initiation to data generation.

Our  PK study types

  • Rapid screening PK
  • Bioavailability and Bioequivalence
  • Toxicokinetics
  • Blood-brain barrier transfer
  • Absorption studies
  • Tissue distribution
  • PK/PD
  • Formulation comparison
  • Food effect
  • Non-compartmental and compartmental pharmacokinetics
     

Our PK services

  • Dedicated or rental non-rodent (dog, primate and minipig) colonies
  • Surgical models
  • Multiple routes for test item administration
  • Cassette dosing
  • Microsampling
  • Tissue, CSF and urine sampling
  • Integrated bioanalytical support
  • Automated data transfer
  • Template reports (standard or bespoke)
  • Flexible scheduling
  • Rapid turnaround times

Avista and Envigo press release

The future of inhaled medications and inhalation technology

[Webinar] De-risking drug development: in vitro strategies that add value to your molecule