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Biotransformation

Envigo has a dedicated group specializing in biotransformation studies, which is underpinned by broad experience and a comprehensive knowledge in chromatographic analysis and mammalian biotransformation pathways; this includes scientists whose primary specialism is in the structural elucidation of unknowns using mass spectrometry.
Equipment available:

  • Radiochromatography with flow-through or stop-flow detection
  • Off-line fraction collection into wellplates and detection using TopCount
  • Thermo Q-Exactive Focus with ThermoScientific Ultimate 3000
  • AB Sciex QTrap 4000 with Agilent 1200

Our scientists have extensive experience in the analysis and characterization of small and large molecules and their metabolites from radiolabelled and non-radiolabelled studies, mostly unsupported by availability of corresponding reference compounds.

Avista and Envigo press release

The future of inhaled medications and inhalation technology

[Webinar] De-risking drug development: in vitro strategies that add value to your molecule